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LYST
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18043242 |
CHS1/LYST protein is involved in either vesicle fusion or fission. CHS1/LYST affects hematologic, immunologic and neurologic processes. Review. |
| 15896657 |
two newly described nonsense mutations are expected to give rise to a severe phenotype and the patient had absolutely no cytotoxicity by natural killer cells or cytotoxic lymphocytes |
| 11857544 |
Childhood, adolescent, and adult forms of Chediak-Higashi syndrome correlate with different genotypes. |
| 12753649 |
results suggest that the Beige protein interacts with at least two different partners and that the Beige protein affects cellular events, such as nuclear PtdIns(4,5)P2 localization, in addition to lysosome size |
| 11984006 |
The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins. |
Recent Publications on LYST: |  |
HIV-1 Nef promotes endocytosis of cell surface MHC class II molecules via a constitutive pathway.
HIV-1 Nef has been reported to disrupt MHC class II (MHCII)-mediated Ag... | 10th September, 2009
| National Institute of Immunology, New Delhi, India.
| J Immunol. 2009 Aug 15;183(4):2415-24. Epub 2009 Jul 20.
DOI Direct Link |
Spinal cord mRNA profile in patients with ALS: comparison with transgenic mice expressing the human SOD-1 mutant.
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative... | 1st September, 2009
| Felsenstein Medical Research Center, Department of Neurology, Rabin
| J Mol Neurosci. 2009 Jun;38(2):85-93. Epub 2008 Jul 24.
DOI Direct Link |
A concanavalin A-like lectin domain in the CHS1/LYST protein, shared by members of the BEACH family.
CHS1/LYST, the causative protein of the Chediak-Higashi syndrome (CHS),... | 19th June, 2009
| INSERM, U768, Paris, F-75015, France.
| Bioinformatics. 2009 May 15;25(10):1219-22. Epub 2009 Mar 16.
DOI Direct Link |
Lyst mutation in mice recapitulates iris defects of human exfoliation syndrome.
PURPOSE: Human eyes with exfoliation syndrome (XFS) exhibit a distinctive... | 24th March, 2009
| Department of Molecular Physiology, University of Iowa, Iowa City, Iowa
| Invest Ophthalmol Vis Sci. 2009 Mar;50(3):1205-14. Epub 2008 Nov 21.
DOI Direct Link |
Prolonged survival of microencapsulated neonatal porcine islet xenografts in immune-competent mice without antirejection therapy.
Several studies have demonstrated that in vitro culture of islets... | 24th February, 2009
| Surgical-Medical Research Institute, Department of Surgery, University of
| Cell Transplant. 2008;17(10-11):1243-56.
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