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GABARAPL2

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Symbol:	GABARAPL2
Name(s):	GABA(A) receptor-associated protein-like 2
Type:	protein-coding
Organism:	Homo sapiens
Synonyms:	ATG8, GATE-16, GATE16, GEF-2, GEF2
Links:	Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications
Publication Link	Summary of findings
16303767	Phosphatidylserine and phosphatidylethanolamine are targets of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16

Interacting gene products
Interaction Type	Gene 1	Gene 2	Interaction description	Complex	Publication Link
HPRD	N ethylmaleimide sensitive factor	GABA(A) receptor-associated protein-like 2	-	-	Pubmed
HPRD	Unc 51 like kinase 1	GABA(A) receptor-associated protein-like 2	-	-	Pubmed
HPRD	unc-51-like kinase 1	Ganglioside expression factor 2	-	-	Pubmed
HPRD	28 kDa cis-Golgi SNARE p28	GABA(A) receptor-associated protein-like 2	-	-	Pubmed
HPRD	APG7 autophagy 7 like	GABA(A) receptor-associated protein-like 2	-	-	Pubmed
HPRD	APG7 autophagy 7-like	Ganglioside expression factor 2	-	-	Pubmed

Recent Publications on GABARAPL2:
Structure and potential function of gamma-aminobutyrate type A receptor-associated protein. The gamma-aminobutyrate type A receptor-associated protein (GABARAP) is a...	16th September, 2009	Institut fur Strukturbiologie und Biophysik (ISB-3), Forschungszentrum	FEBS J. 2009 Sep;276(18):4989-5005. Epub 2009 Aug 6. DOI Direct Link
A novel role for MAP1 LC3 in nonautophagic cytoplasmic vacuolation death of cancer cells. Thiol reactive cyclopentenone prostaglandin,...	18th August, 2009	Department of Pathology, University of Texas Health Science Center at San	Oncogene. 2009 Jul 16;28(28):2556-68. Epub 2009 May 18. DOI Direct Link
Contribution of energy restriction and macronutrient composition to changes in adipose tissue gene expression during dietary weight-loss programs in obese women. CONTEXT: Hypoenergetic diets are used to reduce body fat mass and...	1st January, 2009	Laboratoire de Recherches sur les Obesites, Institut National de la Sante	J Clin Endocrinol Metab. 2008 Nov;93(11):4315-22. Epub 2008 Sep 9. DOI Direct Link
Autophagy-independent incorporation of GFP-LC3 into protein aggregates is dependent on its interaction with p62/SQSTM1. LC3 is a widely used marker of autophagosomes in mammalian cells. However,...	1st January, 2009	Department of Biological Chemistry, The Weizmann Institute of Science,	Autophagy. 2008 Nov 16;4(8):1054-6. Epub 2008 Nov 20.
Evolution and expression of gamma-aminobutyric acid type A receptor-associated protein from the amphioxus Branchiostoma belcheri. The cDNA encoding a gamma-aminobutyric acid type A (GABA(A))...	13th September, 2008	Department of Marine Biology, Ocean University of China, Qingdao, People's	DNA Seq. 2008 Jun;19(3):319-25. DOI Direct Link
→View more research publications.

Patents:
US Patent No.	Title
7611839	Methods for diagnosing RCC and other solid tumors
7598080	Diagnostic assay for source of inflammation
7547687	Therapeutic treatment methods
7482334	Therapeutic treatment methods
7465542	Methods and compositions for determining risk of treatment toxicity
→View more patents.

GABARAPL2 results (if any) from reagent suppliers

Autophagy GABARAPL2 (GATE16) Antibody (F77) Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with Autophagy GABARAPL2* (GATE16) antibody (F77), ... http://www.abgent.com/products/catalog_no/AP1822c...
GABARAPL2 antibodies: Signal Transduction > Protein Trafficking ... GABARAPL2 antibodies. ... GABARAPL2 antibody. IHC-P, WB, IHC-Fr. Sheep polyclonal ... GABARAPL2 antibody. WB, ELISA, IHC-Fr. Rabbit polyclonal ... http://www.abcam.com/index.html?t=99499&pt=1&c=2249&ei=&mu=r...
Product Line - Autophagy Antibody AP1821a, GABARAP Antibody (N-term), WB, IHC, IF, E, H. AP1822c, GABARAPL2 ( GATE16) Antibody (F77), IHC, E, H. AP2161a, HGS Antibody (N-term), WB, IHC, E, H ... http://www.abgent.com/products/category/autophagy...
ATG4B antibody, ATG4B (ATG4 autophagy related 4 homolog B (S ... Function: Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of ... http://www.genwaybio.com/product_info.php?products_id=44646...
Anti-ATG7 Polyclonal Antibody Forms intermediate conjugates with GABARAPL1 (GABARAPL2, GABARAP or MAP1ALC3). Formation of the final GABARAPL1-PE conjugate is essential for autophagy. ... http://www.bioreagents.com/products/productDetails/productDe...
Abgent Antibodies and Peptides AP1825c, DRAM (C-term), IHC, H. AP1825b, DRAM (C-term)-2, IHC, WB, H. AP1821a, GABARAP (N-term), IHC, WB, H. AP1822c, GABARAPL2 (GATE16) (F77), IHC, H ... http://www.abgent.com/docs/kits_autophagy...
GABARAP-2 siRNA (m) sc-41959 Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Gabarapl2, 93739, 8 E1, P60521 ... http://www.scbt.com/datasheet-41959-gabarap-2-sirna-m.html...

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