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CHRNA7


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Symbol:CHRNA7
Name(s):cholinergic receptor, nicotinic, alpha 7
Type:protein-coding
Organism:Homo sapiens
Synonyms:NACHRA7
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18073210 M1 muscarinic and alpha7 nicotinic receptors have roles in inhibition of pemphigus acantholysis
18198266 Observational study of gene-disease association. (HuGE Navigator)
11150893 Observational study of gene-disease association. (HuGE Navigator)
11455129 Observational study of gene-disease association. (HuGE Navigator)
11532536 Observational study of gene-disease association. (HuGE Navigator)
11803513 Observational study of gene-disease association. (HuGE Navigator)
12214130 Observational study of gene-disease association. (HuGE Navigator)
12470124 Observational study of gene-disease association. (HuGE Navigator)
14569275 Observational study of gene-disease association. (HuGE Navigator)
14582144 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDAdenylate cyclase 6cholinergic receptor, nicotinic, alpha 7 precursor--Pubmed
HPRDadenylate cyclase 6 isoform aCholinergic receptor neuronal nicotinic alpha polypeptide 7--Pubmed
HPRDcholinergic receptor, nicotinic, alpha 7 precursorPhosphatidylinositol 3 kinase regulatory subunit, alpha--Pubmed

Recent Publications on CHRNA7:

Pubmed Logo
Genome-Wide Scan of Copy Number Variation in Late-Onset Alzheimer's Disease.
Alzheimer's disease is a complex and progressive neurodegenerative disease...
15th September, 2009
Institute for Genome Sciences & Policy, Center for Human Genome Variation, J Alzheimers Dis. 2009 Sep 11.
DOI Direct Link
Differential Regulation of alpha7 Nicotinic Receptor Gene (CHRNA7) Expression in Schizophrenic Smokers.
The alpha7 neuronal nicotinic receptor gene (CHRNA7) has been implicated...
15th August, 2009
Cenomed BioSciences, Irvine, CA, USA. J Mol Neurosci. 2009 Aug 13.
DOI Direct Link
Examination of the nicotine dependence (NICSNP) consortium findings in the Iowa adoption studies population.
INTRODUCTION: Nicotine dependence results from a complex interplay of...
6th August, 2009
Department of Psychiatry and Neuroscience and Genetics Programs, Nicotine Tob Res. 2009 Mar;11(3):286-92. Epub 2009 Mar 23.
DOI Direct Link
A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.
Multiple genetic linkage studies support the hypothesis that the 15q13-14...
28th July, 2009
Department of Psychiatry, University of Colorado at Denver, Denver, CO Brain Res. 2009 Sep 29;1291:1-11. Epub 2009 Jul 23.
DOI Direct Link
The copy number variant involving part of the alpha7 nicotinic receptor gene contains a polymorphic inversion.
The alpha7 nicotinic acetylcholine receptor gene (CHRNA7) is located at...
25th July, 2009
Department of Psychological Medicine, Division of Psychological Medicine, Eur J Hum Genet. 2008 Nov;16(11):1364-71. Epub 2008 Jun 11.
DOI Direct Link

View more research publications.

BioNews Results for CHRNA7

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BioPortfolio Logo
Genes Play A Role In Learning And Behavior Abnormalities
MedIndia:  Nov 11 2009 12:32PM Matching: chrna7
Erratum to: Differential Regulation of alpha7 Nicotinic Receptor Gene (CHRNA7) Expression in Schizophrenic Smo
Bioscience Technology Online:  Nov 11 2009 11:13AM Matching: chrna7
Gene linked to abnormalities in learning, behaviour identified
Topnews.in:  Nov 9 2009 1:43PM Matching: chrna7
Developmental Delay May Stem from Nicotinic Receptor Deletion
Genetic Engineering News:  Nov 9 2009 10:10PM Matching: chrna7
Medical News: Nicotinic Receptor Deletion Could Result In Developmental Delay
BioFind:  Nov 9 2009 1:50PM Matching: chrna7
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Neural Inhibition as a Mechanism of Nicotine Dependence Among Persons With Schizophrenia

Patents:

Patents logo
US Patent No.Title
7598052 Expression profile of thyroid cancer
6760715 Enhancing biological knowledge discovery using multiples support vector machines
6727063 Single nucleotide polymorphisms in genes
6714925 System for identifying patterns in biological data using a distributed network
6673908 Tumor necrosis factor receptor 2

View more patents.

CHRNA7 results (if any) from reagent suppliers

Google CSE Logo
Antibodies to Nicotinic Acetylcholine Receptors
CHRNA7(1139) rat ... Chrna7(25302), human (denatured), rat (denatured), chicken ... rat ... Chrna7(25302), chicken, rat, human, IHC (p), WB, pricing ...
https://www.sigmaaldrich.com/etc/controller/controller-page....

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AChRα7 (C-20) Antibody sc-1447
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, CHRNA7, 1139, 15q13.3, NM_000746 ...
http://www.scbt.com/datasheet-1447-achralpha7-c-20-antibody....

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M220 Monoclonal Anti-Nicotinic Acetylcholine Receptor (α7 Subunit ...
isotype, IgG1. Gene Information, human ... CHRNA7(1139). rat ... Chrna7(25302). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=M220...

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Nicotinic Acetylcholine Receptor alpha 7 antibody (ab10096) | Abcam
ab10096 at 1/1000 dilution staining approximately 56kDa band of mouse CHRNA7 in mouse muscle lysate by Western blot (ECL). Product image ...
http://www.abcam.com/nicotinic-acetylcholine-receptor-alpha-...

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AChRα (G10) Antibody sc-32252
Mouse, Chrna7, 11441, 7 C, P49582, N/A. Mouse, Chrna3, 110834, 9 B, Q8R4G9, N/A. Mouse, Chrna5, 110835, 9 B, Q2MKA5, N/A. Mouse, Chrna2, 110902, 14 D1 ...
http://www.scbt.com/datasheet-32252-achralpha-g10-antibody.h...

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Search Results
Stock# - 003232 Strain name - B6.129S7-Chrna7/J JAX® Mice Database Site Section: JAX® Mice and services · jaxmice.jax.org/strain/003232.html - 54Kb ...
http://www.jax.org/search/Main.jsp?sg=4&qt=sperm&page=6...

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