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CISH


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Symbol:CISH
Name(s):cytokine inducible SH2-containing protein
Type:protein-coding
Organism:Homo sapiens
Synonyms:CIS, CIS-1, G18, SOCS
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17666591 analysis of STAT5, CIS, and SOCS2 interactions with the growth hormone receptor
14630083 Up-regulation of cytokine inducible SH2-containing protein is associated with adult T-cell leukemia
16684815 CIS (cytokine-inducible SH2 protein)is binding with the conserved Y985 and Y1077 motifs in the cytosolic domain of the leptin receptor.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCytokine inducible SH2 containing proteinerythropoietin receptor precursor--Pubmed
HPRDCytokine inducible SH2 containing proteinerythropoietin receptor precursor--Pubmed
HPRDCytokine inducible SH2 containing proteininterleukin 2 receptor beta precursor--Pubmed
HPRDCytokine inducible SH2 containing proteininterleukin 3 receptor, alpha precursor--Pubmed
HPRDCytokine inducible SH2 containing proteinmitogen-activated protein kinase kinase 1 interacting protein 1--Pubmed

Recent Publications on CISH:

Pubmed Logo
[Proteomic expression analysis of human colorectal cancer: of soluble overexpressed proteins]
Colon cancer is one of the leading causes of cancer deaths in developed...
8th October, 2009
Mol Biol (Mosk). 2009 Jul-Aug;43(4):610-5.
HER2/neu (c-erbB-2) gene amplification and protein expression are rare in uterine cervical neoplasia: a tissue microarray study of 814 archival specimens.
Published studies have reported widely variable incidence of HER2/neu...
7th October, 2009
Institute of Pathology, Aarhus University Hospital, Norrebrogade 44, APMIS. 2009 Oct;117(10):737-45.
DOI Direct Link
[Comparison of clinicopathologic characteristics and prognosis of triple-negative with Her-2-overexpressing breast cancer]
OBJECTIVE: The aim of this study is to compare the clinicopathologic...
6th October, 2009
Department of Oncology, Changhai Hospital, the Second Military Medical Zhonghua Zhong Liu Za Zhi. 2009 May;31(5):346-50.
Chromogenic in situ hybridization analysis of EGFR gene copies in colon adenocarcinoma based on intra-operative imprints and tissue microarrays.
BACKGROUND: Although Epidermal Growth Factor Receptor (EGFR) over...
2nd October, 2009
Medical School, University of Athens;Dept of Pathology, 417 VA Hospital J Gastrointestin Liver Dis. 2009 Sep;18(3):293-8.
Emerging technologies for assessing HER2 amplification.
Patients with human epidermal growth factor receptor-2 (HER2)+ breast...
2nd October, 2009
Department de Pathologie, Centre Jean Perrin, 63011 Clermont-Ferrand Am J Clin Pathol. 2009 Oct;132(4):539-48.
DOI Direct Link

View more research publications.

Press Releases on CISH:

BioPortfolio Logo
Monogram Announces 2008 Third Quarter Financial Results 27th October, 2008 Monogram Biosciences, Inc.

SOUTH SAN FRANCISCO, Calif., Oct. 27 /PRNewswire-FirstCall/ -- Monogram Biosciences, Inc. (Nasdaq: MGRM) today reported financial results for the quarter ended September 30, 2008.

Monogram Announces 2008 Second Quarter Financial Results 29th July, 2008 Monogram Biosciences, Inc.

SOUTH SAN FRANCISCO, Calif., July 29 /PRNewswire-FirstCall/ -- Monogram Biosciences, Inc. (Nasdaq: MGRM) today reported financial results for the quarter ended June 30, 2008.

The

Monogram Announces Commercial Availability of the HERmark(TM) Breast Cancer Assay 8th July, 2008 Monogram Biosciences, Inc.

SOUTH SAN FRANCISCO, Calif., July 8 /PRNewswire-FirstCall/ -- Monogram Biosciences, Inc. (Nasdaq: MGRM) today announced that, effective July 15, the HERmark(TM) Breast Cancer Assay will be

Clinical Trials:

Clinical Trials Logo
Panitumumab and Irinotecan as Third-Line Therapy in Treating Patients With Metastatic Colorectal Cancer

Patents:

Patents logo
US Patent No.Title
7602954 Method for quantitative video-microscopy and associated system and computer software program product
6706867 DNA array sequence selection
6942970 Identifying subjects suitable for topoisomerase II inhibitor treatment
6979724 Calcium channel proteins
7133547 Method for quantitative video-microscopy and associated system and computer software program product

View more patents.

CISH results (if any) from reagent suppliers

Google CSE Logo
CISH Technology Overview
CISH, or chromogenic in situ hybridization, is a process in which a labeled complementary DNA or RNA strand is used to localize a specific DNA or RNA ...
http://www.invitrogen.com/site/us/en/home/Products-and-Servi...

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Biocare Medical - SPOT-Light® HER2 CISH Kit
The SPOT-Light® HER2 CISH Kit is FDA approved as an alternative for IHC or FISH methods. ... Click Here to find more about the FDA approved HER2 CISH Kit ...
http://www.biocare.net/her2cish.html...

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CISH - Chromogenic In Situ Hybridization
Chromogenic In Situ Hybridization (CISH) allows detection of gene amplification, chromosome translocations and chromosome number using conventional ...
http://www.histo-line.it/eng/contents/cish.wbl...

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CISH antibodies: Chromatin and Nuclear Signaling > Transcription ...
CISH antibodies. ... Image Abreview Publication. ab5923 · CISH antibody. IP, WB, ELISA. Images. Rabbit polyclonal. Reacts with: Ms. Predicted: Hu, Rat ...
http://www.abcam.com/index.html?t=86832&pt=1&c=3424&ei=&mu=r...

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CISH_HER2_BrstCA 110600.062205art
Chromogenic in situ hybridization (CISH): A practical method ... In order to accurately identify HER-2 status, we have developed CISH which uses HER-2 DNA
...
http://www.invitrogen.com/etc/medialib/en/filelibrary/pdf.Pa...

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Antibodies, Immunohistochemistry, Laboratory Equipment ...
NEW predilutes formulated for VP Echelon · > SPOT-Light® HER2 CISH Kit · Home | Biocare | Products | News | Events | Order | Support | Contact Us ...
http://www.biocare.net/...

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HER2 STATUS ASSESSMENT BY CHROMOGENIC IN-SITU HYBRIDISATION (CISH ...
cell by CISH were classified as HER2 positive. Patients with .... in-situ hybridisation (CISH) with FISH and IHC for assessment of HER2 ...
http://www.invitrogen.com/etc/medialib/en/filelibrary/clinic...

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