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ANTXR2


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Gene DB Home
Symbol:ANTXR2
Name(s):anthrax toxin receptor 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:CMG-2, CMG2, FLJ31074, ISH, JHF, MGC111533, MGC45856
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15079089 structures provide a template to begin probing the high-affinity capillary morphogenesis protein 2-protective antigen interaction and may facilitate understanding of toxin assembly/internalization
16401723 Data show that cells expressing palmitoylation-defective mutant receptors are less sensitive to anthrax toxin due to a lower number of surface receptors as well as premature internalization of protective antigen without a requirement for heptamerization.
12973667 identification and characterization of juvenile hyaline fibromatosis and infantile systemic hyalinosis disease-causing mutations in the capillary morphogenesis factor-2 gene
16473908 Molecular dynamics simulations explain the great strength that the protective antigen-capillary morphogenesis gene 2 complex achieves through extraordinary coordination of a divalent cation.
14508707 identification of 15 different mutations in the gene encoding capillary morphogenesis protein 2 in 17 families with juvenile hyaline fibromatosis or infantile systemic hyalinosis
15243628 crystal structure of the complex with anthrax toxin

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDalpha 3 type IV collagen isoform 1, precursoranthrax toxin receptor 2--Pubmed
HPRDalpha 4 type IV collagen precursoranthrax toxin receptor 2--Pubmed
HPRDalpha 4 type IV collagen precursoranthrax toxin receptor 2--Pubmed

ANTXR2 results (if any) from reagent suppliers

Google CSE Logo
ANTXR2 antibodies: Neuroscience > Cell Adhesion Proteins ...
ANTXR2 antibodies. ... ANTXR2 antibodies. Code. Name. Applications (see key) & Reactivity (see key). Image Abreview Publication. ab70499 · ANTXR2 antibody ...
http://www.abcam.com/index.html?t=268098&pt=1&c=412&ei=&mu=r...

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ORDERING INFORMATION
receptor 2 (ANTXR2) is a type I membrane protein with a von Willebrand factor A/ integrin-like inserted domain in its extracellular region. CMG-2 binds ...
http://www.rndsystems.com/pdf/AF3636.pdf...

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All ECM Proteins | Abcam
ANTXR2 antibody. WB. Images. Mouse polyclonal. Reacts with: RecFrag. Predicted: Hu. ab49700 · Arachis hypogaea Lectin antibody. DID. Rabbit polyclonal ...
http://www.abcam.com/index.html?c=756...

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ATR2/CMG2 siRNA (m) sc-60232
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Antxr2, 71914, 5 E3, Q6DFX2 ...
http://www.scbt.com/datasheet-60232-atr2-cmg2-sirna-m.html...

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All Cell Adhesion Proteins | Abcam
ANTXR2 antibody. WB. Images. Mouse polyclonal. Reacts with: RecFrag. Predicted: Hu. ab82769 · ASTN2 antibody. WB, ELISA. Images. Rabbit polyclonal ...
http://www.abcam.com/index.html?c=349...

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ATR2/CMG2 siRNA (h) sc-60231
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ANTXR2, 118429, 4q21.21, NM_058172 ...
http://www.scbt.com/datasheet-60231-atr2-cmg2-sirna-h.html...

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March 07 NPR_031307_No Prices.indd
CMG-2/ANTXR2. Human. NS0. 2940-CM-050. 50 µg. Cyclophilin A .... ANTXR2. Mouse. Goat IgG. AF3636. 100 µg. Coagulation Factor VII ...
http://www.rndsystems.com/DAM_public/5886.pdf...

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