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HIST4H4


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Symbol:HIST4H4
Name(s):histone cluster 4, H4
Type:protein-coding
Organism:Homo sapiens
Synonyms:H4/p, MGC24116
Links: Pubmed, Entrez Gene, GeneCards, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17848202 Brd2 bromodomain 2 is monomeric in solution and dynamically interacts with H4-AcK12; additional secondary elements in the long ZA loop may be a common characteristic of BET bromodomains.
17548343 H4 tail and its acetylation have novel roles in mediating recruitment of multiple regulatory factors that can change chromatin states for transcription regulation
16782888 BTG2 contributes to retinoic acid activity by favoring differentiation through a gene-specific modification of histone H4 arginine methylation and acetylation levels.
16531610 Apoptosis is associated with global DNA hypomethylation and histone deacetylation events in leukemia cells.
15095300 overexpression of MTA1 protein and acetylation level of histone H4 protein are closely related
12385581 low levels of histone acetylation is associated with the development and progression of gastric carcinomas, possibly through alteration of gene expression
17522015 Relationship between histone H4 modification, epigenetic regulation of BDNF gene expression, and long-term memory for extinction of conditioned fear.
15345777 peptidylarginine deiminase 4 regulates histone Arg methylation by converting methyl-Arg to citrulline and releasing methylamine; data suggest that PAD4 mediates gene expression by regulating Arg methylation and citrullination in histones
16177192 lack of biotinylation of K12 in histone H4 is an early signaling event in response to double-strand breaks
16322686 The decrease in trimethylation of lysine 20 of histone H4 in breast cancer cells was accompanied by diminished expression of Suv4-20h2 histone methyltransferase.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDHomo sapiens chromosome 4histone cluster 4, H4HIST4H4 (Histone 4) interacts with the ALB gene (albumin).-Pubmed
BINDHuman p21 gene, partial promoter sequence.histone cluster 4, H4HIST4H4 (H4) interacts with the p21 promoter.-Pubmed
BINDHuman p21 gene, partial promoter sequence.histone cluster 4, H4HIST4H4 (H4) interacts with the CDKN1A promoter.-Pubmed
BINDHomo sapiens chromosome 6histone cluster 4, H4HIST4H4 (histone H4) interacts with the CNR1 promoter.-Pubmed
HPRDgrowth arrest and DNA-damage-inducible, alphahistone cluster 4, H4--Pubmed
BINDE1A binding protein p300histone cluster 4, H4EP300 (p300) interacts with HIST4H4 (histone 4)-Pubmed
BINDHomo sapiens interferon-inducible peptide precursor gene, complete cds, alternatively spliced.histone cluster 4, H4H4 interacts with p-G1P3.-Pubmed
BINDHomo sapiens glutathione S-transferase pi gene, complete cds.histone cluster 4, H4HIST4H4 (H4) interacts with the GSTP1 promoter.-Pubmed
BIND-histone cluster 4, H4Mdm2 interacts with H4.-Pubmed
BINDHomo sapiens DNA for O6-methylguanine-DNA-methyltransferase promoterhistone cluster 4, H4HIST4H4 (H4) interacts with the MGMT promoter.-Pubmed

Recent Publications on HIST4H4:

Pubmed Logo
A novel replication-independent histone H2a gene in mouse.
BACKGROUND: An uncharacterized histone H2a-coding transcript (E130307C13)...
25th May, 2006
Laboratory for Genome Exploration Research Group, RIKEN Genomic Sciences BMC Genet. 2005 Feb 19;6(1):10.
DOI Direct Link

HIST4H4 results (if any) from reagent suppliers

Google CSE Logo
Histone H4 Antibody AbVantage Pack
Affinity Purified. Anti-H4 Antibody, Anti-Histone H4 Antibody, Anti-H4/p. Antibody, Anti-Hist4H4 Antibody. Produced in Rabbit. Catalog No. A300-646A ...
http://www.natutec.de/pdf_bethyl/A310-189A.pdf...

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H9164 Anti acetyl Histone H4 Ac Lys16 antibody produced in rabbit ...
concentration. ~1.5 mg/mL. application(s). immunoblotting: 1-2 μg/mL using HL60 cell lysates. Gene Information. human ... HIST4H4(121504). shipped in ...
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...

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Histone H4 IHC Antibody
Anti-H4 IHC Antibody, Anti-Histone H4 IHC Antibody, Anti-H4/p IHC Antibody, Anti -Hist4H4 IHC Antibod. Histone H4 IHC Antibody. Produced in Rabbit ...
http://www.natutec.de/pdf_bethyl/IHC-00098.pdf...

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NM_175054 histone 4; H4 MISSION® shRNA Bacterial Glycerol Stock
RefSeq. NM_175054. Gene Description. histone 4; H4. Organism. Human. Gene ID. 121504. Symbol. HIST4H4. Taxon ID. 9606. MISSION™ TRC shRNA Target Set ...
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...

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Chromosome 6 - Santa Cruz Biotechnology, Inc.
GC-C · sc-45493, MR. Hist4h4 · 320332, 6 G1, NM_175652 · P62806 · Histone H4 · sc-35566, TR. H2afj · 232440, 6 G1, NM_177688 · NP_808356 ...
http://www.scbt.com/chromosome.php?number=6&page=27&species=...

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Hist1h4j histone cluster 1, H4j
HIST4H4(Human); Hist1h4k(Mouse). Function(s). DNA binding. Replaces Gene ID(s). 260424. Available Product(s). siRNA, shRNA. Useful External Links ...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...

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