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NOXO1
| Symbol: | NOXO1 | | Name(s): | NADPH oxidase organizer 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | MGC20258, P41NOX, P41NOXA, P41NOXB, P41NOXC, SH3PXD5, SNX28 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 15949904 |
Data suggest different tissue localizations and functions for NOXO1beta and NOXO1gamma in regulating Nox family members. |
| 16911517 |
This study shows the expression of alternatively spliced transcripts of the NOXO1 gene and the roles of the protein products in the activation of Nox oxidases. |
| 17126813 |
These findings suggest that Nox activation involves a conformational change leading to disruption of the bis-SH3-PRR interaction in Noxo1. |
| 14617635 |
NOXO1 and NOXA1 activate Nox1 without the need for agonist activation, and this is mediated in part by binding of the NOXO1 PX domain to membrane lipids. |
| 15181005 |
NOXO1, p47phox, and p67phox regulate Nox3 |
| 16329988 |
These results suggest that the formation of the complex consisting of Nox1, betaPix, and NoxO1 is likely to be a critical step in EGF-induced ROS generation. |
| 12716910 |
A novel human homolog to p47-phox. |
Recent Publications on NOXO1: |  |
Tumor necrosis factor alpha activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells.
NADPH oxidase 1 (Nox1) is a multicomponent enzyme consisting of p22(phox),... | 22nd October, 2008
| Department of Stress Science, Institute of Health Biosciences, University
| Free Radic Biol Med. 2008 Sep 23.
DOI Direct Link |
Activation of NADPH oxidase 1 in tumour colon epithelial cells.
In the plasma membrane fraction from Caco-2 human colon carcinoma cells,... | 7th October, 2008
| Department of Biochemistry, Aichi Medical University, School of Medicine,
| Biochem J. 2008 Oct 1;415(1):57-65.
DOI Direct Link |
Essential role of NOXA1 in generation of reactive oxygen species induced by oxidized low-density lipoprotein in human vascular endothelial cells.
Oxidative stress induced by superoxide plays an important role in... | 7th August, 2008
| Division of Cardiovascular and Respiratory Medicine, Department of
| Endothelium. 2008 May-Jun;15(3):137-41.
DOI Direct Link |
Mechanism of angiotensin II-induced superoxide production in cells reconstituted with angiotensin type 1 receptor and the components of NADPH oxidase.
The mechanism of angiotensin II (Ang II)-induced superoxide production was... | 18th June, 2008
| Division of Life and Pharmaceutical Sciences, Ewha Womans University, 11-1
| J Biol Chem. 2008 Jan 4;283(1):255-67. Epub 2007 Nov 2.
DOI Direct Link |
IL-8 production and AP-1 transactivation induced by UVA in human keratinocytes: roles of D-alpha-tocopherol.
Identification of individual response-signal pathway induced by... | 6th June, 2008
| Medicine Clinic III, Campus Benjamin Franklin, Charite-Universitatsmedizin
| Mol Immunol. 2008 Apr;45(8):2288-96. Epub 2008 Feb 21.
DOI Direct Link |
→View more research publications. |
NOXO1 results (if any) from reagent suppliers | 
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NOXO1 Antibody / NOXO1 Antibodies
NOXO1 Antibody / NOXO1 Antibodies. ... NOXO1 specific siRNA and shRNA gene silencers are also available. These include: NOXO1 siRNA (h): sc-75949, ...
http://www.scbt.com/table-noxo1.html...
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NOXO1 antibody (ab34761) datasheet | Abcam
Rabbit polyclonal to NOXO1. NOXO1 (Nox organizing protein 1) and NOXA1 (Nox Activating protein 1) are homologs of p47phox and p67phox. p47phox functions in
...
http://www.abcam.com/index.html?datasheet=34761...
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NOXO1 siRNA (h) sc-75949
Click here for details. contact Technical Service for availability of control antibody; RT-PCR Primer also available: NOXO1 (h)-PR: sc-75949-PR, 20 µl ...
http://www.scbt.com/datasheet-75949-noxo1-sirna-h.html...
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NOX1 antibody (ab55831) datasheet | Abcam
It requires interaction with NOXO1 and NOXA1 for superoxide generation. Alternative names for NOX1 antibody (ab55831). Database links ...
http://www.abcam.com/index.html?datasheet=55831...
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24347 Lot A
NOXO1. Rb. 600-401-899. IHC, WB, IP, E 100μg. p27. Rb. 100-401-172. WB, IP, E. 100μl. Product. Host Part Number. Applications Size ...
http://www.rockland-inc.com/commerce/static/Rockland%20Ubiqu...
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Echelon Biosciences Inc. - Technology Development for Accelerated ...
Cheng, G. & Lambeth, J.D. NOXO1, regulation of lipid binding, localization, and activation of Nox1 by the Phox homology (PX) domain. J Biol Chem 279, ...
http://www.echelon-inc.com/commerce/misc/byear.jsp...
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Rockland 2006 4-74 Ver E
Immunogen: rec-NOXO1 corresponding to aa 238-252 of human. MW: 50 kDa ... NOXO1 protein. BLAST analysis was used to suggest cross ...
http://www.rockland-inc.com/commerce/static/Rockland%202006%...
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Part 2 3 2 06.qxp
NOXO1. IMX-3062. NPR2L. IMX-3614. NRBP/MADM. IMX-3637. NRL. IMX-4971. NRXN3. IMX -4972. Numb-like. IMX-3699. Nurim. IMX-5231. OLIG1. IMX-3778 ...
http://www.imgenex.com/dfiles/DownloadN-36.pdf...
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Abcam antibodies and reagents product map
... Mohawk homeobox antibodies (1) · NANOGP8 antibodies (1) · NKX2.8 antibodies (1) · NOXO1 antibodies (1) · Nkx3.1 antibodies (7) · ONECUT3 antibodies (1) ...
http://www.abcam.com/index.html?pageconfig=productmap&cl=345...
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Abcam antibodies and reagents product map
Products by type: Primary Antibodies · Secondary Antibodies · Isotype Controls · Loading Controls · Tags & Cell Markers · Proteins · Peptides · Kits ...
http://www.abcam.com/index.html?cl=2105&pageconfig=productma...
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