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ABCC2
| Symbol: | ABCC2 | | Name(s): | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | ABC30, CMOAT, DJS, KIAA1010, MRP2, cMRP | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18221820 |
Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 18294295 |
Observational study of gene-disease association, gene-gene interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 18334920 |
Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 17997497 |
we observed that haplotype frequency of the ABCC2 gene in intrahepatic cholestasis of pregnancy patients significantly differed from controls |
| 12960109 |
Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 15226675 |
Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 15519273 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15801936 |
Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 16041239 |
Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 16330681 |
Observational study of gene-disease association. (HuGE Navigator) | →View more information from publications. |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | Calnexin | ATP-binding cassette, sub-family C, member 2 | - | - | Pubmed |
| HPRD | calnexin precursor | ATP binding cassette, sub family C, member 2 | - | - | Pubmed |
| HPRD | ATP binding cassette, sub family C, member 2 | radixin | - | - | Pubmed |
| HPRD | ATP binding cassette, sub family C, member 2 | solute carrier family 9, isoform 3 regulator 1 | - | - | Pubmed |
| HPRD | ATP-binding cassette, sub-family C, member 2 | Radixin | - | - | Pubmed |
| HPRD | ATP-binding cassette, sub-family C, member 2 | Solute carrier family 9, isoform A3, regulatory factor 1 | - | - | Pubmed |
| HPRD | ATP-binding cassette, sub-family C, member 2 | PDZ domain containing 1 | - | - | Pubmed |
| HPRD | ATP-binding cassette, sub-family C, member 2 | PDZ domain containing 1 | - | - | Pubmed |
Recent Publications on ABCC2: |  |
Novel Large-scale Deletion (whole Exon 7) in the ABCC2 Gene in a Patient with the Dubin-Johnson Syndrome.
The Dubin-Johnson syndrome (DJS) is an inherited liver disorder... | 3rd November, 2009
| Department of Gastroenterology and Hepatology, Saiseikai Maebashi
| Drug Metab Pharmacokinet. 2009;24(5):464-8.
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Population Pharmacokinetics and Pharmacogenetics of Tacrolimus in De Novo Pediatric Kidney Transplant Recipients.
The aim of this study was to develop a population pharmacokinetic model of... | 30th October, 2009
| Department of Pediatric Pharmacology and Pharmacogenetics, Hopital Robert
| Clin Pharmacol Ther. 2009 Oct 28.
DOI Direct Link |
Multidrug resistance-associated protein 2 gene (ABCC2) variant in kidney allograft recipients.
Multidrug resistance-associated proteins may play crucial roles in the... | 28th October, 2009
| Department of Nephrology and Transplantation Medicine, Transplantation
| Transplant Proc. 2009 Oct;41(8):3009-10.
DOI Direct Link |
Involvement of drug transporters in the synergistic action of FOLFOX combination chemotherapy.
FOLFOX is a cytostatic drug combination for adjuvant treatment of... | 27th October, 2009
| Department of Internal Medicine VI, Clinical Pharmacology and
| Biochem Pharmacol. 2009 Dec 1;78(11):1366-73. Epub 2009 Jul 19.
DOI Direct Link |
Altered expression of MRP2, MRP3 and UGT2B1 in the liver affects the disposition of morphine and its glucuronide conjugate in a rat model of cholestasis.
OBJECTIVES: The aim was to investigate the disposition of morphine and... | 23rd October, 2009
| Laboratory of Clinical Pharmaceutics, Kobe Gakuin University, Kobe
| J Pharm Pharmacol. 2009 Sep;61(9):1205-10.
DOI Direct Link |
→View more research publications. |
ABCC2 results (if any) from reagent suppliers | 
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Anti-ABCC2 Monoclonal Antibody
Monoclonal Antibody against ABCC2 for use in Flow Cytometry, Immunocytochemistry , Immunohistochemistry (Paraffin, Frozen), Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...
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HPA004860 Anti-ABCC2 antibody produced in rabbit Prestige ...
HPA004860 Anti-ABCC2 antibody produced in rabbit Prestige Antibodies Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=HPA0...
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Anti-ABCC2 Monoclonal Antibody
Monoclonal Antibody against ABCC2 for use in Immunocytochemistry, Immunohistochemistry (Frozen)
http://www.bioreagents.com/products/productDetails/productDe...
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Antibodies to Drug Efflux Pumps
human ... ABCC2(1244) rat ... Abcc2(25303), rat, human, IF (i), WB, pricing ... human ... ABCC2(1244), human, ARR, ELISA (i), WB, pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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MRP2 (H-17) Antibody sc-5770
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ABCC2, 1244, 10q24.2, NM_000392 ...
http://www.scbt.com/datasheet-5770-mrp2-h-17-antibody.html...
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M3692 Monoclonal Anti-MRP2 antibody produced in mouse ~1.5 mg/mL ...
Synonym: Anti-ABCC2, Anti-cMOAT, Anti-cMRP, Anti-Multidrug Resistance Associated Protein 2 ... ABCC2(1244). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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Anti-CD105 Monoclonal Antibody
Monoclonal Antibody against CD105 for use in Flow Cytometry, Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...
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