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ADH5


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Symbol:ADH5
Name(s):alcohol dehydrogenase 5 (class III), chi polypeptide
Type:protein-coding
Organism:Homo sapiens
Synonyms:ADH-3, ADHX, FDH, GSNOR
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18331377 Observational study of gene-disease association. (HuGE Navigator)
16685648 Observational study of gene-disease association. (HuGE Navigator)
17185388 Observational study of gene-disease association. (HuGE Navigator)
17543375 Observational study of gene-disease association. (HuGE Navigator)
17543375 data suggest that genetic variation in S-nitrosoglutathione reductase (GSNOR) might play a role in asthma susceptibility
12004059 POZ domain of FBI1 represses transcription of ADH5.
12484756 Formation of a FDH-S-(hydroxymethyl)glutathione-NADH ternary complex causes movement of glutathione-dependent formaldehyde dehydrogenase catalytic domain toward the coenzyme-binding domain, and a change in active-site zinc coordination.
14608084 No evidence that alcohol dehydrogenase 3genotype modifies risk related to alcohol and lung cancer.
12196016 The structural determination of apo, binary alcohol, and inhibitory ternary FDH complexes provides new insight into the enzyme's metal-assisted catalysis and substrate-binding properties.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDclass III alcohol dehydrogenase 5 chi subunitclass III alcohol dehydrogenase 5 chi subunit--Pubmed

Recent Publications on ADH5:

Pubmed Logo
Inhibition of nitric oxide synthesis during induced cholestasis ameliorates hepatocellular injury by facilitating S-nitrosothiol homeostasis.
Cholestatic liver injury following extra- or intrahepatic bile duct...
7th October, 2009
Unidad de Investigacion del Hospital Universitario Reina Sofia, Instituto Lab Invest. 2009 Oct 5.
DOI Direct Link
Biofilm matrix regulation by Candida albicans Zap1.
A biofilm is a surface-associated population of microorganisms embedded in...
24th September, 2009
Department of Microbiology, Columbia University, New York, New York, PLoS Biol. 2009 Jun;7(6):e1000133. Epub 2009 Jun 16.
DOI Direct Link
Expression pattern, ethanol-metabolizing activities, and cellular localization of alcohol and aldehyde dehydrogenases in human pancreas: implications for pathogenesis of alcohol-induced pancreatic injury.
BACKGROUND: Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH)...
8th September, 2009
The Graduate Institute of Medical Sciences, and Department of Alcohol Clin Exp Res. 2009 Jun;33(6):1059-68. Epub 2009 Mar 23.
DOI Direct Link
Impaired uptake and/or utilization of leucine by Saccharomyces cerevisiae is suppressed by the SPT15-300 allele of the TATA-binding protein gene.
Successful fermentations to produce ethanol require microbial strains that...
12th August, 2009
Carlsberg Laboratory, DK-2500 Copenhagen Valby, Denmark. Appl Environ Microbiol. 2009 Oct;75(19):6055-61. Epub 2009 Aug 7.
DOI Direct Link
Associations of ADH and ALDH2 gene variation with self report alcohol reactions, consumption and dependence: an integrated analysis.
Alcohol dependence (AD) is a complex disorder with environmental and...
28th February, 2009
Genetic Epidemiology, Queensland Institute of Medical Research, Brisbane, Hum Mol Genet. 2009 Feb 1;18(3):580-93. Epub 2008 Nov 7.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
6986947 Method of modifying a fluoropolymer and articles thereby
6936417 Gene expression in bladder tumors
6867293 Polynucleotide constructs having at least one transcriptional enhancer and encoding a modified rice EPSPS enzyme
6858313 Multiple layer film with amorphous polyamide layer

View more patents.

ADH5 results (if any) from reagent suppliers

Google CSE Logo
ADH-5 (Breast Marker Cocktail)
ADH-5 Breast Marker Cocktail (Atypical Ductal Hyperplasia) is composed of ... Contact A Biocare Medical Sales Representative About ADH-5 (Breast Marker ...
http://www.biocare.net/antibodies/360DS.html...

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ADH5 antibodies: Signal Transduction > Metabolism > Alcohol ...
ADH5 antibodies. ... Image Abreview Publication. ab59134 · ADH5 antibody. WB. Customer Abreviews: 4 stars (out of 5). Goat polyclonal ...
http://www.abcam.com/index.html?t=237418&pt=1&c=3622&ei=&mu=...

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ADH-5 (Breast Marker Cocktail)
ADH-5 Breast Marker Cocktail (Atypical Ductal Hyperplasia) is composed of. CK5+ CK14+p63+CK7+CK18 antibodies. This cocktail can be used in a wide range ...
http://www.biocare.net/antibody-datasheets/360DS.pdf...

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ADH Antibody / ADH Antibodies
ADH5 (V-15) Antibody, sc-103375, goat IgG, Internal (h), WB, IF, ELISA, m, r, h, cow ... ADH5 shRNA (h) Lentiviral Particles: sc-105044-V ...
http://www.scbt.com/table-adh.html...

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Cancer Antibodies :: Page 3
Adenovirus-9 E4 Orf1 Antibody, 4749, V, E, Open reading frame 1 of the E4 region of Adenovirus 9. ADH5 Antibody, 45-207, H, M, R, D, E, ADH5 ...
http://www.prosci-inc.com/shop/catalog1/Cancer-Antibodies-p-...

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ADH5 siRNA (m) sc-105045
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: ADH5 ...
http://www.scbt.com/ko/datasheet-105045-adh5-sirna-m.html...

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Biocare Medical - Spring Forward - What's New in 2009
ADH-5 breast marker multiplex IHC is composed of CK5/14 + p63 + CK7/18 antibodies. ... ADH-5 can clearly differentiate hyperplasia of the usual type
from ...
http://www.biocare.net/biocare-new.html...

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