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ACVR1C


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Symbol:ACVR1C
Name(s):activin A receptor, type IC
Type:protein-coding
Organism:Homo sapiens
Synonyms:ACVRLK7, ALK7
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15107418 ALK7 induces apoptosis through activation of the traditional TGF-beta pathway components
12606401 ALK7 and its isoforms are expressed in human placentae of different stages of pregnancy and that their expression is developmentally regulated
15196700 AB and activin B and is responsible for activin-mediated secretion of insulin from pancreatic beta cell line, MIN6.
15150278 the Nodal-ALK7 pathway inhibits cell proliferation by inducing G(1) cell cycle arrest
16603637 ALK7-induced apoptosis is at least in part through two Smad-dependent pathways, Bax/Bcl-2 and Xiap.
12063393 cDNA cloning, expression studies and chromosome mapping

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDinhibin beta B subunit precursoractivin A receptor, type IC--Pubmed
HPRDTeratocarcinoma derived growth factor 1activin A receptor, type IC--Pubmed

Patents:

Patents logo
US Patent No.Title
7550300 Prediction of bare metal stent restenosis
7456149 ALK7 and myostatin inhibitors and uses thereof

ACVR1C results (if any) from reagent suppliers

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ACVR1C Antibody Activin A receptor type IC
ACVR1C antibody can be used for detection of ACVR1C by Western blot at 1 μg/ml.,
http://www.prosci-inc.com/shop/catalog1/ACVR1C-Antibody-p-67...

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Activin A Receptor Type IC (ACVR1C) Antibody (N-term A48)
Western blot analysis of anti-ACVR1C Antibody (N-term A48) (Cat.#AP7102a) in HepG2 and Hela cell line lysate (35ug/lane). ACVR1C (arrow) was detected using
...
http://www.abgent.com/products/catalog_no/AP7102a...

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ACVR1 Antibody Activin receptor-like kinase 2
Unlike ACVR1B and ACVR1C, ACVR1, also known as activin receptor-like kinase ... This antibody is predicted to have no cross-reactivity to ACVR1B or ACVR1C. ...
http://www.prosci-inc.com/shop/catalog1/ACVR1-Antibody-p-675...

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ACVR1C Antibody (Center E271)
Western blot analysis of anti-ACVR1C Antibody (Center) (Cat.#AP7102c) in Hela cell line lysates ... ACVR1C (arrow) was detected using the purified Pab. ...
http://www.abgent.com/products/catalog_no/AP7102c_ACVR1C_Ant...

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TGFβ RI (T-19) Antibody sc-402
Human, ACVR1C, 130399, 2q24.1, NM_001130916, NM_004612 · Q8NER5 · 608981. Mouse, Acvr1, 11477, 2 C1.1, NM_009370 · P37172 ...
http://www.scbt.com/datasheet-402-tgfbeta-ri-t-19-antibody.h...

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Abgent - Phosphorylation Antibodies - Phosphorylation
AP7102cNEW, ACVR1C Antibody (Center E271), WB, E, H .... AP7102b, Activin A Receptor Type IC (ACVR1C) Antibody (Center), WB, E, H, M ...
http://www.abgent.com/products/category/protein_modification...

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Signal Transduction Antibodies :: Page 2
ACVR1B Antibody, 4793, H, M, E, WB, Activin A receptor type IB. ACVR1C Antibody, 4795, H, M, R, E, WB, Activin A receptor type IC ...
http://www.prosci-inc.com/shop/catalog1/Signal-Transduction-...

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Cyclin G2 is degraded through the ubiquitin-proteasome pathway and mediates the antiproliferative effect of activin receptor-like kinase 7. Mol Biol Cell, 2008 19(11) p. 4968-79 | ACVR1C disease | mouse acvr1c beta cell | acvr1c beta cell | acvr1c beta cells | ACVR1C adipose tissue | .


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