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ADM


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Gene DB Home
Symbol:ADM
Name(s):adrenomedullin
Type:protein-coding
Organism:Homo sapiens
Synonyms:AM
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11463752 Observational study of gene-disease association. (HuGE Navigator)
12753312 Observational study of gene-disease association. (HuGE Navigator)
16097366 Observational study of gene-disease association. (HuGE Navigator)
16609682 Observational study of gene-disease association. (HuGE Navigator)
17922433 Observational study of gene-disease association. (HuGE Navigator)
17941085 These data show that ADM acts as a survival factor in osteoblastic cells via a CGRP1 receptor-MEK-ERK pathway, which provides further understanding on the physiological function of ADM in osteoblasts.
18080871 Depending on the clinical severity of the infection, both CT-proET-1 and MR-proADM levels exhibited a gradual increase from Systemic Inflammatory Response Syndrome (SIRS) to sepsis and septic shock.
17766467 In conclusion, ADM exerts Ca(2+)-dependent positive inotropic effects in human atrial and less-pronounced effects in ventricular myocardium.
18000597 possesses several protective cardiovascular qualities, including protection of the microcirculation during inflammation, and was proven as an efficient counter-regulatory molecule in various models of sepsis and septic shock.
17952853 Adrenomedullin (ADM) expression in the anterior pituitary is diminished in tumors as compared to the normal gland.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDAdrenomedullinG protein-coupled receptor 182--Pubmed
HPRDadrenomedullinAdrenomedullin receptor--Pubmed
HPRDadrenomedullincomplement factor H--Pubmed
HPRDadrenomedullincomplement factor H--Pubmed
HPRDadrenomedullinendothelin 1--Pubmed
HPRDadrenomedullinendothelin 1--Pubmed
HPRDadrenomedullincalcitonin receptor-like--Pubmed
HPRDadrenomedullinnatriuretic peptide precursor C--Pubmed
HPRDadrenomedullinnatriuretic peptide precursor C--Pubmed

Recent Publications on ADM:

Pubmed Logo
[Screening the differential expression of adriamycin-resistance related genes of breast cancer by cDNA microarray]
OBJECTIVE :To study the differential gene expression of...
30th October, 2009
Department of General Surgery Oncology, General Coal Hospital, Beijing Zhonghua Yi Xue Za Zhi. 2009 Jul 7;89(25):1745-8.
[The relationship between multi-drug resistance and proportion of leukemia stem cells and expression of drug transporters in drug-resistant leukemia K562/ADM cells]
OBJECTIVE: To investigate the drug resistance, proportion of leukemia stem...
30th October, 2009
Laboratory Center for Medical Science, School of Medicine, Lanzhou Zhonghua Yi Xue Za Zhi. 2009 Jul 7;89(25):1741-4.
Regulation of the Histone Demethylase JMJD1A by HIF-1{alpha} Enhances Hypoxic Gene Expression and Tumor Growth.
The hypoxia-inducible transcription factors (HIFs) directly and indirectly...
28th October, 2009
Division of Radiation and Cancer Biology, Department of Radiation Mol Cell Biol. 2009 Oct 26.
DOI Direct Link
Children with lethal streptococcal fasciitis after a minor contusion injury.
Necrotizing fasciitis is a severe life-threatening soft tissue infection...
28th October, 2009
Department of Emergency Medicine, Chang Gung Memorial Hospital and Chang Am J Emerg Med. 2009 Oct;27(8):1017.e3-5.
DOI Direct Link
The incidence and risk of developing a second primary esophageal cancer in patients with oral and pharyngeal carcinoma: a population-based study in Taiwan over a 25 year period.
BACKGROUND: The incidence of oral and pharyngeal (including oral cavity,...
22nd October, 2009
Department of Hematology, Chang Gung Memorial Hospital at Chiayi, Taiwan, BMC Cancer. 2009 Oct 20;9:373.
DOI Direct Link

View more research publications.

Press Releases on ADM:

BioPortfolio Logo
TCS Revenues Cross $3 Billion in H1 on Strong Operational Performance 22nd October, 2008 Tata Consultancy Services

MUMBAI, India, Oct. 22 /PRNewswire/ -- Tata Consultancy Services (BSE: TCS.BO, NSE: TCS.NS) reported its consolidated financial results according to US GAAP for the quarter ended September 30,

Mom with Diabetes Invents Device to Make Insulin Injections Easier 9th September, 2008 Patton Medical Devices

AUSTIN, Texas, Sept. 9 /PRNewswire/ -- When KK Patton was prescribed multiple daily insulin injections to treat her diabetes in 2001, the Austin, Texas Mom discovered she didn't like the

SectorWatch.biz Issues MarketStats on Agri-Biotech Equities YGYB, GRO, SEED, MON, ADM, and BG 9th September, 2008 SectorWatch.biz

IRVINE, Calif., Sept. 9 /PRNewswire/ -- SectorWatch.biz announces the availability of MarketStats for agri-biotech equities in the news and driving markets today. MarketStats offers a

New Survey Explores the Impact of Insulin Injections and Communications Between Patients and Healthcare Providers 7th August, 2008 The American Association of Diabetes Educators

CHICAGO, Aug. 7 /PRNewswire/ -- The American Association of Diabetes Educators (AADE) today announced results from a survey conducted by Harris Interactive highlighting communication between

Two-Thirds of Healthcare Professionals Polled Attribute Improved Patient Self-Management to the U.S. Diabetes Conversation Map(R) Program 4th June, 2008 Healthy Interactions

SAN FRANCISCO, June 4 /PRNewswire/ -- New research shows 65 percent of participating healthcare professionals resoundingly said they can attribute improved patient self-management to the U.S.

BioNews Results for ADM

: RSS Logo
BioPortfolio Logo
Forum speakers note gaps in vets' mental health care
SoMdNews.com:  Nov 14 2009 2:33PM Matching: adm
BioTrove Inc. Announces Formation of Subsidiary
Pharma Live:  Nov 11 2009 9:56PM Matching: adm
Life Technologies Acquires BioTrove to Bolster PCR Business
Genetic Engineering News:  Nov 11 2009 12:27AM Matching: adm
BioTrove Inc. Announces Formation of Subsidiary
Genetic Engineering News:  Nov 10 2009 3:59PM Matching: adm
New ADME LIMS Release Makes Protein Binding Easier
CombiChemnet:  Nov 8 2009 1:25PM Matching: adm
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Study of DOXIL/CAELYX (Pegylated Liposomal Doxorubicin) and VELCADE (Bortezomib) or VELCADE Monotherapy for the Treatment of Relapsed Multiple Myeloma

Patents:

Patents logo
US Patent No.Title
7582635 Therapeutic agents useful for treating pain
7590153 Protocol independent sub-rate device
7590964 Method and system for automatic generation of processor datapaths using instruction set architecture implementing means
7592028 Compositions and processes for making high soy protein-containing bakery products
7592177 Compositions and methods for inducing cell dedifferentiation

View more patents.

ADM results (if any) from reagent suppliers

Google CSE Logo
ADM (HTA171/E8) Antibody sc-53153
ADM shRNA (h) Lentiviral Particles, sc-39273-V, 200 µl ... ADM (HTA171/E8): sc- 53153. Immunoperoxidase staining of formalin fixed, paraffin-embedded human ...
http://www.scbt.com/datasheet-53153-adm-hta171-e8-antibody.h...

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Adrenomedullin and PAMP
Adrenomedullin (ADM) eloquently fits this ancient wisdom. Hypotensive effects are elicited by fragments of ADM retaining the C-terminal with ring structure.
...
http://www.phoenixpeptide.com/catalog/pnxfoget.php?id=pnxnew...

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ADM (FL-185) Antibody sc-33187
rabbit polyclonal IgG, 200µg/ml; epitope corresponding to amino acids 1-185 representing full length ADM of human origin; recommended for detection of ...
http://www.scbt.com/datasheet-33187-adm-fl-185-antibody.html...

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Sample Preparation - Phoenix Peptides
ADM protein levels from plasma and organs: Blood samples were collected in a centrifuge tube (stabilized with EDTA) and, after centrifugation, ...
http://www.phoenixpeptide.com/catalog/pnxfoget.php?id=pnxhig...

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ADM (027-01-1) Antibody sc-80462
ADM shRNA (h) Lentiviral Particles, sc-39273-V, 200 µl ... ADM (027-01-1): sc- 80462. Western blot analysis of human recombinant ADM. Download ...
http://www.scbt.com/datasheet-80462-adm-027-01-1-antibody.ht...

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PHOENIX PHARMACEUTICALS, INC. Obesity
ADM-Pro-N-20. A3,B3. Endorphin Beta. A9,B9. Leptin. G5,H5. PrRP-31. G3,H3. ADM ( 1-50) ... ADM (1-50). A4,B4. Ghrelin. C8,D8. Leptin. G5,H5. Peptide YY ...
http://www.phoenixpeptide.com/catalog/index.php?cPath=70_75...

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ADM Receptor (P-20) Antibody sc-16500
goat polyclonal IgG, 200 µg/ml; epitope mapping at the N-terminus of ADM Receptor of mouse origin; recommended for detection of ADM receptor of m and r
...
http://www.scbt.com/datasheet-16500-adm-receptor-p-20-antibo...

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