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CLDN4
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18251778 |
Cdx2 plays an important role in the regulation of intestinal claudin expression not only in gastric mucosa with intestinal metaplasia but also gastric carcinoma. |
| 18283635 |
MMP-2, MMP-9 and claudin-4 expression may be phenotypic features, distinguishing intestinal-type and diffuse-type gastric cancer. |
| 17678893 |
The modulation of claudin-4 activity by PKCepsilon may not only provide a mechanism for disrupting TJ function in ovarian cancer, but may also be important in the regulation of TJ function in normal epithelial cells. |
| 17709988 |
vinculin plays a role in growth regulation of neuroendocrine tumors and in expression of CLD4 |
| 17418912 |
When compared, small-cell-lung cancers and carcinoid tumors, adenocarcinomas, and squamous cell carcinomas in CLDN4 expression. |
| 17459057 |
Loss of claudin expression may enhance the grade of malignancy of gastric cancer in vivo. |
| 17651017 |
Our data suggest that JUND and CLDN4 are critical mediators of the antiproliferative and antiviral effects of type I IFNs and further confirm the functional importance of the DNA-binding domain of Stat2. |
| 15643498 |
claudin 4 may play a role in the disruption of cell-to-cell adhesion in diffuse type gastric cancer and in a loss of differentiation. |
| 17545541 |
Claudin-3 and claudin-4 receptors are highly overexpressed in carcinosarcoma |
| 17359339 |
Tight junction proteins contribute to the permeability barrier in epidermal keratinocytes | →View more information from publications. |
Recent Publications on CLDN4: |  |
Molecular characterization of cultured adult human liver progenitor cells.
Hepatic progenitor cells hold great promise as a self-renewing cell source... | 31st October, 2009
| Max Planck Institute for Molecular Genetics, Vertebrate Genomics,
| Tissue Eng Part C Methods. 2009 Oct 29.
DOI Direct Link |
Recombinant CPE fused to tumor necrosis factor targets human ovarian cancer cells expressing the claudin-3 and claudin-4 receptors.
Using gene expression profiling, others and we have recently found that... | 20th October, 2009
| Department of Medicine and the Rebecca and John Moores University of
| Mol Cancer Ther. 2009 Jul;8(7):1906-15. Epub 2009 Jun 30.
DOI Direct Link |
TNFR and LTbetaR agonists induce follicle-associated epithelium and M cell specific genes in rat and human intestinal epithelial cells.
M cells assist mucosal immune surveillance by transcytosis of particles to... | 22nd September, 2009
| Division of Biomedical Sciences, University of California, Riverside, CA
| Cytokine. 2009 Jul;47(1):69-76. Epub 2009 Jun 5.
DOI Direct Link |
Therapeutic antitumor efficacy of monoclonal antibody against Claudin-4 for pancreatic and ovarian cancers.
Claudin-4 (CLDN4) is a tetraspanin transmembrane protein of tight junction... | 11th September, 2009
| Antibody Research Laboratories, Kyowa Hakko Kirin Co., Ltd, Machida-shi,
| Cancer Sci. 2009 Sep;100(9):1623-30. Epub 2009 Jun 1.
DOI Direct Link |
Expression of tight junction protein claudin-4 in basal-like breast carcinomas.
Claudins (CLDN) are tight junction proteins which contribute to the... | 21st August, 2009
| 2nd Department of Pathology, Semmelweis University, 93 Ulloi ut, 1091,
| Pathol Oncol Res. 2009 Mar;15(1):59-64. Epub 2008 Aug 28.
DOI Direct Link |
→View more research publications. |
CLDN4 results (if any) from reagent suppliers | 
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claudin-4 (C-18) Antibody sc-17664
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, CLDN4, 1364, 7q11.23, NM_001305 ...
http://www.scbt.com/datasheet-17664-claudin-4-c-18-antibody....
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Abgent - Cell and Function Antibodies
AT1552aNEW, CLDN20 monoclonal antibody (M01), ELISA,S-ELISA, H. AT1553aNEW, CLDN4 monoclonal antibody (M01), ELISA,IHC-P,WB-Re, H ...
http://www.abgent.com/products/category/cell_function...
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claudin-3/4/6/9 (FL-209) Antibody sc-28666
Mouse, Cldn4, 12740, 5 G2, O35054, N/A. Mouse, Cldn6, 54419, 17 A3.3, Q9Z262, N/ A. Mouse, Cldn9, 56863, 17 A3.3, Q9Z0S7 ...
http://www.scbt.com/datasheet-28666-claudin-3-4-6-9-fl-209-a...
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claudin-4 siRNA (m) sc-35071
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Cldn4, 12740, 5 G2, O35054 ...
http://www.scbt.com/datasheet-35071-claudin-4-sirna-m.html...
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