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CLDN3
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18251778 |
Cdx2 plays an important role in the regulation of intestinal claudin expression not only in gastric mucosa with intestinal metaplasia but also gastric carcinoma. |
| 16627685 |
The gene expression profile of hepatic stem cells throughout life consists of high levels of expression of claudin-3 (CLDN-3). |
| 17418912 |
When compared, small-cell-lung cancers, carcinoid tumors, and adenocarcinomas revealed significant differences re: CLDN3 expression. |
| 17459057 |
Loss of claudin expression may enhance the grade of malignancy of gastric cancer in vivo. |
| 17647191 |
CLDN3 overexpression can be used as a prognostic indicator in ovarian serous carcinomas and it may be a promising target for antibody-based therapy of ovarian carcinomas. |
| 17545541 |
Claudin-3 and claudin-4 receptors are highly overexpressed in carcinosarcoma |
| 12909588 |
Airway tight junctions are regulated by claudin interactions that confer the selectivity of the junction. |
| 17103306 |
Claudin tight junction proteins in endoscopy biopsy samples showed Barrett's metaplasia contains more claudin-2 and claudin-3 than found in normal esophageal mucosa, but markedly lower claudins 1 and 5, indicating very different tight junction barriers. |
| 17326053 |
Overexpression of claudin-3 is associated with uterine serous papillary carcinoma |
| 16253248 |
The expression of claudin-1, -3 and -4 was upregulated 5.7-, 1.5- and 2.4-fold, respectively, in colorectal tumor tissues in comparison to the normal ones. | →View more information from publications. |
Recent Publications on CLDN3: |  |
Recombinant CPE fused to tumor necrosis factor targets human ovarian cancer cells expressing the claudin-3 and claudin-4 receptors.
Using gene expression profiling, others and we have recently found that... | 20th October, 2009
| Department of Medicine and the Rebecca and John Moores University of
| Mol Cancer Ther. 2009 Jul;8(7):1906-15. Epub 2009 Jun 30.
DOI Direct Link |
Therapeutic antitumor efficacy of monoclonal antibody against Claudin-4 for pancreatic and ovarian cancers.
Claudin-4 (CLDN4) is a tetraspanin transmembrane protein of tight junction... | 11th September, 2009
| Antibody Research Laboratories, Kyowa Hakko Kirin Co., Ltd, Machida-shi,
| Cancer Sci. 2009 Sep;100(9):1623-30. Epub 2009 Jun 1.
DOI Direct Link |
Epstein-Barr virus-associated gastric carcinoma: a distinct carcinoma of gastric phenotype by claudin expression profiling.
Epstein-Barr virus (EBV)-associated gastric carcinoma (GC) is a distinct... | 1st September, 2009
| Department of Pathology, Graduate School of Medicine, The University of
| J Histochem Cytochem. 2009 Aug;57(8):775-85. Epub 2009 Apr 27.
DOI Direct Link |
Development and characterization of a human single-chain antibody fragment against claudin-3: a novel therapeutic target in ovarian and uterine carcinomas.
OBJECTIVE: The purpose of this study was to develop and characterize a... | 22nd August, 2009
| Department of Obstetrics and Gynecology, Division of Gynecologic Oncology,
| Am J Obstet Gynecol. 2009 Jul;201(1):70.e1-9. Epub 2009 May 8.
DOI Direct Link |
Microarray analysis of RNA extracted from formalin-fixed, paraffin-embedded and matched fresh-frozen ovarian adenocarcinomas.
ABSTRACT: BACKGROUND: Gene expression profiling of formalin-fixed,... | 12th May, 2009
| Department of Molecular Biology, Genentech, Inc,, 1 DNA Way, South San
| BMC Med Genomics. 2009 May 8;2:23.
DOI Direct Link |
→View more research publications. |
CLDN3 results (if any) from reagent suppliers | 
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claudin-3 (M-20) Antibody sc-17662
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, CLDN3, 1365, 7q11.23, NM_001306 ...
http://www.scbt.com/datasheet-17662-claudin-3-m-20-antibody....
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PhosphoSignature™
CLDN3. Claudin-3 (CPE-receptor 2) (HRVP1). O15551. 23. 219. STGPGASLGTGYDRKDyV. 3. 66. 9.3. 9.0-9.5. CFL1. Cofilin-1 (Cofilin, non-muscle) ...
http://www.cellsignal.com/technologies/phosphoscan/pdfs/PSig...
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claudin-3/4/6/9 (FL-209) Antibody sc-28666
Mouse, Cldn3, 12739, 5 G2, Q9Z0G9, N/A. Mouse, Cldn4, 12740, 5 G2, O35054, N/A. Mouse, Cldn6, 54419, 17 A3.3, Q9Z262 ...
http://www.scbt.com/datasheet-28666-claudin-3-4-6-9-fl-209-a...
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claudin-3 siRNA (m) sc-43043
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Cldn3, 12739, 5 G2, Q9Z0G9 ...
http://www.scbt.com/datasheet-43043-claudin-3-sirna-m.html...
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