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CRH


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Symbol:CRH
Name(s):corticotropin releasing hormone
Type:protein-coding
Organism:Homo sapiens
Synonyms:CRF
Links: Pubmed, Entrez Gene, GeneCards, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12734882 Observational study of gene-disease association. (HuGE Navigator)
14573312 Observational study of gene-disease association. (HuGE Navigator)
11140838 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
11555839 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
12051390 Observational study of gene-disease association. (HuGE Navigator)
12154211 Observational study of gene-disease association. (HuGE Navigator)
17676473 Network analysis showed that AA have retained an ancestral CRH haplotype, while the most common EA haplotype is derived from a single recombination event.
18212352 phorbol ester stimulates CRH gene transcriptional activity through the CRE, suggesting that cross-talk between PKC and protein kinase A signaling pathways targets this regulatory element in placental cells
17693031 Acute GES reduces the number of CRF-producing neurons and decreases CRF expression in PVN during post-operative gastric ileus.
17568667 findings suggest that CRH augments LPS induced cytokine secretion in human trophoblast cells. Modulation of LPS induced immune responses by CRH may be mediated through regulation of TLR-4 and selective activation of the p38/MAPK signalling pathway.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCorticotropin releasing hormoneHomo sapiens corticotropin releasing hormone receptor type 2 beta isoform mRNA, complete cds.--Pubmed
HPRDcorticotropin releasing hormone precursorCorticotropin releasing hormone receptor 2--Pubmed
HPRDcorticotropin releasing hormone precursorcorticotropin releasing hormone receptor 1--Pubmed
HPRDcorticotropin releasing hormone precursorcorticotropin releasing hormone receptor 1--Pubmed

Recent Publications on CRH:

Pubmed Logo
Common Genetic Origins for EEG, Alcoholism and Anxiety: The Role of CRH-BP.
The resting EEG is a dynamic index of cortical activation, cognitive...
1st November, 2008
Laboratory of Neurogenetics, National Institute on Alcohol Abuse and PLoS ONE. 2008;3(10):e3620. Epub 2008 Oct 31.
DOI Direct Link
Involvement of CRH-R2 receptor in eating behavior and in the response of the HPT axis in rats subjected to dehydration-induced anorexia.
Wistar rats subjected to dehydration-induced anorexia (DIA), with 2.5%...
28th October, 2008
Division de Investigaciones en Neurociencias, Instituto Nacional de Psychoneuroendocrinology. 2008 Oct 23.
DOI Direct Link
Adiponectin depolarizes parvocellular paraventricular nucleus neurons controlling neuroendocrine and autonomic function.
Adiponectin plays important roles in the control of energy homeostasis and...
25th October, 2008
Department of Physiology, Queen's University, Kingston, Ontario, Canada Endocrinology. 2008 Oct 23.
DOI Direct Link
[Sindromi paraneoplastiche correlate a tumori dell'apparato uro-genitale: rassegna d'aggiornamento.]
Versione italiana Le sindromi paraneoplastiche indotte da produzione...
25th October, 2008
G Chir. 2008 Oct;29(10):437-48.
Does obesity play a major role in the pathogenesis of sleep apnoea and its associated manifestations via inflammation, visceral adiposity, and insulin resistance?
Despite the early recognition of the strong association between...
24th October, 2008
Department of Psychiatry, Sleep Research and Treatment Center, Hershey, PA Arch Physiol Biochem. 2008 Oct;114(4):211-23.
DOI Direct Link

View more research publications.

BioNews Results for CRH

: RSS Logo
BioPortfolio Logo
Hypoadrenocorticism in the dog (Proceedings)
Thomson Veterinary Healthcare Communications:  Nov 4 2008 4:02AM Matching: crh
Friday Newspaper Review - Irish Business News and International
Today's Medical Developments:  Oct 31 2008 8:01AM Matching: crh
DIARY - Western European Corporate events from Oct 30, 2008
Forbes.com:  Oct 30 2008 6:38AM Matching: crh
DIARY - Western European Corporate events from Oct 30, 2008
FinanzNachrichten.de:  Oct 30 2008 6:29AM Matching: crh
DIARY - Western European Corporate events from Oct 29, 2008
Interactive Investor International:  Oct 28 2008 5:39AM Matching: crh
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Dose Response Relationship for Single Doses of Corticotropin Releasing Hormone (CRH) in Normal Volunteers and in Patients With Adrenal Insufficiency
Adrenal Gland Hyperfunction;   Adrenal Gland Hypofunction;   Cushing's Syndrome;   Healthy

Patents:

Patents logo
US Patent No.Title
7267939 Detection of analytes using reorganization energy
7304081 Amido compounds and their use as pharmaceuticals
7307082 Heterocyclic derivatives as CRF antagonists
7309348 Method for treatment of depression
7312087 Devices and methods for biochip multiplexing

View more patents.

CRH results (if any) from reagent suppliers

Google CSE Logo
WH0001392M2 Monoclonal Anti CRH antibody produced in mouse clone ...
WH0001392M2 Monoclonal Anti-CRH antibody produced in mouse clone 2B11, purified immunoglobulin, buffered aqueous solution.
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...

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GTX100193-CRHR2 antibody-GeneTex Inc.
Corticotropin-releasing hormone (CRH; 122560) is a 41-amino acid peptide synthesized in ... It shows high-affinity CRH binding and also binds to
urocortin. ...
http://www.genetex.com/commerce/catalog/product.jsp;jsession...

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CRH corticotropin releasing hormone
CRH; CRF. Refseq ID(s). NM_000756. Accession No.(s) ... WH0001392M2, Monoclonal Anti-CRH antibody produced in mouse clone 2B11, purified immunoglobulin, ...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...

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DVANCED ARGETING YSTEMS
Antibody to Corticotropin Releasing Hormone/Factor (CRH/CRF). RABBIT POLYCLONAL. 11175-A FLINTKOTE AVENUE, SAN DIEGO, CA 92121 ...
http://www.atsbio.com/catalog/data/ab02.pdf...

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Antibodies to Neuropeptides
Crh(81648), human, rat, mouse, pig, canine, frog, sheep, bovine, ARR, IHC (p), RIA. E1520, Anti-β-Endorphin antibody produced in rabbit, whole antiserum ...
http://www.sigmaaldrich.com/catalog/search/TablePage/9676517...

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CRF (S-19) Antibody sc-1761
Regulation of the hypothalamic-pituitary-adrenocortical system in mice deficient for CRH receptors 1 and 2. Endocrinology. 142: 4946-4955. View PubMed Entry ...
http://www.scbt.com/datasheet-1761-crf-s-19-antibody.html...

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XP725 Panorama Antibody Microarray XPRESS Profiler725 Kit
... Cnn1(12797), Cnn2(12798), Cnp(12799), Cops5(26754), Crh(12918), Crk(12928), Crkl(12929), Csk(12988), Csnk2a1(12995), Csnk2b(13001), Ctbp1(13016), ...
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...

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CRF (H-104) Antibody sc-10718
Accession #, OMIM™ Number. Human, CRH, 1392, 8q13.1, NM_000756 · P06850 · 201400 . Mouse, Crh, 12918, 3 A2, Q8CIT0, N/A. Ordering Information ...
http://www.scbt.com/datasheet-10718-crf-h-104-antibody.html...

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'It's All Good' During 2006-07 Season At Hancher Auditorium ...
7 Apr 2006 ... 3 SUNDAY -- The Western Wind, "The Chanukah Story," 2 pm, CRH ... 23 FRIDAY -- Stuttgart Chamber Orchestra with Leon Fleisher, CRH ...
http://www.uiowa.edu/~ournews/2006/april/040706hancher_seaso...

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Antibody Details (ATS)
Corticotropin Releasing Hormone (CRH/CRF) Rabbit Polyclonal (Cat. #AB-02, 100 µl ). Specificity & Preparation: This antibody recognizes human and rat ...
http://www.atsbio.com/catalog/antibodies/abinfo.html...

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