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CRHR1


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Symbol:CRHR1
Name(s):corticotropin releasing hormone receptor 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:CRF-R, CRF1, CRFR1, CRH-R1h, CRHR, CRHR1f
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18250257 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
14724656 Observational study of gene-disease association. (HuGE Navigator)
15128701 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15203442 Observational study of gene-disease association. (HuGE Navigator)
15293277 Observational study of gene-disease association. (HuGE Navigator)
15365580 Clinical trial of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15992556 Observational study of gene-disease association. (HuGE Navigator)
16113459 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16415175 Observational study of gene-disease association. (HuGE Navigator)
16550213 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDcalmodulin 1corticotropin releasing hormone receptor 1Calmodulin interacts with CRF1R.-Pubmed
HPRDcorticotropin releasing hormone precursorcorticotropin releasing hormone receptor 1--Pubmed
HPRDcorticotropin releasing hormone precursorcorticotropin releasing hormone receptor 1--Pubmed
HPRDCorticotropin releasing hormone receptor 1guanine nucleotide binding protein, alpha inhibiting activity polypeptide 1--Pubmed
HPRDCorticotropin releasing hormone receptor 1guanine nucleotide binding protein, q polypeptide--Pubmed
HPRDCorticotropin releasing hormone receptor 1guanine nucleotide binding protein, alpha activating polypeptide O isoform a--Pubmed
HPRDCorticotropin releasing hormone receptor 1guanine nucleotide binding protein, alpha stimulating activity polypeptide 1 isoform c--Pubmed
HPRDcorticotropin releasing hormone receptor 1G protein, alpha inhibiting 1--Pubmed
HPRDcorticotropin releasing hormone receptor 1Guanine nucleotide binding protein G(q) alpha subunit--Pubmed
HPRDcorticotropin releasing hormone receptor 1Guanine nucleotide binding protein G(S), alpha subunit--Pubmed

Recent Publications on CRHR1:

Pubmed Logo
H2 haplotype at chromosome 17q21.31 protects against childhood sexual abuse-associated risk for alcohol consumption and dependence.
ABSTRACT Animal research supports a central role for...
3rd November, 2009
Department of Psychiatry, Washington University School of Medicine, USA. Addict Biol. 2009 Oct 29.
DOI Direct Link
Heterogeneity of response to asthma controller therapy: clinical implications.
PURPOSE OF REVIEW: Patients with asthma exhibit heterogeneous responses to...
31st October, 2009
National Jewish Health, Denver, and the University of Colorado Denver Curr Opin Pulm Med. 2009 Oct 28.
DOI Direct Link
Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans.
We studied seven genes that reflect events relevant to antidepressant...
22nd October, 2009
Department of Psychiatry and Behavioral Sciences, Center for Mol Psychiatry. 2009 Oct 20.
DOI Direct Link
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies.
Bone mineral density (BMD) is a heritable complex trait used in the...
6th October, 2009
Department of Internal Medicine, Rotterdam, The Netherlands. Nat Genet. 2009 Nov;41(11):1199-206. Epub 2009 Oct 4.
DOI Direct Link
Phenotypic expansion and further characterisation of the 17q21.31 microdeletion syndrome.
BACKGROUND: The recognition of the 17q21.31 microdeletion syndrome has...
24th September, 2009
J Med Genet. 2009 Jul;46(7):480-9. Epub 2009 May 15.
DOI Direct Link

View more research publications.

Press Releases on CRHR1:

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Advances in the development of corticotropin-releasing-hormone (CRH) 1st January, 1970 Dailyupdates

BioNews Results for CRHR1

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Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans
Molecular Psychiatry Journal:  Oct 20 2009 4:57PM Matching: crhr1

Clinical Trials:

Clinical Trials Logo
Gender and Neural Substrates of Stress and Craving

Patents:

Patents logo
US Patent No.Title
7608406 Diagnostic markers of stroke and cerebral injury and methods of use thereof
5976807 Eukaryotic cells stably expressing genes from multiple transfected episomes
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

View more patents.

CRHR1 results (if any) from reagent suppliers

Google CSE Logo
Human CRHR-1 Phycoerythrin MAb (Clone 343919)
CRHR-1: Contains 1.0 mL of PE-labeled antibody at a concentration of 25 μg/mL. ... cells bearing CRHR-1 within a population and qualitatively ...
http://www.rndsystems.com/pdf/FAB3930P.pdf...

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CRF-RI (V-14) Antibody sc-12381
Corticotropin-Releasing Hormone Receptor (CRHR)1 and CRHR2 Are Both Trafficking and Signaling Receptors for Urocortin. Mol. Endocrinol. 21: 700-711. ...
http://www.scbt.com/datasheet-12381-crf-ri-v-14-antibody.htm...

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monoclonal antibody template
97% amino acid sequence identity with mouse and rat CRHR-1. ... This antibody detects CRHR-1 transfectants but not irrelevant transfectants. Applications ...
http://www.rndsystems.com/pdf/MAB3930.pdf...

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CRF-RI (Q-20) Antibody sc-12383
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, CRHR1, 1394, 17q21.31, NM_004382 ...
http://www.scbt.com/datasheet-12383-crf-ri-q-20-antibody.htm...

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Imgenex : GPCR Antibodies: Class B Secretin-like
IMG-71242, Corticotropin releasing factor, Corticotropin-Releasing Factor Receptor 1 (CRHR1), Rabbit, pAb, H, IHC-P, 0.05 mg ...
http://imgenex.com/view_data_page.php?id=89...

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MembraneMax™ Protein Expression kits
CRHR1 (NM_004382), 0.30. MGST2 (NM_002413.3), 0.30. Glycophorin E (NM_002102.2), 0.30. MGST2 (NM_004528.2), 0.30. Epiregulin (NM_001432.1), 0.30 ...
http://www.invitrogen.com/site/us/en/home/Products-and-Servi...

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Sept 07 NPR_No prices.indd
CRHR-1. Human. 343919. MAB3930. 100 µg. CXCR4. Feline. 374606. MAB4287. 100 µg. Cyclin D1. Human. 328303. MAB4314. 100 µg. DARC. Human. 358307. MAB4139 ...
http://www.rndsystems.com/DAM_public/5933.pdf...

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