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HAPLN1


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Symbol:HAPLN1
Name(s):hyaluronan and proteoglycan link protein 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:CRTL1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15456769 SOX9 is a key regulator of CRTL1
14724283 link protein may function as a stabilizer of the interaction between aggrecan and hyaluronan in cartilage and between versican and hyaluronan in many tissues
15590670 cLP and versican did not bind directly to each other in solution yet formed ternary complexes with hyaluronan

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDaggrecan 1 isoform 2 precursorhyaluronan and proteoglycan link protein 1--Pubmed
HPRDaggrecan 1 isoform 2 precursorhyaluronan and proteoglycan link protein 1--Pubmed
HPRDhyaluronan and proteoglycan link protein 1versican--Pubmed
HPRDhyaluronan and proteoglycan link protein 1versican--Pubmed

Recent Publications on HAPLN1:

Pubmed Logo
Glypican 5 is an interferon-beta response gene: a replication study.
BACKGROUND: Multiple sclerosis (MS) is a chronic inflammatory disease of...
9th October, 2009
Clinical Immunology Department, Hospital Clinico San Carlos, Madrid, Mult Scler. 2009 Aug;15(8):913-7. Epub 2009 Jun 25.
DOI Direct Link
Egr-1 inhibits the expression of extracellular matrix genes in chondrocytes by TNFalpha-induced MEK/ERK signalling.
INTRODUCTION: TNFalpha is increased in the synovial fluid of patients with...
10th September, 2009
Canadian Institutes of Health Research Group in Skeletal Development and Arthritis Res Ther. 2009;11(1):R8. Epub 2009 Jan 14.
DOI Direct Link
Oral cancer cells with different potential of lymphatic metastasis displayed distinct biologic behaviors and gene expression profiles.
Objective: Oral squamous cell carcinoma (OSCC) often spreads from the...
15th August, 2009
State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, J Oral Pathol Med. 2009 Aug 12.
DOI Direct Link
Protumorigenic role of HAPLN1 and its IgV domain in malignant pleural mesothelioma.
PURPOSE: Tumor extracellular matrix (ECM) plays a crucial role in cancer...
6th June, 2009
Department of Cardiothoracic Surgery, Langone School of Medicine, New York Clin Cancer Res. 2009 Apr 15;15(8):2602-11. Epub 2009 Apr 7.
DOI Direct Link
Molecular cloning and developmental expression of a hyaluronan and proteoglycan link protein gene, crtl1/hapln1, in zebrafish.
The proteoglycan aggregate of the cartilage is composed of aggrecan, link...
15th April, 2009
Department of Molecular Biology and Biochemistry, Okayama University Zoolog Sci. 2008 Sep;25(9):912-8.
DOI Direct Link

View more research publications.

HAPLN1 results (if any) from reagent suppliers

Google CSE Logo
HAPLN1 (C-14) Antibody sc-46825
HAPLN1 shRNA (h) Lentiviral Particles, sc-60094-V, 200 µl ... HAPLN1 (C-14): sc- 46825. Western blot analysis of HAPLN1 expression in HeLa whole cell lysate. ...
http://www.scbt.com/datasheet-46825-hapln1-c-14-antibody.htm...

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Human HAPLN1 Affinity Purified Polyclonal Ab
specific IgG was purified by human HAPLN1 affinity chromatography. ... HAPLN1 have been identified. Whereas, the 48 kDa and 44 kDa forms differ in ...
http://www.rndsystems.com/pdf/AF2608.pdf...

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HAPLN1 (N-18) Antibody sc-46828
goat polyclonal IgG, 200µg/ml; epitope mapping at the N-terminus of HAPLN1 of human origin; recommended for detection of HAPLN1 of human and, ...
http://www.scbt.com/datasheet-46828-hapln1-n-18-antibody.htm...

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Immunohistochemistry : HAPLN4 - R&D Systems
In Western blots, this antibody shows less than 1% cross-reactivity with recombinant human HAPLN1. Secondary Antibodies R&D Systems offers a wide range
of ...
http://www.rndsystems.com/ihc_molecule_images.aspx?m=3506...

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HAPLN Antibody / HAPLN Antibodies
HAPLN1 (C-14) Antibody, sc-46825, goat IgG, C-terminus (h), WB, IP, IF, ELISA, m , r, h, horse. HAPLN1 (N-18) Antibody, sc-46828, goat IgG, N-terminus (h) ...
http://www.scbt.com/table-hapln.html...

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Cell Biology FOCUS
HAPLN1. H. H. Hyaluronate;. 6.55, 35, 132, & 1100 kDa. Layilin. H M. H M. LYVE-1 . H M. H M. TSG-6. H M. Versican. H. EXTRACELLULAR MATRIX ...
http://www.rndsystems.com/DAM_public/5816.pdf...

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HAPLN1 siRNA (m) sc-60095
Click here for details. suitable control antibody: HAPLN1 (C-14): sc-46825; sqRT -PCR Primer also available: HAPLN1 (m)-PR: sc-60095-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-60095-hapln1-sirna-m.html...

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