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CSK
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17491594 |
c-Src is recruited by AF-6 to cell-cell contact sites, suggesting that c-Src is regulated by a PDZ protein in special cellular locations. |
| 18039857 |
C terminus of c-Src via its Gly-Glu-Asn-Leu sequence presents a mechanism that restricts c-Src in epithelia and prevents progression toward an invasive phenotype |
| 17936276 |
The interaction of c-Src with LNX1 depends on the C-terminal PDZ ligand of c-Src. |
| 17692281 |
Thus, these results suggest that endogenous c-Src, c-Yes, and Lyn are differentially activated through Cdc2 activation during M phase. |
| 17936985 |
A full-length encoding cDNA of the tyrosine kinase csk gene of human lymphocytes was cloned. |
| 17691821 |
These results demonstrate that the chimeric strategy is useful for detailed dissection of the mechanistic basis of substrate specificity and regulation of protein tyrosine kinases. |
| 17525734 |
Csk is activated by increase of p140Cap which leads to inhibition of Src and downstream signalling as well as of cell motility and invasion |
| 12686554 |
functions of the activation loop in phosphorylation of its physiological substrate Src probed by extensive site-specific mutagenesis and kinetic studies |
| 16135530 |
this study reveals a mechanism by which Src family kinases may control PDGF-mediated responses both at transcriptional and translational levels. |
| 15743820 |
Csk tyrosine kinase interacts with G3BP, a new player in T-cell-antigen receptor signaling, which reduces the amount of Csk in the immune synapse. | →View more information from publications. |
Recent Publications on CSK: |  |
Interactions between the Fyn SH3-domain and adaptor protein Cbp/PAG derived ligands, effects on kinase activity and affinity.
Csk-binding protein/phosphoprotein associated with... | 28th October, 2008
| The Biotechnology Centre of Oslo, University of Oslo, Norway.
| FEBS J. 2008 Oct;275(19):4863-74. Epub 2008 Aug 21.
DOI Direct Link |
Activation of c-Src and Fyn kinases by protein tyrosine phosphatase RPTPalpha is substrate-specific and compatible with lipid raft localization.
Tyrosine kinases of the Src family (SFKs) function in multiple signaling... | 25th October, 2008
| UMR Epigenetique et destin cellulaire, UFR Sciences du Vivant, Universite
| J Biol Chem. 2008 Oct 23.
DOI Direct Link |
[Essential thrombocythemia as critical stroke risk factor--case report]
One of the haematological causes of stroke is essential thrombocythemia... | 24th October, 2008
| Wojskowy Instytut Medyczny w Warszawie, CSK MON, Klinika Neurologiczna.
| Pol Merkur Lekarski. 2008 Aug;25(146):158-60.
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[Beating myocardial cross sections and polar maps techniques in assessment of myocardial perfusion disturbances with gated single photon emission tomography]
In modern world the risk of circulatory system diseases is increasing.... | 24th October, 2008
| Wojskowy Instytut Medyczny w Warszawie, CSK MON, Zaklad Medycyny
| Pol Merkur Lekarski. 2008 Aug;25(146):110-4.
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Zinc signals are essential for lipopolysaccharide-induced signal transduction in monocytes.
Cytosolic alterations of calcium ion concentrations are an integral part... | 23rd October, 2008
| Institute of Immunology, Department of Cell Biology,
| J Immunol. 2008 Nov 1;181(9):6491-502.
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→View more research publications. |
CSK results (if any) from reagent suppliers | 
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