Thursday November 26 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

ADRA1D


Suggest Content
Advertise Here
Gene DB Home
Symbol:ADRA1D
Name(s):adrenergic, alpha-1D-, receptor
Type:protein-coding
Organism:Homo sapiens
Synonyms:ADRA1, ADRA1A, ADRA1R, ALPHA1, DAR, dJ779E11.2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17404580 ADRA1D polymorphisms are predictive markers of the response to beta-blockers
12442007 Observational study of gene-disease association. (HuGE Navigator)
17404580 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18187928 Investigate role of ADRA1D amino residues in binding of beta-adrenergic antagonists (prazosin/tamulosin).
18257748 ADRA1A expression was decreased in end stage renal disease. Functional receptor changes mediated vascular hypersensitivity to phenylephrine.
17681068 In the proximal and medial ureter, the distribution of ARs was alpha 1d > or = alpha 1a > alpha 1b; In the distal ureter, the distribution of ARs was alpha 1d > alpha 1a > alpha 1b
17660397 Stimulation of alpha(1D)-ARs by picomolar phenylephrine concentrations devoid of any contractile vascular effects, induces a proangiogenic phenotype in endothelial cells that is enhanced in a hypoxic environment.
15297446 alpha(1A)- and alpha(1D)-adrenergic receptors mediate G(1)-S cell-cycle arrest
17384146 Differential methylation of proximal GC boxes in the ADRA1D promoter disrupts Sp1 binding in a cell-specific manner resulting in repression of basal alpha1dAR expression.
14736874 cell surface expression of alpha1D-adrenergic receptors is controlled by heterodimerization with alpha1B-adrenergic receptors

View more information from publications.

Recent Publications on ADRA1D:

Pubmed Logo
Cloning, expression and immunolocalization of alpha1-adrenoceptor in different tissues from rhesus monkey and human male reproductive tract.
This study reports the genomic organization of the rhesus...
17th July, 2008
Section of Experimental Endocrinology, Department of Pharmacology, Mol Hum Reprod. 2008 Feb;14(2):85-96. Epub 2008 Jan 19.
DOI Direct Link
Polymorphisms of norepinephrine transporter and adrenergic receptor alpha1D are associated with the response to beta-blockers in dilated cardiomyopathy.
Recent clinical trials have clearly demonstrated that the administration...
12th March, 2008
Department of Clinical Evaluation of Medicines and Therapeutics, Graduate Pharmacogenomics J. 2008 Feb;8(1):78-84. Epub 2007 Apr 3.
DOI Direct Link
Haplotype block and superblock structures of the alpha1-adrenergic receptor genes reveal echoes from the chromosomal past.
A significant proportion of the human genome is contained within haplotype...
18th March, 2005
Pain and Neurosensory Mechanisms Branch, National Institute of Dental and Mol Genet Genomics. 2004 Dec;272(5):519-29. Epub 2004 Oct 16.
DOI Direct Link
Molecular analysis of adrenergic receptor genes and interleukin-4/interleukin-4 receptor genes in patients with interstitial cystitis.
PURPOSE: Interstitial cystitis is a chronic and sterile inflammatory...
18th December, 2002
Department of Urology, University of the Ryukyus, Nishihara, Okinawa, J Urol. 2002 Dec;168(6):2668-71.
DOI Direct Link

Patents:

Patents logo
US Patent No.Title
7592325 Methods and compositions for the treatment of eye disorders with increased intraocular pressure
7588767 Microorganisms for therapy
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
6673908 Tumor necrosis factor receptor 2

ADRA1D results (if any) from reagent suppliers

Google CSE Logo
A270 Anti-α1 Adrenergic Receptor antibody produced in rabbit ...
Gene Information, human ... ADRA1A(148), ADRA1B(147), ADRA1D(146). rat ... Adra1d(29413). mouse ... Adra1d(11550). shipped in, dry ice. storage temp. −20°
C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

Thumbshot
α1D-AR (R-20) Antibody sc-1475
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ADRA1D, 146, 20p13, NM_000678 ...
http://www.scbt.com/datasheet-1475-alpha1d-ar-r-20-antibody....

Thumbshot
Antibodies to Neurotransmitter Receptors
ADRA1D(146), human, IHC (p), pricing. A271, Anti-α2A Adrenergic Receptor antibody produced in rabbit, (polyclonal), affinity isolated antibody ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

Thumbshot
D9815 Doxazosin mesylate ≥97% (HPLC), powder
form, powder. color, white. Gene Information, human ... ADRA1A(148), ADRA1B(147) , ADRA1D(146). rat ... Adra1a(29412), Adra1b(24173), Adra1d(29413) ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=D981...

Thumbshot
594687 α-Sexithiophene
... PLA2G1B(5319), PLA2G2A(5320), TYMS(7298), UTS2R(2837). rat ... Adra1a(29412) , Adra1b(24173), Adra1d(29413), Ednra(24326), Ednrb(50672), Ltb4r(59264) ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=5946...

Thumbshot

Search Bioportfolio and other Life Science Sites for ADRA1D, or search for ADRA1D on BioPortfolio's antibody search engine.
This page has been viewed 114 times


Resources from the
NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.