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CTAG1B


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Symbol:CTAG1B
Name(s):cancer/testis antigen 1B
Type:protein-coding
Organism:Homo sapiens
Synonyms:CTAG, CTAG1, ESO1, LAGE-2, LAGE2B, NY-ESO-1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17640060 immunization with NY-ESO-1 peptides leads to strong tumor-reactive CD8+ T-cell responses
17488334 usefulness of NY-ESO-1 as a tool for tumor vaccine therapy in eliciting NY-ESO-1-specific helper T-cell responses, especially in Japanese cancer patients.
16140944 Data indicate that reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter mediates epigenetic regulation of this CT gene in lung cancer cells.
12209997 strong MAGE-A4 expression and to a lesser degree NY-ESO-1 expression is characteristic of the vast majority of uterine carcinosarcomas and a major subset of papillary serous carcinomas
15671442 NY-ESO-1 is frequently expressed in multiple myeloma with cytogenetic abnormality
14583496 NY-ESO-1-specific CD4(+) and CD8(+) T cells were also able to recognize NY-ESO-1 expressing neuroblastoma cells.
14522938 Data showed aberrant expression of NY-ESO-1 and LAGE-1 by IHC/RT-PCR in a significant proportion of epithelial ovarian cancer patients.
15475443 The high expression frequency of NY-ESO-1 mRNA and protein indicates NY-ESO-1 as a feasible vaccine target in esophageal cancer.
12138174 abilities of human monocyte-derived DCs and DCs derived in vitro from CD34-positive stem cells to present NY-ESO-1 epitopes to MHC class I-restricted cytotoxic T cells
11782380 NY-ESO-1 119-143 is a promiscuous major histocompatibility complex class II T-helper epitope recognized by Th1- and Th2-type tumor-reactive CD4+ T cells.

View more information from publications.

Recent Publications on CTAG1B:

Pubmed Logo
Vaccination with recombinant NY-ESO-1 protein elicits immunodominant HLA-DR52b-restricted CD4+ T cell responses with a conserved T cell receptor repertoire.
PURPOSE: ESO is a tumor-specific antigen with wide expression in human...
20th October, 2009
Institut National de la Sante et de la Recherche Medicale, CLCC Rene Clin Cancer Res. 2009 Jul 1;15(13):4467-74. Epub 2009 Jun 16.
DOI Direct Link
CT-X antigen expression in human breast cancer.
Cancer/testis (CT) genes are predominantly expressed in human germ line...
22nd September, 2009
Ludwig Institute for Cancer Research, 605 Third Avenue, New York, NY Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13493-8. Epub 2009 Jul 27.
DOI Direct Link
Spontaneous remission of a non-small cell lung cancer possibly caused by anti-NY-ESO-1 immunity.
Spontaneous remission of malignant tumors is rare and the biological...
19th September, 2009
Second Department of Internal Medicine, Nagasaki University School of Lung Cancer. 2009 Jul;65(1):119-22. Epub 2009 Feb 4.
DOI Direct Link
Cancer/testis antigens can be immunological targets in clonogenic CD133+ melanoma cells.
"Cancer stem cells" that resist conventional treatments may be a cause of...
14th August, 2009
Ludwig Institute for Cancer Research, Austin Hospital, Studley Road, Cancer Immunol Immunother. 2009 Oct;58(10):1635-46. Epub 2009 Feb 17.
DOI Direct Link
Allorestricted T lymphocytes with a high avidity T-cell receptor towards NY-ESO-1 have potent anti-tumor activity.
The cancer-testis antigen NY-ESO-1 has been targeted as a tumor-associated...
23rd July, 2009
Department of Hematology/Oncology, Klinikum Rechts der Isar, Technische Int J Cancer. 2009 Aug 1;125(3):649-55.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
A Phase I Study of NY-ESO-1 Overlapping Peptides (OLP4) Immunoadjuvants Montanide and Poly-ICLC Vaccination of Epithelial Ovarian Cancer (EOC), Fallopian Tube, or Primary Peritoneal Cancer Patients in Second or Third Remission

CTAG1B results (if any) from reagent suppliers

Google CSE Logo
CTAG1B proteins and peptides: Cancer > Tumor biomarkers > Tumor ...
CTAG1B proteins and peptides. ... Image Abreview Publication. ab83644 · CTAG1B protein (Human). SDS-PAGE, WB, Inhib, ELISA ...
http://www.abcam.com/index.html?t=124988&pt=2&c=4377&ei=&mu=...

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Antibodies to Serum Proteins
CTAG1B(1485), human, ELISA (i), IHC, WB, pricing. P9808, Monoclonal Anti- Prostatic Acid Phosphatase, Human antibody produced in mouse, PAP-29 (monoclonal
) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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NY-ESO-1 (N-12) Antibody sc-15889
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, CTAG1B, 1485, Xq28, NM_001327 ...
http://www.scbt.com/datasheet-15889-ny-eso-1-n-12-antibody.h...

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N2038 Monoclonal Anti-NY-ESO-1 antibody produced in mouse ~1 mg/mL ...
immunohistochemistry: suitable. indirect ELISA: suitable. isotype, IgG1. Gene Information, human ... CTAG1B(1485). shipped in, dry ice. storage temp. −20°C
...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...

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NY-ESO-1 (E978) Antibody sc-53869
... Numero de Accesion de Isoforma (ARNm), Numero de Accesion de la Proteina, Número de pedido: Humano, CTAG1B, 1485, Xq28, NM_001327 · P78358 ...
http://www.scbt.com/es/datasheet-53869-ny-eso-1-e978-antibod...

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Miscellaneous
human ... CTAG1B(1485), human, ELISA (i), IHC, WB, pricing. P2419, Monoclonal Anti-Peroxidase antibody produced in mouse, P6-38 (monoclonal), ascites fluid
...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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Abcam antibodies and reagents product map
... CITED1 proteins and peptides (1) · CTAG1B antibodies (1) · CTAG1B proteins and peptides (1) · CYLD antibodies (3) · CYLD proteins and peptides (2) ...
http://www.abcam.com/index.html?cl=251&pageconfig=productmap...

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