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AANAT


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Gene DB Home
Symbol:AANAT
Name(s):arylalkylamine N-acetyltransferase
Type:protein-coding
Organism:Homo sapiens
Synonyms:AA-NAT, SNAT
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11393533 Observational study of genotype prevalence. (HuGE Navigator)
12736803 Observational study of gene-disease association. (HuGE Navigator)
14728993 Observational study of gene-disease association. (HuGE Navigator)
15332344 Observational study of gene-disease association. (HuGE Navigator)
17503170 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
12736803 There is a significant increase in AANAT allele positivity at the single nucleotide polymorphism (alanine 129--> threonine) at between patients with DSPS & controls. AA-NAT could be a susceptibility gene for DSPS.
15332344 Data suggest that the -263G/C single nucleotide polymorphism of arylalkylamine-N-acetyl-transferase (AA-NAT) may be an important determinant of the late/short sleep pattern.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDAralkylamine N-acetyltransferasetyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide--Pubmed
HPRDarylalkylamine N-acetyltransferase14-3-3 zeta--Pubmed
BINDarylalkylamine N-acetyltransferasetyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptideAANAT interacts with 14-3-3-zeta isoform. This interaction was modeled on a demonstrated interaction between sheep AANAT and human 14-3-3-zeta.-Pubmed

Recent Publications on AANAT:

Pubmed Logo
Modulation of Aanat Gene Transcription in the Rat Pineal Gland.
The main function of the rat pineal gland is to transform the circadian...
29th October, 2009
Department of Physiology, Faculty of Medicine and Dentistry, University of J Neurochem. 2009 Oct 27.
DOI Direct Link
[Genetic transformation of Nicotiana tabacum L. by Agrobacterium tumefaciens carrying genes in the melatonin biosynthesis pathway and the enhancement of antioxidative capability in transgenic plants]
Arylalkylamine N-acetyltransferase (AANAT) and Hydroxyindole...
20th October, 2009
Shaanxi Provincial Key Laboratory of Biotechnology, College of Life Sheng Wu Gong Cheng Xue Bao. 2009 Jul;25(7):1014-21.
Differential resetting process of circadian gene expression in rat pineal glands after the reversal of the light/dark cycle via a 24 h light or dark period transition.
Although studies involving the circadian response to time-zone transitions...
9th October, 2009
College of Biological and Environmental Engineering, Zhejiang University Chronobiol Int. 2009 Jul;26(5):793-807.
DOI Direct Link
The modulatory effect of substance P on rat pineal norepinephrine release and melatonin secretion.
Secretion of melatonin by the mammalian pineal gland is primarily...
24th September, 2009
Neuro-Behavioral Biology Center, Institute of Science and Technology for Neurosci Lett. 2009 Sep 25;461(3):258-61. Epub 2009 Jun 21.
DOI Direct Link
Cloning and characterization of a Chlamydomonas reinhardtii cDNA arylalkylamine N-acetyltransferase and its use in the genetic engineering of melatonin content in the Micro-Tom tomato.
Melatonin is found in a wide variety of plant species. Several...
18th September, 2009
Graduate School of Life and Environmental Sciences, University of Tsukuba, J Pineal Res. 2009 May;46(4):373-82. Epub 2009 Mar 30.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7521538 Crystal structure of the ternary complex of 14-3-3/Fusicoccin/PMA and methods for designing new herbicides
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
5990094 Inhibitors of sorotonin N-acetyltransferase

View more patents.

AANAT results (if any) from reagent suppliers

Google CSE Logo
Anti-AANAT Polyclonal Antibody
Polyclonal Antibody against AANAT for use in Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

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Antibodies to Neural Enzymes
Aanat(25120), rat, WB, pricing. T9573, Anti-phospho-Tyrosine Hydroxylase (pSer40 ) antibody produced in rabbit, (polyclonal), affinity isolated antibody ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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AANAT Antibody / AANAT Antibodies
AANAT Antibody / AANAT Antibodies. ... AANAT specific siRNA, sHRNA Plasmid과 shRNA Lentiviral Particles gene silencers 도 제공합니다. ...
http://www.scbt.com/ko/table-annat.html...

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AANAT (P-20) Antibody sc-55612
AANAT (P-20) 抗体 sc-55612 AANAT (P-20) Antibody sc-55612.
http://www.scbt.com/ja/datasheet-55612-aanat-p-20-antibody.h...

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AANAT Antibody / AANAT Antibodies
AANAT Antibody / AANAT Antibodies. ... AANAT 特异siRNA, shRNA 质粒和shRNA 慢病毒 颗粒基因沉默子均有产品提供。 产品包括: ...
http://www.scbt.com/zh/table-annat.html...

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AANAT (P-20) Antibody sc-55612
AANAT (P-20) Anticuerpo sc-55612 AANAT (P-20) Antibody sc-55612.
http://www.scbt.com/es/datasheet-55612-aanat-p-20-antibody.h...

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AANAT Antibody / AANAT Antibodies
AANAT El siRNA, el plásmido del sHRNA y los silenciadores especificos del gene de las partículas de Lentiviral del shRNA están también disponibles. ...
http://www.scbt.com/es/table-annat.html...

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