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CTNND1


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Symbol:CTNND1
Name(s):catenin (cadherin-associated protein), delta 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:CAS, CTNND, KIAA0384, P120CAS, P120CTN, p120
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17719574 These data suggest that serine/threonine phosphorylation of p120 influences the dynamics of E-cadherin in junctions.
18032823 The expression of p120-catenin isoforms was associated with the genomic and transcriptional phenotype of breast cancer cells.
17576929 Cortactin and p120 are shown to directly interact with each other via the cortactin N-terminal region
17334396 membranous p120 is maintained in invasive squamous cell carcinomas in tumours suggesting that p120 may be important for the collective invasion of tumours cells in vivo
16786001 the degradation of E-cadherin in response to expression of R-cadherin is due to competition for p120(ctn)
15561585 E-cadherin-deficiency in metastatic cancer may in some cases be due to p120 downregulation [review]
11855855 The interaction of VE-cadherin with p120 catenin plays an important role in cellular growth, suggesting that the binding of p120 catenin to cadherins may regulate cell proliferation.
17344476 identification of Gli-similar 2 (Glis2) as a novel binding protein for p120 catenin
17383052 P120CTN was expressed stongly on the cuboidal cell membrane and cytoplasm of both tumor types. In polygonal cells, expression was decreased and mostly cytoplasmic.
16226102 Increased expression of delta-catenin is associated with the down-regulation and redistribution of ECAD and p120ctn in prostatic cancer.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDE-cadherincatenin, delta 1 isoform 1B--Pubmed
HPRDE-cadherincatenin, delta 1 isoform 1B--Pubmed
BINDcadherin 1, type 1 preproproteinHomo sapiens p120 catenin isoform 3AC mRNA, alternatively spliced, complete cds.CDH1(Ecad) interacts with P120ctn 3AC. This interaction was modelled on a demonstrated interaction between mouse CDH1(Ecad) and human P120ctn 3AC.-Pubmed
HPRDCadherin 3catenin, delta 1 isoform 1B--Pubmed
HPRDcadherin 3, type 1 preproproteinCatenin, delta 1--Pubmed
HPRDcadherin 5, type 2 preproproteincatenin, delta 1 isoform 1B--Pubmed
HPRDcadherin 5, type 2 preproproteincatenin, delta 1 isoform 1B--Pubmed
HPRDalpha 1 type XVII collagencatenin, delta 1 isoform 1B--Pubmed
HPRDalpha 1 type XVII collagencatenin, delta 1 isoform 1B--Pubmed
HPRDCatenin, delta 1cortactin isoform a--Pubmed

Recent Publications on CTNND1:

Pubmed Logo
ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing.
Cell-type-specific expression of epithelial and mesenchymal isoforms of...
28th March, 2009
Department of Medicine, Renal Division, University of Pennsylvania School Mol Cell. 2009 Mar 13;33(5):591-601.
DOI Direct Link
Differential gene expression in cumulus cells as a prognostic indicator of embryo viability: a microarray analysis.
Besides the established selection criteria based on embryo morphology and...
29th July, 2008
Department of Obstetrics and Gynaecology, Research Institute Growth and Mol Hum Reprod. 2008 Mar;14(3):157-68. Epub 2008 Jan 18.
DOI Direct Link
Differential gene expression patterns and interaction networks in BCR-ABL-positive and -negative adult acute lymphoblastic leukemias.
PURPOSE: To identify gene expression patterns and interaction networks...
16th May, 2007
Division of Medical Oncology, Stanford University School of Medicine, J Clin Oncol. 2007 Apr 10;25(11):1341-9. Epub 2007 Feb 20.
DOI Direct Link

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7341866 .alpha.-catenin expressed in heart and testis
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

CTNND1 results (if any) from reagent suppliers

Google CSE Logo
p-p120 (pY280.18) Antibody sc-136016
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, CTNND1, 1500, 11q12.1, O60716 ...
http://www.scbt.com/datasheet-136016-p-p120-py280-18-antibod...

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GLIS2 antibody, GLIS2 (GLIS family zinc finger 2) Antibody, Rabbit ...
Interacts with CTNND1. Subcellular Location: Nucleus speckle (By similarity). ... Ptm: C-terminus cleavage is induced by interaction with CTNND1 and ...
http://www.genwaybio.com/product_info.php?products_id=42012...

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CD-CY
HPA015955, Anti-CTNND1 antibody produced in rabbit, affinity isolated antibody, human ... CTNND1(1500), human, IHC (p), PA, WB, pricing ...
https://www.sigmaaldrich.com/etc/controller/controller-page....

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Kaiso antibody [6F / 6F8] - ChIP Grade (ab12723) | Abcam
Immunoprecipitation analysis showed that Kaiso interacts with Ctnnd1 but not with ... Yeast 2 hybrid analysis indicated that the armadillo repeats of Ctnnd1
...
http://www.abcam.com/Kaiso-antibody-6F-6F8-ChIP-Grade-ab1272...

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p120 (S-19) Antibody sc-1101
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Mouse, Ctnnd1, 12388, 2 D, P30999 ...
http://www.scbt.com/datasheet-1101-p120-s-19-antibody.html...

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E Cadherin antibody, E Cadherin [DECMA-1] Antibody, Rat Monoclonal ...
Interacts with AJAP1, CTNND1 and DLGAP5. Subcellular Location: Cell junction. Cell membrane; Single-pass type I membrane protein. ...
http://www.genwaybio.com/product_info.php?products_id=190575...

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A-Z Bethyl Laboratories
CTNND1 · CTR9 · Cul3 · Cul4a · Cul5 · Cul7 · Cyclic GMP · Cyclin C · Cyclin E1 · Cyclin H · Cyclin K · Cyclin L1 · Cyclin L2 · Cyclin T2 ...
http://www.bethyl.com/category/PCA_A-Z/Antibody/AAAAAAAABAAG...

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