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CXADR
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17031523 |
levels of CAR expression observed in cases of squamous cell carcinoma lung cancers, and in cases of small cell lung cancers, and in adenocarcinoma lung cancers |
| 18081225 |
The data indicated that the five colon cancer cell lines tested expressed CAR and could be efficiently infected by adenoviral vectors. |
| 17494992 |
Data show that human pancreatic islet endothelial cells express coxsackievirus and adenovirus receptor and are activated by coxsackie B virus infection. |
| 16951199 |
Genistein combined wwith a histone deacetylase inhibitor can inhibit cancer by altering the transcriptional regulation of CXADR. |
| 15831949 |
swine vesicular disease virus isolates from early and recent outbreaks have been compared for their capacity to utilize the progenitor virus receptors coxsackie-adenovirus receptor and decay-accelerating factor |
| 14978041 |
identified 3 CAR isoforms lacking the transmembrane domain and are the result of alternative RNA splicing events between exons IV and VII (CAR4/7), exons III and VII (CAR3/7), and exons II and VII (CAR2/7); CAR4/7 but not CAR2/7 binds to coxsackievirus B3 |
| 16923808 |
determined the crystal structures of canine adenovirus serotype 2 (CAV-2) and the human adenovirus serotype 37 (HAd37) in complex with human CAR D1 at 2.3 and 1.5A resolution, respectively |
| 12920584 |
Since DAF is abundantly expressed in epithelial and endothelial cells, interaction of cardiotropic Coxsackie Virus B with the DAF coreceptor protein, in addition to CAR, could therefore be advantageous to the virus by enhancing viral entry into the heart. |
| 15364909 |
Results indicate that the coxsackievirus and adenovirus receptor interacts with multi-PDZ domain protein 1 (MUPP1) and is involved in MUPP1 recruitment to the tight junction. |
| 15456946 |
Data suggest that modulating the expression of integrin subunits beta3/5 in human neurons may enhance adenoviral infectivity via the coxsackie-adenovirus receptor. | →View more information from publications. |
Recent Publications on CXADR: |  |
Combination of soluble coxsackievirus-adenovirus receptor and anti-coxsackievirus siRNAs exerts synergistic antiviral activity against coxsackievirus B3.
Coxsackievirus B3 (CVB-3) is a major causative agent of chronic heart... | 10th October, 2009
| Free University Berlin, Institute for Chemistry and Biochemistry,
| Antiviral Res. 2009 Sep;83(3):298-306. Epub 2009 Jul 8.
DOI Direct Link |
Adenovirus serotype 5 infects human dendritic cells via a coxsackievirus-adenovirus receptor-independent receptor pathway mediated by lactoferrin and DC-SIGN.
The coxsackievirus-adenovirus receptor (CAR) is the described primary... | 31st July, 2009
| Center for Infectious Medicine, Department of Medicine, Karolinska
| J Gen Virol. 2009 Jul;90(Pt 7):1600-10. Epub 2009 Mar 12.
DOI Direct Link |
Role of genetic susceptibility to latent adenoviral infection and decreased lung function.
BACKGROUND: Latent adenoviral infection may amplify cigarette... | 9th June, 2009
| The James Hogg iCAPTURE Centre, University of British Columbia, St Paul's
| Respir Med. 2009 Nov;103(11):1672-80. Epub 2009 Jun 6.
DOI Direct Link |
Specificity switching in virus-receptor complexes.
Several structures of complexes between viral attachment proteins and... | 9th June, 2009
| Interfaculty Institute for Biochemistry, University of Tuebingen,
| Curr Opin Struct Biol. 2009 Apr;19(2):181-8. Epub 2009 Apr 1.
DOI Direct Link |
Construction of urothelium-specific recombinant adenovirus and its inhibition in bladder cancer cell.
AIM: To construct urothelium-specific recombinant adenovirus and... | 1st May, 2009
| Institute of Urology, Second Hospital of Lanzhou University, Lanzhou, PR
| Urol Int. 2009;82(2):209-13. Epub 2009 Mar 19.
DOI Direct Link |
→View more research publications. |
CXADR results (if any) from reagent suppliers | 
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Mouse CXADR Affinity Purified Polyclonal Ab
Mouse CXADR specific IgG was purified by mouse CXADR affinity chromatography. ... extracellular domain of mouse CXADR shares 97% and 90% aa sequence ...
http://www.rndsystems.com/pdf/AF2654.pdf...
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Abgent - Stem Cell
AP2793aNEW, CRMP1 Antibody (N-term), IHC, E, H. AP2852cNEW, CXADR Antibody ( Center), WB, E, H. AP2852aNEW, CXADR Antibody (N-term), WB, E, H ...
http://www.abgent.com/products/category/stem_cell...
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CXADR - R&D Systems
CXADR (coxsackie and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein of the CTX family of the Ig superfamily. ...
http://www.rndsystems.com/molecule_detail.aspx?m=2732...
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CAR (H-300) Antibody sc-15405
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, CXADR, 1525, 21q21.1, NM_001338 ...
http://www.scbt.com/datasheet-15405-car-h-300-antibody.html...
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Monoclonal Anti-human AMICA-Allophycocyanin
AMICA with coxsackie virus and adenovirus receptor (CXADR) in epithelial tight ... homophilically, as neutrophils adhere to immobilized CXADR but not to ...
http://www.rndsystems.com/pdf/FAB34491A.pdf...
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JAML antibody (ab67843) | Abcam
JAML (junctional adhesion molecule-like) mediates adhesive interactions with CXADR, a protein of the junctional complex of epithelial cells, via the Ig-like
...
http://www.abcam.com/JAML-antibody-ab67843.html...
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Recombinant
A DNA sequence encoding the extracellular domain of human CXADR (Leu 20 - Gly ... The recombinant human CXADR/Fc is a disulfide-linked homodimeric protein.
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http://www.rndsystems.com/pdf/3336-CX.pdf...
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