Thursday November 26 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

ADRB1


Suggest Content
Advertise Here
Gene DB Home
Symbol:ADRB1
Name(s):adrenergic, beta-1-, receptor
Type:protein-coding
Organism:Homo sapiens
Synonyms:ADRB1R, B1AR, BETA1AR, RHR
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18155231 Endoplasmic reticulum stress plays an important role in cell death and cardiac dysfunction in beta(1)-extracellular loop (EC)(II) IgG cardiomyopathy, and the effects of beta(1)-EC(II) IgG are mediated via the beta(1)-adrenergic receptor.
18209576 the beta1AR gene is highly polymorphic and is commonly found in six haplotypic forms in the population; receptor expression varies by haplotype
18209576 Observational study of genotype prevalence. (HuGE Navigator)
18219297 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18239290 Observational study of gene-disease association. (HuGE Navigator)
18253135 Observational study of gene-disease association. (HuGE Navigator)
18298953 Observational study of gene-disease association. (HuGE Navigator)
18308161 Observational study of gene-disease association. (HuGE Navigator)
18331634 Observational study of gene-disease association. (HuGE Navigator)
18346809 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDalpha-2A-adrenergic receptorbeta-1-adrenergic receptorAlpha-2A-AR interacts with beta-1-AR.-Pubmed
BINDbeta-1-adrenergic receptorG protein-coupled receptor associated sorting protein 2GASP-2 interacts with beta-1-AR.-Pubmed
HPRDbeta-1-adrenergic receptorpostsynaptic density protein 95--Pubmed
HPRDbeta-1-adrenergic receptorpostsynaptic density protein 95--Pubmed
BINDbeta-1-adrenergic receptorgrowth factor receptor-bound protein 2 isoform 1beta-1-AR interacts with Grb2.-Pubmed
BINDbeta-1-adrenergic receptorSH3-domain GRB2-like 2Beta-1-AR interacts with SH3p4. This interaction was modeled on a demonstrated interaction between human Beta-1-AR and rat or cow SH3p4.-Pubmed
BINDbeta-1-adrenergic receptorSH3-domain GRB2-like 3Beta-1-AR interacts with SH3p13. This interaction was modeled on a demonstrated interaction between human Beta-1-AR and rat SH3p13.-Pubmed
HPRDbeta-1-adrenergic receptorarrestin beta 1 isoform A--Pubmed
HPRDbeta-1-adrenergic receptorarrestin beta 1 isoform A--Pubmed
BINDbeta-1-adrenergic receptorregulator of G-protein signalling 19 interacting protein 1 isoform 1The carboxy terminus of beta-1-AR interacts with GIPC.-Pubmed

Recent Publications on ADRB1:

Pubmed Logo
GRK5 Gln41Leu polymorphism is not associated with sensitivity to beta(1)-adrenergic blockade in humans.
AIMS: A common, functionally significant polymorphism in GRK5 (Gln41Leu)...
22nd October, 2009
Vanderbilt University, Nashville, TN, USA. Pharmacogenomics. 2009 Oct;10(10):1581-7.
DOI Direct Link
Association of beta-1 and beta-2 adrenergic receptor gene polymorphisms with myocardial infarction.
Both beta(1)- and beta2-adrenergic receptors (beta(1)- and beta(2)-AR)...
7th October, 2009
Department of Medical Biology and Genetics, Faculty of Medicine, Gazi J Clin Lab Anal. 2009;23(4):237-43.
DOI Direct Link
Genetic Factors Are Relevant and Independent Determinants of Antihypertensive Drug Effects in a Multiracial Population.
BackgroundThe success of antihypertensive drugs may be improved by better...
26th September, 2009
Department of Clinical Pharmacy, Academic Medical Center, Amsterdam, the Am J Hypertens. 2009 Sep 24.
DOI Direct Link
Clinical and genetic modifiers of long-term survival in heart failure.
OBJECTIVES: This study sought to identify genetic modifiers of...
17th September, 2009
Center for Pharmacogenomics, Department of Medicine, Washington University J Am Coll Cardiol. 2009 Jul 28;54(5):432-44.
DOI Direct Link
Adrenergic beta-1 receptor genetic variation predicts longitudinal rate of GFR decline in hypertensive nephrosclerosis.
BACKGROUND: End-stage renal disease (ESRD) due to hypertension is common...
12th September, 2009
1Department of Medicine, University of California, San Diego, and San Nephrol Dial Transplant. 2009 Sep 10.
DOI Direct Link

View more research publications.

BioNews Results for ADRB1

: RSS Logo
BioPortfolio Logo
Trp64Arg polymorphism in ADRB3 gene is associated with elite endurance performance
British Journal of Sports Medicine:  Oct 15 2009 12:44AM Matching: adrb1

Patents:

Patents logo
US Patent No.Title
7592325 Methods and compositions for the treatment of eye disorders with increased intraocular pressure
5581628 Characters reading apparatus having collating means of envelope
6673908 Tumor necrosis factor receptor 2
6780609 High bone mass gene of 1.1q13.3
6994848 Lactobacillus paracasei strain GM-080 for treating allergy related diseases

View more patents.

ADRB1 results (if any) from reagent suppliers

Google CSE Logo
Cancer Antibodies :: Page 3
ADRA2A Antibody, 45-210, H, M, R, D, E, ICC, IF, ADRA2A. ADRB1 Antibody, 45-211, H, M, R, D, E, WB, ADRB1. ADRB2 Antibody, 45-212, H, E, WB, ADRB2R / ADRB2 ...
http://www.prosci-inc.com/shop/catalog1/Cancer-Antibodies-p-...

Thumbshot
Cell Type, Tissue, Tumor, and Organ-Specific Markers - GeneTex Inc ...
ADRB1 antibody (adrenergic, beta-1-, receptor), GTX108366, Rabbit PAb, WB, 100 μl, USD $269.00, -. ADRB3 antibody (adrenergic, beta-3-, receptor), GTX108200
...
http://www.genetex.com/WebPage/Product/Catalog.aspx?Type=Sea...

Thumbshot
Antibodies to Neurotransmitter Receptors
A272, Anti-β1 Adrenergic Receptor antibody produced in rabbit, (polyclonal), affinity isolated antibody, mouse ... Adrb1(11554) rat ... Adrb1(24925) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

Thumbshot
BDKRB1 antibody, B1 bradykinin receptor Antibody, Rabbit ...
ADRB1, IgG · B1 bradykinin receptor, IgG · SUGGESTED ANITBODY REAGENTS - GenWay has an extensive selection of reagents useful for antibody applications. ...
http://www.genwaybio.com/product_info.php?products_id=10180...

Thumbshot
β1-AR (A-20) Antibody sc-567
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ADRB1, 153, 10q25.3, NM_000684 ...
http://www.scbt.com/datasheet-567-beta1-ar-a-20-antibody.htm...

Thumbshot
beta 1 Adrenergic Receptor antibody (ab64996) | Abcam
ADRB1 is an beta-adrenergic receptor. Beta receptors are coupled to Gs proteins, which in turn are linked to adenylyl cyclase. Agonist binding thus c...
http://www.abcam.com/beta-1-Adrenergic-Receptor-antibody-ab6...

Thumbshot
Peptides :: Page 5
ADRA2A Peptide, 45-210P, n/a, Bl, ADRA2A peptide. ADRB1 Peptide, 45-211P, n/a, Bl, ADRB1 peptide. ADRB2 Peptide, 45-212P, n/a, Bl, ADRB2 peptide ...
http://www.prosci-inc.com/shop/catalog1/Peptides-p-5-c-142.h...

Thumbshot

Search Bioportfolio and other Life Science Sites for ADRB1, or search for ADRB1 on BioPortfolio's antibody search engine.
This page has been viewed 257 times
Recent Search Terms used to find this page:
ADRB-1 GENE POLYMORPHISM | ADRB1 | sites where B1 ADRENERGIC RECEPTORS FOUND | beta 1 receptor | beta 1 receptor gene | beta 1 receptor | beta 1 receptor | ADRB1 | beta 1 receptors | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.