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DAB2IP


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Symbol:DAB2IP
Name(s):DAB2 interacting protein
Type:protein-coding
Organism:Homo sapiens
Synonyms:AF9Q34, AIP1, DIP1/2, FLJ39072, KIAA1743
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18073375 Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)
18073375 Analysis of SNPs indicated that one, rs1571801, located in the DAB2IP gene, which encodes a novel Ras GTPase-activating protein and putative prostate tumor suppressor, was associated with aggressive prostate cancer.
16328005 promoter methylation of the hDAB2IP gene is involved in the progression of urinary bladder transitional cell carcinoma from a low to a high malignant potential
15310755 AIP1 is a novel transducer in TNF-induced TRAF2-dependent activation of ASK1 that mediates a balance between JNK versus NF-kappaB signaling
12446720 Epigenetic regulation of this novel tumor suppressor gene in prostate cancer cell lines.
15386433 Our results demonstrate that hDAB2IP methylation is frequently present in lung cancers and plays a key role in hDAB2IP silencing.
15041729 hDAB2IP methylation frequently is present in breast cancer and plays a key role in hDAB2IP inactivation.
15817459 hDAB2IP gene is a target gene of Ezh2 in prostatic epithelium, which provides an underlying mechanism of the down-regulation of hDAB2IP gene in prostate cancer
11944990 Normal prostatic epithelial cells have elevated DAB2IP mRNA compared with cancer cells, which correlates with increased DAB2IP promoter activity.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDDAB1DAB2 interacting protein isoform 1--Pubmed
HPRDDisabled-1DAB2 interacting protein isoform 1--Pubmed
HPRDdisabled homolog 1DAB2IP--Pubmed
HPRDmitogen-activated protein kinase kinase kinase 5DAB2 interacting protein isoform 1--Pubmed

Patents:

Patents logo
US Patent No.Title
7612181 Dual variable domain immunoglobulin and uses thereof
7504225 Reagents and methods for use in cancer diagnosis, classification and therapy

DAB2IP results (if any) from reagent suppliers

Google CSE Logo
Dab1 antibody, Dab1 phospho Y198 Antibody, Rabbit Polyclonal Antibody
Interacts with DAB2IP and SIAH1 (By similarity). Interacts with LRP1. Domain: The PID domain specifically binds to the Asn-Pro-Xaa-Tyr(P) motif found in ...
http://www.genwaybio.com/product_info.php?products_id=197449...

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AIP Antibody / AIP Antibodies
제품명, 카탈로그 번호, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. AIP1 (H-188) Antibody, sc-98670, rabbit IgG, 641-828 (h), WB, IP, IF, ELISA, m, r, h, ...
http://www.scbt.com/ko/table-aip.html...

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AIP1 (H-188) Antibody sc-98670
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, DAB2IP, 153090, 9q33.2, Q5VWQ8 ...
http://www.scbt.com/ko/datasheet-98670-aip1-h-188-antibody.h...

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AIP1 (H-188) Antibody sc-98670
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, DAB2IP, 153090, 9q33.2, Q5VWQ8 ...
http://www.scbt.com/ja/datasheet-98670-aip1-h-188-antibody.h...

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AIP Antibody / AIP Antibodies
製品名, カタログ番号, アイソタイプ, エピトープ, アプリケーション, 動物種. AIP1 ( H-188) 抗体, sc-98670, rabbit IgG, 641-828 (h), WB, IP, IF, ELISA, m, r, h, ...
http://www.scbt.com/ja/table-aip.html...

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AIP1 (H-188) Antibody sc-98670
... Numéro d'accès de la protéine, Numéro OMIM™. Humain, DAB2IP, 153090, 9q33.2, Q5VWQ8 · 609205. Souris, Dab2ip, 69601, 2 B, Q3UHC7, Non disponible ...
http://www.scbt.com/fr/datasheet-98670-aip1-h-188-antibody.h...

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