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CYP1A1


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Symbol:CYP1A1
Name(s):cytochrome P450, family 1, subfamily A, polypeptide 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18200441 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18203021 Observational study of gene-disease association. (HuGE Navigator)
18203634 Observational study of gene-disease association. (HuGE Navigator)
18224491 Observational study of gene-disease association. (HuGE Navigator)
18241825 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18247309 Observational study of gene-disease association. (HuGE Navigator)
18261353 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18268125 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18285692 Observational study of gene-disease association. (HuGE Navigator)
18287863 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCytochrome b-5cytochrome P450, family 1, subfamily A, polypeptide 1--Pubmed
HPRDcytochrome b-5 isoform 1Cytochrome p450 subfamily, polypeptide 1--Pubmed

Recent Publications on CYP1A1:

Pubmed Logo
Suppression of AhR signaling pathway is associated with the downregulation of UDP-glucuronosyltransferases during BBN-induced urinary bladder carcinogenesis in mice.
Downregulation of carcinogen detoxifying enzymes might be a critical...
3rd November, 2009
Department of Urology, Institute of Clinical Medicine, Center for TARA and J Biochem. 2009 Oct 29.
DOI Direct Link
Importance of CYP1A1 and CYP1B1 in bioactivation of benzo[a]pyrene in human lung cell lines.
Polycyclic aromatic hydrocarbons are ubiquitous environmental pollutants...
3rd November, 2009
Section for Toxicology, Department of Chemical and Biological Working Toxicol Lett. 2009 Oct 29.
DOI Direct Link
Differential effects of nitro-PAHs and amino-PAHs on cytokine and chemokine responses in human bronchial epithelial BEAS-2B cells.
Nitro-polycyclic aromatic hydrocarbons (nitro-PAHs) are found in diesel...
3rd November, 2009
Department of Air Pollution and Noise, Division of Environmental Medicine, Toxicol Appl Pharmacol. 2009 Oct 28.
DOI Direct Link
SNP genotyping of unpurified PCR products by sandwich-type affinity electrophoresis on a microchip with programmed autonomous solution filling.
We demonstrate rapid single-nucleotide polymorphism (SNP) genotyping on a...
30th October, 2009
Bioengineering Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Lab Chip. 2009 Nov 21;9(22):3297-302. Epub 2009 Aug 28.
DOI Direct Link
Possible Risk Modification by Polymorphisms of Estrogen Metabolizing Genes in Familial Breast Cancer Susceptibility in an Indian Population.
ABSTRACT This case control study investigated whether polymorphisms of...
30th October, 2009
Regional Cancer Centre, Division of Cancer Research, Medical College Post, Cancer Invest. 2009 Oct 28.

View more research publications.

Press Releases on CYP1A1:

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Tigris Pharmaceuticals Presents Results of Breast Cancer Research at AACR Annual Meeting 30th April, 2009 Tigris Pharmaceuticals, Inc.

BONITA SPRINGS, Fla., April 30 /PRNewswire/ -- Tigris Pharmaceuticals, Inc., a privately held drug development company, announced that preclinical data were presented on its novel molecule, AFP-464

BioNews Results for CYP1A1

: RSS Logo
BioPortfolio Logo
3-Methylcholanthrene and benzo(a)pyrene modulate cardiac cytochrome P450 gene expression and arachidonic acid metabolism in male Sprague Dawley rats
Laboratory Investigation:  Nov 5 2009 5:19AM Matching: cyp1a1
Pomegranates vs Prostate Cancer
American Chemical Society:  Nov 2 2009 1:04PM Matching: cyp1a1
Life Sciences: Researchers from Tokyo University, Faculty of Pharmaceutical Sciences discuss findings in life sciences
NewsRX:  Oct 31 2009 4:59AM Matching: cyp1a1
Comparative Analysis of AhR-Mediated TCDD-Elicited Gene Expression in Human Liver Adult Stem Cells
Toxicological Sciences:  Oct 27 2009 10:50PM Matching: cyp1a1

Clinical Trials:

Clinical Trials Logo
Molecular Epidemiology of Dioxin-Related Illness in Seveso

Patents:

Patents logo
US Patent No.Title
7442765 Secreted transmembrane polypeptides and nucleic acids encoding the same
7479545 PRO6001 antibodies
7482334 Therapeutic treatment methods
7488586 PRO4409 polypeptides
7488796 PRO1269 polypeptides

View more patents.

CYP1A1 results (if any) from reagent suppliers

Google CSE Logo
CYP1A1 (G-18) Antibody sc-9828
Dexamethasone controls aryl hydrocarbon receptor (AhR)-mediated CYP1A1 and CYP1A2 expression and activity in primary cultures of human hepatocytes. ...
http://www.scbt.com/datasheet-9828-cyp1a1-g-18-antibody.html...

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CYP1A1 Antibody (C-term)
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP1A1 antibody (C-term), which was peroxidase-conjugated to the secondary ...
http://www.abgent.com/products/catalog_no/AP7993b_CYP1A1_Ant...

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CYP1A1 (H-70) Antibody sc-20772
See how others have used CYP1A1 (H-70): sc-20772 antibody and or CYP1A1 (H-70) ... Preferential induction of CYP1A1 and CYP1B1 in CCSP-positive cells. ...
http://www.scbt.com/datasheet-20772-cyp1a1-h-70-antibody.htm...

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CYP1A1 Antibody (C-term)
Western blot analysis of anti-CYP1A1 Antibody (Center) (Cat.#AP7993c) in mouse lung tissue lysates (35ug/lane). CYP1A1 (arrow) was detected using the ...
http://www.abgent.com/products/catalog_no/AP7993c_CYP1A1_Ant...

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CYP1A1 (B-4) Antibody sc-25304
Western blot analysis of human recombinant CYP1A1 fusion protein (A) and CYP1A1 ... CYP1A1 (B-4): sc-25304. Western blot analysis of CYP1A1 expression in ...
http://www.scbt.com/datasheet-25304-cyp1a1-b-4-antibody.html...

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CYP1A1 Induction Assay
The GeneBLAzer® CYP1A1-bla LS-180 cell line allows measurement of CYP1A1 induction via a beta-lactamase reporter gene (Figure 1). The beta-lactamase (bla
) ...
http://www.invitrogen.com/site/us/en/home/Products-and-Servi...

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CYP1A1 (B-2) Antibody sc-48432
CYP1A1 shRNA (h) Lentiviral Particles, sc-41483-V, 200 µl ... Western blot analysis of human recombinant CYP1A1 fusion protein. Download ...
http://www.scbt.com/datasheet-48432-cyp1a1-b-2-antibody.html...

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