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CYP1A1


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Symbol:CYP1A1
Name(s):cytochrome P450, family 1, subfamily A, polypeptide 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
Links: Pubmed, Entrez Gene, GeneCards, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18200441 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18203021 Observational study of gene-disease association. (HuGE Navigator)
18203634 Observational study of gene-disease association. (HuGE Navigator)
18224491 Observational study of gene-disease association. (HuGE Navigator)
18241825 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18247309 Observational study of gene-disease association. (HuGE Navigator)
18261353 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18268125 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18285692 Observational study of gene-disease association. (HuGE Navigator)
18287863 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCytochrome b-5cytochrome P450, family 1, subfamily A, polypeptide 1--Pubmed
HPRDcytochrome b-5 isoform 1Cytochrome p450 subfamily, polypeptide 1--Pubmed

Recent Publications on CYP1A1:

Pubmed Logo
Effects of Leuzea carthamoides on Human Breast Adenocarcinoma MCF-7 Cells Determined by Gene Expression Profiling and Functional Assays.
Products derived from roots of LEUZEA CARTHAMOIDES (Maral root) are being...
1st November, 2008
Institute of Pharmacy, University of Jena, Jena, Germany. Planta Med. 2008 Oct 29.
DOI Direct Link
Organic Chemicals Adsorbed onto Diesel Exhaust Particles Directly Alter the Differentiation of Fetal Thymocytes Through Arylhydrocarbon Receptor but Not Oxidative Stress Responses.
Diesel exhaust particles (DEP) were reported to have adverse effects on...
30th October, 2008
Environmental Health Sciences Division, National Institute for J Immunotoxicol. 2006 Jan 1;3(1):21-30.
DOI Direct Link
The Effects of Indirubin-3'-Monoxime, A Novel AHR Ligand, on Stress and Toxicity-Related Gene/Protein Expression in Human U937 Cells Undergoing Differentiation and Activation.
Indirubin-3-monoxime is an aryl hydrocarbon receptor (AhR)-binding,...
30th October, 2008
Department of Biological Sciences, Clemson Institute of Environmental J Immunotoxicol. 2006 Jan 1;3(1):1-10.
DOI Direct Link
Effects of prior oral contraceptive use and soy isoflavonoids on estrogen-metabolizing cytochrome P450 enzymes.
Estrogen exposure and metabolism may play an important role in the...
29th October, 2008
Department of Pathology, Section on Comparative Medicine, Wake Forest J Steroid Biochem Mol Biol. 2008 Oct 8.
DOI Direct Link
A low halogenated biphenyl (PCB3) increases CYP1A1 expression and activity via the estrogen receptor beta in the porcine ovary.
Polychlorinated biphenyls (PCBs) have been detected at high levels, up to...
28th October, 2008
Department of Physiology and Toxicology of Reproduction, Institute of J Physiol Pharmacol. 2008 Sep;59(3):577-88.

View more research publications.

BioNews Results for CYP1A1

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Effects Of Perinatal Pbde Exposure On Hepatic Phase I, Phase Ii, Phase Iii And Deiodinase 1 Gene Expression In
Toxicological Sciences:  Nov 1 2008 6:48AM Matching: cyp1a1
Coffee intake, variants in genes involved in caffeine metabolism, and the risk of epithelial ovarian cancer
MDLinx:  Oct 29 2008 10:57AM Matching: cyp1a1
In vitro metabolism of pyrethroid pesticides by rat and human hepatic microsomes and cytochrome P450 isoforms
Drug Metabolism And Disposition:  Oct 24 2008 1:29AM Matching: cyp1a1
Roles of Coactivator Proteins in Dioxin Induction of CYP1A1 and CYP1B1 in Human Breast Cancer Cells
Toxicological Sciences:  Oct 9 2008 6:12AM Matching: cyp1a1

Clinical Trials:

Clinical Trials Logo
Molecular Epidemiology of Dioxin-Related Illness in Seveso
Toxic Exposure

Patents:

Patents logo
US Patent No.Title
7390886 PRO9822 antibodies
7405074 Glyphosate-N-acetyltransferase (GAT) genes
7405268 Secreted and transmembrane polypeptides and nucleic acids encoding the same
7405269 Secreted and transmembrane polypeptides and nucleic acids encoding the same
7407805 Skin substitutes with improved barrier function

View more patents.

CYP1A1 results (if any) from reagent suppliers

Google CSE Logo
CYP1A1 (G-18) Antibody sc-9828
See how others have used CYP1A1 (G-18): sc-9828 and or CYP1A1 (G-18) ... Western blot analysis of CYP1A1 expression in non-transfected: sc-117752 (A) and ...
http://www.scbt.com/datasheet-9828-cyp1a1-g-18-antibody.html...

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CYP1A1 Induction Assay
The GeneBLAzer® CYP1A1-bla LS-180 cell line allows measurement of CYP1A1 induction via a ... Dose response of CYP1A1 inducers in the CYP1A1-bla LS180
assay. ...
http://www.invitrogen.com/site/us/en/home/Products-and-Servi...

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CYP1A1 (1A3-03) Antibody sc-101828
Western blot analysis of CYP1A1 expression in non-transfected: sc-117752 (A) and human CYP1A1 transfected: sc-114027 (B) 293T whole cell lysates. Download ...
http://www.scbt.com/datasheet-101828-cyp1a1-1a3-03-antibody....

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GTX74412-Cytochrome P450 1A1 Antibody-GeneTex Inc.
Recognizes human cytochrome p450 1A1 (CYP1A1). P450 enzymes are divided into two ... I a neutralizing antibody which is a potent inhibitor of CYP1A1 and ...
http://www.genetex.com/ccp20485-cytochrome-p450-1a1-antibody...

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BIOMOL International, LP - Anti-CYP1A1 (human), Rabbit Polyclonal
Cytochrome P-450 1A1 (CYP1A1) is induced by polycyclic aromatic compounds such as benzpyrene, 3-methylcholanthrene (Cat. # GR-239) and TCDD. ...
http://www.biomol.com/?pageId=38&categoryId=547&productId=25...

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CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A1; AHH; AHRR; CP11; CYP1; P1-450; P450-C; P450DX. Other Designations. aryl hydrocarbon hydroxylase; cytochrome P1-450, dioxin-inducible; ...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...

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BIOMOL International, LP - Anti-CYP1A1 (rat), Rabbit Polyclonal
Such compounds have been reported to induce Cytochrome P-450 (CYP1A1) in rat liver, human placenta and lung. A rare polymorphism of the CYP1A1 gene has been
...
http://www.biomol.com/?pageId=38&categoryId=547&productId=25...

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Peptide-Human CYP1B1 control/blocking peptide-Alpha Diagnostic ...
66: 9090 - 9098 MicroRNA Regulates the Expression of Human Cytochrome P450 1B1, IHC, human MCF7, HEK cells expressing Cyp1a1 an dcyp1b1 genes ...
https://www.4adi.com/ccpc2537-10974-human-cyp1b1-control-blo...

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Polyclonal Antibody Data Sheet
Reacts with Cytochrome P450 Enzyme CYP1A1 in human placental microsomal. fraction and to recombinant human CYP1A1. Cross Reactivity: ...
http://www.fitzgerald-fii.com/uploadDocs/dataSheets/2112.pdf...

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