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ADRB3


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Gene DB Home
Symbol:ADRB3
Name(s):adrenergic, beta-3-, receptor
Type:protein-coding
Organism:Homo sapiens
Synonyms:BETA3AR
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17225053 Trp64Arg polymorphism of the beta-3 adrenergic receptor may be independently associated with hyperuricemia in males.
18273796 There was no significant difference in the genotype frequency of the beta3-AR p.W64R and the LEP c.-2548G>A polymorphisms, between lean and obese subjects.
18239290 Observational study of gene-disease association. (HuGE Navigator)
18249022 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
18249219 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18273796 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18331634 Observational study of gene-disease association. (HuGE Navigator)
18335327 Observational study of gene-disease association. (HuGE Navigator)
18088254 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
10805511 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDBeta-3-adrenergic receptorproto-oncogene tyrosine-protein kinase SRC--Pubmed
HPRDadrenergic, beta-3-, receptorc-Src--Pubmed
HPRDadrenergic, beta-3-, receptorguanine nucleotide binding protein, alpha stimulating activity polypeptide 1 isoform c--Pubmed
HPRDadrenergic, beta-3-, receptorguanine nucleotide binding protein, alpha stimulating activity polypeptide 1 isoform c--Pubmed

Recent Publications on ADRB3:

Pubmed Logo
A Preliminary Candidate Genotype-Intermediate Phenotype Study of Satiation and Gastric Motor Function in Obesity.
Stomach motility contributes significantly to fullness sensation while...
31st October, 2009
Clinical Enteric Neuroscience Translational and Epidemiological Research Obesity (Silver Spring). 2009 Oct 29.
DOI Direct Link
Extensive diversity of the ADRB3 gene in Chinese sheep identified by PCR-SSCP.
The beta(3)-adrenergic receptor (ADRB3) is the main mediator of the...
10th October, 2009
Faculty of Animal Science and Technology, Gansu Agricultural University, Biochem Genet. 2009 Aug;47(7-8):498-502. Epub 2009 Jun 9.
DOI Direct Link
Extended tracts of homozygosity identify novel candidate genes associated with late-onset Alzheimer's disease.
Large tracts of extended homozygosity are more prevalent in outbred...
17th September, 2009
Molecular Genetics Section and Laboratory of Neurogenetics, National Neurogenetics. 2009 Jul;10(3):183-90. Epub 2009 Mar 7.
DOI Direct Link
Implication of beta3-adrenoceptors in the antidepressant-like effects of amibegron using Adrb3 knockout mice in the chronic mild stress.
The involvement of the beta3-adrenoceptor in the antidepressant-like...
12th September, 2009
Sanofi-aventis, CNS Research, 31 avenue Paul Vaillant-Couturier, 92220 Behav Brain Res. 2010 Jan 20;206(2):310-2. Epub 2009 Sep 8.
DOI Direct Link
Effects of UCP2 -866 G/A and ADRB3 Trp64Arg on rosiglitazone response in Chinese patients with Type 2 diabetes.
AIMS: The aim of this study was to explore the impact of UCP2 and ADRB3...
8th August, 2009
Institute of Clinical Pharmacology, Hunan Key Laboratory of Br J Clin Pharmacol. 2009 Jul;68(1):14-22.
DOI Direct Link

View more research publications.

BioNews Results for ADRB3

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Trp64Arg polymorphism in ADRB3 gene is associated with elite endurance performance
British Journal of Sports Medicine:  Oct 15 2009 12:44AM Matching: adrb3

Clinical Trials:

Clinical Trials Logo
A Study To Investigate GW427353 In Subjects With Irritable Bowel Syndrome (IBS)

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
6525185 Polymorphisms associated with hypertension
6673908 Tumor necrosis factor receptor 2
6727063 Single nucleotide polymorphisms in genes
6770461 High bone mass gene of 11q13.3

View more patents.

ADRB3 results (if any) from reagent suppliers

Google CSE Logo
ADRB3 Antibody ADRB3
ADRB3 antibody was raised against a synthetic peptide of ADRB3.,
http://www.prosci-inc.com/shop/catalog1/ADRB3-Antibody-p-275...

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Cell Type, Tissue, Tumor, and Organ-Specific Markers - GeneTex Inc ...
ADRB3 antibody (adrenergic, beta-3-, receptor), GTX108200, Rabbit PAb, WB, 100 μl, USD $269.00, -. ADRBK1 antibody (adrenergic, beta, receptor kinase 1) ...
http://www.genetex.com/WebPage/Product/Catalog.aspx?Type=Sea...

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ADRB3 Antibody Adrenergic b3 Receptor
ADRB3 antibody reacts specifically with ADRB3 protein (about 44 kDa) of mouse and rat and may cross-rat with ADRB3 protein of other mammalian species. ...
http://www.prosci-inc.com/shop/catalog1/ADRB3-Antibody-p-101...

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Antibodies to Neurotransmitter Receptors
Adrb3(11556), human, IHC (p), pricing. A4352, Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer831) antibody produced in rabbit, (polyclonal) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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Obesity Antibodies :: Page 1
ADRB3 Antibody, 54-197, M, R, WB, Adrenergic b3 Receptor. AEBP1 Antibody, XAV- 8498, H, WB, IHC, Anti-Adipocyte Enhancer Binding Protein 1 (AEBP1) ...
http://www.prosci-inc.com/shop/catalog1/Obesity-Antibodies-p...

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β3-AR (M-20) Antibody sc-1473
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Adrb3, 11556, 8 A2, P25962 ...
http://www.scbt.com/datasheet-1473-beta3-ar-m-20-antibody.ht...

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Signal Transduction Antibodies :: Page 2
ADRA1B Antibody, 48-310, H, IHC, Alpha 1b-Adrenoceptor. ADRB3 Antibody, 46-623, H, E, WB, ADRB3. ADRB3 Antibody, 54-197, M, R, WB, Adrenergic b3 Receptor ...
http://www.prosci-inc.com/shop/catalog1/Signal-Transduction-...

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