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DAB1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17974915 |
Cul5 plays an essential role in regulating neuron migrations during cortical development, possibly by opposing a promigratory effect of Dab1. |
| 17062576 |
results suggest that the mouse ortholog is a nucleocytoplasmic shuttling protein |
| 15175076 |
significantly lower levels of disabled homolog 1 gene transcripts were detected in gangliogliomas compared to controls |
| 15718228 |
Dab1 regulates both cell surface expression and internalization of Reelin receptors |
| 14961563 |
Dab1 immunoreactivity is found in certain populations of amacrine cells of the retina, with lobular appendages in the outer half of the inner plexiform layer (IPL) and a bushy, smooth dendritic tree in the inner half of the IPL. |
| 12834112 |
RELN and DAB1 coexpression in these neurons is necessary for both normal cortical development and mature function. |
| 12581169 |
involvement of disabled homolog 1 in neurogenesis |
| 17548821 |
DAB1 phosphorylation occurs solely in the segment spanning the 5th and 6th reelin repeats. |
| 12446734 |
This gene, is an intracellular adaptor of the Reelin pathway and reveals unusual complexity in human and mouse. |
| 16481437 |
After Reelin binds to the receptors, Disabled-1 becomes phosphorylated on tyrosine residues, initiating a signaling cascade that includes activation of Src-family kinases and Akt. | →View more information from publications. |
Recent Publications on DAB1: |  |
Epsilon haemoglobin specific antibodies with applications in noninvasive prenatal diagnosis.
Invasive procedures for prenatal diagnosis are associated with increased... | 7th October, 2009
| Department of Molecular Biology, University of Aarhus, Denmark.
| J Biomed Biotechnol. 2009;2009:659219. Epub 2009 Jul 14.
DOI Direct Link |
Downregulation of functional Reelin receptors in projection neurons implies that primary Reelin action occurs at early/premigratory stages.
Reelin signaling is essential for correct development of the mammalian... | 11th September, 2009
| Department of Biomedical Science, Graduate School of Pharmaceutical
| J Neurosci. 2009 Aug 26;29(34):10653-62.
DOI Direct Link |
IGF-I promotes neuronal migration and positioning in the olfactory bulb and the exit of neuroblasts from the subventricular zone.
While insulin-like growth factor-I (IGF-I) supports neuronal and glial... | 29th August, 2009
| Instituto Cajal, Consejo Superior de Investigaciones Cientificas, Madrid,
| Eur J Neurosci. 2009 Sep;30(5):742-55. Epub 2009 Aug 27.
DOI Direct Link |
Characterization and evolution of MHC class II B genes in Galapagos marine iguanas (Amblyrhynchus cristatus).
Major histocompatibility complex (MHC) class II molecules play a key role... | 12th August, 2009
| Department of Ecology and Evolutionary Biology, Yale University, New
| Dev Comp Immunol. 2009 Aug;33(8):939-47. Epub 2009 Apr 5.
DOI Direct Link |
Structure and evolution of a new avian MHC class II B gene in a sub-Antarctic seabird, the thin-billed prion (Procellariiformes: Pachyptila belcheri).
The major histocompatibility complex encodes molecules that present... | 11th August, 2009
| Department of Biology, University of Washington, Box 351800, Seattle, WA
| J Mol Evol. 2009 Mar;68(3):279-91. Epub 2009 Feb 10.
DOI Direct Link |
→View more research publications. |
DAB1 results (if any) from reagent suppliers | 
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