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DAB2
| Symbol: | DAB2 | | Name(s): | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | DOC-2, DOC2, FLJ26626 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18070591 |
These results suggest that Dab2 is a ligand dependent bi-directional regulator of ERK1,2 activity. |
| 17671122 |
Decreased DOC-2/DAB2 expression is associated with urothelial carcinoma of the bladder |
| 17115114 |
analysis of Dab2 protein loss and infrequent promoter hypermethylation in breast cancer |
| 11812785 |
mechanism of growth inhibitory effect in prostate cancer |
| 14669280 |
Loss in dab-2 expression is correlated with the loss of epithelial basement membrane in morphologically normal areas |
| 16061224 |
DAB2 expression during megakaryocytic differentiation expression is regulated by platelet-derived growth factor. |
| 16267015 |
DOC-2/DAB2 can modulate androgen receptor-mediated cell growth in both normal and malignant prostatic epithelial cells. |
| 14596919 |
CIN85 association with Dab2 is essential for its recruitment to clathrin coat and appears to be modulated by growth factor stimulation |
| 12805222 |
Results suggest that disabled-2 functions as a negative regulator of canonical Wnt signaling by stabilizing the beta-catenin degradation complex. |
| 12473651 |
DOC2 has a role in regulating c-Src in prostatic epithelium and cancer | →View more information from publications. |
Recent Publications on DAB2: |  |
Overexpression of myosin VI in prostate cancer cells enhances PSA and VEGF secretion, but has no effect on endocytosis.
Tissue expression microarrays, employed to determine the players and... | 27th October, 2009
| Cambridge Institute for Medical Research, University of Cambridge,
| Oncogene. 2009 Oct 26.
DOI Direct Link |
Structure characterization of lipocyclopeptide antibiotics, aspartocins A, B & C, by ESI-MSMS and ESI-nozzle-skimmer-MSMS.
Three lipocyclopeptide antibiotics, aspartocins A (1), B (2), and C (3),... | 20th October, 2009
| Wyeth Research, Chemical Technologies Section, Chemical Sciences Division,
| J Mass Spectrom. 2009 Oct 16.
DOI Direct Link |
Effect of IVF and laser zona dissection on DNA methylation pattern of mouse zygotes.
In vitro fertilization (IVF) and zona pellucida laser... | 14th October, 2009
| Institute of Experimental Genetics, Helmholtz Zentrum Munchen, German
| Mamm Genome. 2009 Oct 13.
DOI Direct Link |
Cargo binding induces dimerization of myosin VI.
Although myosin VI has properties that would allow it to function... | 7th October, 2009
| Department of Physiology, University of Pennsylvania School of Medicine,
| Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17320-4. Epub 2009 Sep 28.
DOI Direct Link |
Genomic response to Wnt signalling is highly context-dependent--evidence from DNA microarray and chromatin immunoprecipitation screens of Wnt/TCF targets.
Wnt proteins are important regulators of embryonic development, and... | 2nd October, 2009
| Oulu Centre for Cell Matrix Research, Biocenter Oulu, Laboratory of
| Exp Cell Res. 2009 Oct 1;315(16):2690-704. Epub 2009 Jun 27.
DOI Direct Link |
→View more research publications. |
DAB2 results (if any) from reagent suppliers | 
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