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DACH1


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Gene DB Home
Symbol:DACH1
Name(s):dachshund homolog 1 (Drosophila)
Type:protein-coding
Organism:Homo sapiens
Synonyms:DACH, FLJ10138
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
14525983 DACH1 bound to endogenous NCoR and Smad4 in cultured cells; Smad4 was required for DACH1 repression of TGF-beta induction of Smad signaling
12057194 forms an alpha/beta structure containing a DNA binding motif similar
15818552 The dachshund is required in mushroom body neurons for proper axon guidance and branching in Drosophila melanogaster.
14563999 identifed DACH enhancers in gene deserts
16980615 DACH1 repressed cyclin D1 through a novel mechanism via a c-Jun DNA-binding partner, requiring the DACH1 alpha-helical DS domain which recruits corepressors to the local chromatin.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDDachshund 1eyes absent 3--Pubmed
HPRDdachshund homolog 1 isoform aUbiquitin conjugating enzyme E2I--Pubmed
HPRDdachshund homolog 1 isoform aEyes absent 3--Pubmed
HPRDdachshund homolog 1 isoform aHomeobox protein SIX1--Pubmed
HPRDdachshund homolog 1 isoform amothers against decapentaplegic homolog 4--Pubmed
HPRDdachshund homolog 1 isoform amothers against decapentaplegic homolog 3--Pubmed
HPRDdachshund homolog 1 isoform anuclear receptor co-repressor 1--Pubmed
HPRDdachshund homolog 1 isoform atranscriptional co-repressor Sin3A--Pubmed

Recent Publications on DACH1:

Pubmed Logo
Molecular Characterization of Human Retinal Progenitor Cells.
Purpose: To examine the molecular profile of fetal human retinal...
26th June, 2009
Ophthalmology, The Schepens Eye Research Institute, Boston, Massachusetts, Invest Ophthalmol Vis Sci. 2009 Jun 24.
DOI Direct Link
The cell fate determination factor dachshund inhibits androgen receptor signaling and prostate cancer cellular growth.
Initially isolated as the dominant suppressor of the mutant epidermal...
20th June, 2009
Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson Cancer Res. 2009 Apr 15;69(8):3347-55. Epub 2009 Apr 7.
DOI Direct Link
Altered expression of DACH1 and cyclin D1 in endometrial cancer.
The altered expression of human DACH1, a Drosophila Dachshund homolog, has...
9th June, 2009
Department of Obstetrics and Gynecology, Qilu Hospital, Shandong Cancer Biol Ther. 2009 Aug;8(16):1534-9. Epub 2009 Aug 8.
Incidence and diversity of PAX5 fusion genes in childhood acute lymphoblastic leukemia.
PAX5, a master regulator of B-cell development, was recently shown to be...
7th February, 2009
Children's Cancer Research Institute, St Anna Kinderkrebsforschung, Leukemia. 2009 Jan;23(1):134-43. Epub 2008 Nov 20.
DOI Direct Link
Identification of prognostic biomarkers in gastric cancer using endoscopic biopsy samples.
Endoscopic biopsy prior to chemotherapy provides an opportunity for...
24th January, 2009
Medical Oncology, National Cancer Center Hospital, Tokyo, Japan. Cancer Sci. 2008 Nov;99(11):2193-9. Epub 2008 Jan 11.
DOI Direct Link

View more research publications.

DACH1 results (if any) from reagent suppliers

Google CSE Logo
DACH1 antibody (ab31588) | Abcam
Rabbit polyclonal to DACH1. DACH1 is similar to the Drosophila melanogaster dachshund gene, which encodes a nuclear factor essential for determining cell
...
http://www.abcam.com/DACH1-antibody-ab31588.html...

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DACH Antibody / DACH Antibodies
DACH1 (H-93) Antibody, sc-98563, rabbit IgG, 340-434 (h), WB, IP, IF, ... DACH1 (S-14) Antibody, sc-70258, rabbit IgG, Internal (h), WB, IF, ELISA, m, r, h ...
http://www.scbt.com/table-dach.html...

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DACH1 proteins and peptides: Cancer > Oncoproteins/suppressors ...
DACH1 proteins and peptides. ... Image Abreview Publication. ab31586 · DACH1 peptide · ab31587 · DACH1 peptide · Terms and conditions · Legal ...
http://www.abcam.com/index.html?t=123100&pt=2&c=4340&ei=&mu=...

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DACH1 (H-93) Antibody sc-98563
rabbit polyclonal IgG, 200µg/ml; epitope corresponding to amino acids 528-620 mapping within an internal region of DACH1 of human origin; recommended for ...
http://www.scbt.com/ko/datasheet-98563-dach1-h-93-antibody.h...

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D
HPA012672, Anti-DACH1 antibody produced in rabbit, affinity isolated antibody, human ... DACH1(1602), human, IHC (p), PA, pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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DACH1 (H-93) Antibody sc-98563
DACH1 (H-93) 抗体sc-98563 DACH1 (H-93) Antibody sc-98563.
http://www.scbt.com/zh/datasheet-98563-dach1-h-93-antibody.h...

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All DNA replication, Transcription, Translation and Splicing | Abcam
DACH1 antibody. IHC-P, WB. Images · Specific publication references. Rabbit polyclonal. Reacts with: Hu. Predicted: Ms, Rat, Chk. ab31586 · DACH1 peptide
...
http://www.abcam.com/index.html?pageconfig=catalog_byclass&i...

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