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CD55


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Symbol:CD55
Name(s):CD55 molecule, decay accelerating factor for complement (Cromer blood group)
Type:protein-coding
Organism:Homo sapiens
Synonyms:CR, DAF, TC
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16626483 Observational study of gene-disease association. (HuGE Navigator)
18165780 Role of the GPIIb/IIIa inhibitor tirofiban for the prevention of hDAF pig heart rejection and xenograft function.
16543227 A study evaluating whether H. pylori utilizes DAF as a receptor and the role of DAF within H. pylori-infected gastric mucosa is presented.
17893077 A fragment of DAF was used to determine its structure.
17449467 CD55 may simultaneously regulate both the innate and adaptive immune responses and can also regulate complement when bound to CD97.
16533428 CD55 has a role in prostate cancer growth and survival
15831949 swine vesicular disease virus isolates from early and recent outbreaks have been compared for their capacity to utilize the progenitor virus receptors coxsackie-adenovirus receptor and decay-accelerating factor
15808680 hDAF transgene blocks hyperacute graft rejection of porcie islets into alloxan diabetic ratsl
15808683 Hyperacute xenograft rejection of pig hearts into baboons was prevented by immunosorption and human DAF transgenic donor hearts.
15808686 Transgenic human DAF improves the performance of pig hearts by reducing myocardial damage and intravascular thrombosis after heart translpantation.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCD14decay accelerating factor for complement isoform 1 preproprotein--Pubmed
HPRDCD14 antigen precursorCD55--Pubmed
HPRDCD97 antigendecay accelerating factor for complement isoform 1 preproprotein--Pubmed
HPRDCD97 antigen isoform 1 precursorCD55--Pubmed
HPRDCD97 antigen isoform 1 precursorCromer blood group antigen--Pubmed
HPRDcomplement component receptor 1 isoform Sdecay accelerating factor for complement isoform 1 preproprotein--Pubmed
HPRDcomplement component receptor 1 isoform Sdecay accelerating factor for complement isoform 1 preproprotein--Pubmed
HPRDdecay accelerating factor for complement isoform 1 preproproteindecay accelerating factor for complement isoform 1 preproprotein--Pubmed
HPRDdecay accelerating factor for complement isoform 1 preproproteinglycosylphosphatidylinositol specific phospholipase D1 isoform 1 precursor--Pubmed
HPRDdecay accelerating factor for complement isoform 1 preproproteinglycosylphosphatidylinositol specific phospholipase D1 isoform 1 precursor--Pubmed

Recent Publications on CD55:

Pubmed Logo
Early expression changes of complement regulatory proteins (CRegs) and C5a receptor (CD88) on leukocytes after multiple injury in humans.
As a crucial element of innate immunity, the complement cascade becomes...
30th October, 2009
1Department of Traumatology, Hand-, Plastic- and Reconstructive Surgery Shock. 2009 Oct 27.
DOI Direct Link
Reduction of Neu5GC Xenoantigen on Human ADSC/MSCs lead to Them as Safer and More Useful Cell Sources for Realizing Various Stem Cell Therapies.
Adipose tissue is an attractive source for somatic stem cell therapy....
30th October, 2009
Foundation of Biomedical Research and Innovation, Department of Somatic Tissue Eng Part A. 2009 Oct 28.
DOI Direct Link
Maladaptation Of Critical Cellular Functions In Asthma: A Bioinformatic Analysis.
Small maladaptations in cellular response to environmental stressors may...
22nd October, 2009
Institute of Genomics & Integrative Biology. Physiol Genomics. 2009 Oct 20.
DOI Direct Link
Therapeutic implications of variable expression of CD52 on clonal cytotoxic T cells in CD8+ large granular lymphocyte leukemia.
BACKGROUND: T-cell large granular lymphocytic leukemia is a clonal...
2nd October, 2009
Department of Translational Hematology and Oncology Research, Taussig Haematologica. 2009 Oct;94(10):1407-14.
DOI Direct Link
Use of a FLAER-based WBC assay in the primary screening of PNH clones.
Diagnosis of paroxysmal nocturnal hemoglobinuria (PNH) with flow cytometry...
2nd October, 2009
Laboratory Medicine Program, Toronto General Hospital 11E-416, Toronto, Am J Clin Pathol. 2009 Oct;132(4):564-72.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Transfer of GPI-Linked Proteins to Transfused Patients With Paroxysmal Nocturnal Hemoglobinuria

Patents:

Patents logo
US Patent No.Title
7358059 Simultaneous quantification of PIG-A associated proteins in red cells, platelets and leukocyte subsets using a single measurement
7465572 De-immunized streptokinase
7473531 Pancreatic cancer targets and uses thereof
7485292 Method of treating a malignancy in a subject via direct picornaviral-mediated oncolysis
7485769 Transgenic mammals

View more patents.

CD55 results (if any) from reagent suppliers

Google CSE Logo
CD55 Antibody / CD55 Antibodies
CD55 Antibody / CD55 Antibodies. ... CD55 specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-cd55.html...

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The Abcam catalog
CD55 antibodies. ... CD55 antibody [143-30] (PE/Cy5). Flow Cyt, IHC-Fr. Mouse monoclonal ... CD55 antibody [BRIC 216]. Flow Cyt, IP. Mouse monoclonal ...
http://www.abcam.com/index.html?t=17&pt=1&c=505...

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CD55 (NaM16-4D3) Antibody sc-51733
Western blot analysis CD55 expression in PC-3 (A) and AML-193 (B) whole cell ... Western blot analysis of CD55 expression in non-transfected: sc-110760 (A) ...
http://www.scbt.com/datasheet-51733-cd55-nam16-4d3-antibody....

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human CD55 antibody, Affinity Purified conjugate
eBioscience technical data sheet for product 14-0559 Affinity Purified anti- human CD55 143-30 antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_14/14-...

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CD55 (H-319) Antibody sc-9156
See how others have used CD55 (H-319): sc-9156 antibody and or CD55 (H-319) ... Western blot analysis of CD55 expression in non-transfected: sc-110760 (A) ...
http://www.scbt.com/datasheet-9156-cd55-h-319-antibody.html...

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Anti-human CD55, Clone D17 mAb - Cell Sciences Products
CD55 expression increases upon T cell activation and in the presence of phorbol esters antibodies to CD55 (e.g. monoclonal antibody D17) are mitogenic. ...
http://www.cellsciences.com/content/p-detail.asp?rowid=7587...

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PE/Cy7 Anti-human CD55 Antibody Anti-CD55 - BioLegend
PE/Cy7 Anti-human CD55 Antibody Anti-CD55 - CD55 is a 60-70 kD glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein also known
as ...
http://www.biolegend.com/pe-cy7-anti-human-cd55-antibody-415...

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