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DAXX
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18003619 |
Data support a novel molecular function of Daxx as an upstream regulator of NHE1 in ischemic cell death. |
| 17389020 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17938171 |
Pin1-mediated prolyl isomerization plays an important role in the negative regulation of Daxx and thereby inhibits the oxidative stress-induced cellular apoptotic response, particularly in malignant tumor cells where Pin1 is often overexpressed. |
| 17942542 |
promyelocytic leukemia protein (PML) and hDaxx, mediate an intrinsic immune response against HCMV infection by contributing independently to the silencing of HCMV IE gene expression. |
| 17471023 |
Daxx may be an important predictive factor in cellular response to paclitaxel, which emphasizes a critical but unknown function of this protein in mitotic progression, which, when disabled, leads to survival advantages upon paclitaxel treatment. |
| 17947514 |
Viral IE gene expression is only observed upon cellular differentiation, suggesting little involvement of Daxx in the regulation of the human cytomegalovirus immediate-early (IE) gene expression in undifferentiated cells. |
| 17707345 |
Results indicate that the interaction of Daxx and dengue virus capsid protein involves in apoptosis of dengue virus-infected liver cells. |
| 17596307 |
Our work demonstrates that, in certain cell types, HCMV must silence its own gene expression to establish quiescence and prevent abortive infection and that the virus usurps a Daxx-mediated cellular intrinsic immune defense mechanism to do so. |
| 11799127 |
interaction with Pax5 resulting in transcriptional activation in B cells |
| 12968034 |
glucose deprivation activates the ASK1-SEK1-JNK1-HIPK1 pathway, relocalizing Daxx from the nucleus to the cytoplasm, where Daxx binds to ASK1, and subsequently leads to ASK1 oligomerization | →View more information from publications. |
Recent Publications on DAXX: |  |
Interactome for auxiliary splicing factor U2AF(65) suggests diverse roles.
U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) is an essential... | 31st October, 2009
| Department of Veterinary Molecular Biology, Montana State University,
| Biochim Biophys Acta. 2009 Jun-Aug;1789(6-8):487-92. Epub 2009 Jun 18.
DOI Direct Link |
Changing nuclear landscape and unique PML structures during early epigenetic transitions of human embryonic stem cells.
The complex nuclear structure of somatic cells is important to epigenomic... | 27th October, 2009
| Department of Cell Biology, University of Massachusetts Medical School,
| J Cell Biochem. 2009 Jul 1;107(4):609-21.
DOI Direct Link |
Stress-dependent Daxx-CHIP interaction suppresses the p53 apoptotic program.
Our previous studies have implicated CHIP (carboxyl terminus of... | 15th October, 2009
| Carolina Cardiovascular Biology Center, University of North Carolina,
| J Biol Chem. 2009 Jul 31;284(31):20649-59. Epub 2009 May 22.
DOI Direct Link |
End of the Daxx diatribe?
The complex nuclear structure of somatic cells is important to epigenomic... | 14th October, 2009
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| Cell Cycle. 2009 May 15;8(10):1467-8. Epub 2009 May 15.
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Daxx is a predominately nuclear protein that does not translocate to the cytoplasm in response to cell stress.
The intracellular translocation of Daxx to the cytoplasm is a phenomenon... | 14th October, 2009
| Cancer and Genetics Research Complex and Department of Anatomy and Cell
| Cell Cycle. 2009 May 15;8(10):1544-51. Epub 2009 May 10.
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→View more research publications. |
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