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DBC1


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Gene DB Home
Symbol:DBC1
Name(s):deleted in bladder cancer 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:DBCCR1, FAM5A
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12442002 DBCCR1 is involved in the process of bladder tumorigenesis
15746151 likely tumor suppressor for NSCLC;silencing through homozygous deletion or methylation of its promoter promotes progression
15643521 the prevalent inactivation of DBCCR1 seen at the expression level in astrocytomas is not primarily caused by genomic loss of the gene.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDDBCCR1acid sphingomyelinase-like phosphodiesterase 3A--Pubmed
HPRDdeleted in bladder cancer 1acid sphingomyelinase-like phosphodiesterase 3A--Pubmed

Recent Publications on DBC1:

Pubmed Logo
Interactions between DBC1 and SIRT 1 are deregulated in breast cancer cells.
Puf proteins control translation through the interaction of a C-terminal...
27th October, 2009
Department of Pharmacology, Kyung Hee University School of Medicine, Cell Cycle. 2009 Nov 11;8(22).
Expression of DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma.
PURPOSE: SIRT1 (silent mating-type information regulation 2 homologue 1)...
20th October, 2009
Departments of Pathology, Research Institute of Clinical Medicine and Clin Cancer Res. 2009 Jul 1;15(13):4453-9. Epub 2009 Jun 9.
DOI Direct Link
Distinct HIC1-SIRT1-p53 loop deregulation in lung squamous carcinoma and adenocarcinoma patients.
A HIC1-SIRT1-p53 circular loop in which hypermethylation in cancer 1...
10th October, 2009
Department of Pharmacology, National Cheng Kung University, Tainan 70101, Neoplasia. 2009 Aug;11(8):763-70.
A comprehensive microarray-based DNA methylation study of 367 hematological neoplasms.
BACKGROUND: Alterations in the DNA methylation pattern are a hallmark of...
15th September, 2009
Institute of Human Genetics, Christian-Albrechts University, Kiel, PLoS One. 2009 Sep 11;4(9):e6986.
DOI Direct Link
Integrative approach for prioritizing cancer genes in sporadic colon cancer.
The current multistep carcinogenesis models of colon cancer do not fully...
13th August, 2009
Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale Genes Chromosomes Cancer. 2009 Nov;48(11):953-62.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7571683 Electrical energy capture system with circuitry for blocking flow of undesirable electrical currents therein
6617936 Phase controlled oscillator
6615118 Hybrid energy power management system and method
6612246 Hybrid energy locomotive system and method
6612245 Locomotive energy tender

View more patents.

DBC1 results (if any) from reagent suppliers

Google CSE Logo
DBC1 antibody (ab57608) | Abcam
Mouse monoclonal to DBC1. The DBC1 (Deleted in breast cancer 1) amino terminus binds directly to the estrogen receptor alpha (ERalpha) hormone-binding ...
http://www.abcam.com/DBC1-antibody-ab57608.html...

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Phospho-DBC1 (Thr454) Antibody #4880
Western blot analysis of extracts from 293 and HeLa cell lines, untreated or UV- treated (100 J/m2 and 4 hour recovery), using Phospho-DBC1 (Thr454) Antibody ...
http://www.cellsignal.com/products/4880.html...

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DBC-1 (T-19) Antibody sc-54067
goat polyclonal IgG, 200µg/ml; epitope mapping within an internal region of DBC- 1 of human origin; recommended for detection of DBC-1 of m, r and h origin ...
http://www.scbt.com/datasheet-54067-dbc-1-t-19-antibody.html...

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Rabbit anti-DBC1 Antibody BL1924, affinity purified
Anti-DBC1 Antibody, Anti-DBC-1 Antibody, Anti-KIAA1967 Antibody, Anti- p30 DBC Antibody, Anti-p30DBC ... specific to DBC1 immobilized on solid support. ...
http://www.natutec.de/pdf_bethyl/A300-434A.pdf...

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DBC-1 (WQ7) Antibody sc-101228
DBC-1 (WQ7): sc-101228. Immunofluorescence staining of ... Western blot analysis of DBC-1 expression in non-transfected: sc-117752 (A) and human DBC-1 ...
http://www.scbt.com/datasheet-101228-dbc-1-wq7-antibody.html...

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Phospho-DBC1 (Thr454) Antibody
(DBC1) was originally identified by its localization to a region of chromosome 8p21 that is ... processing activates the pro-apoptotic activity of DBC1 ...
http://www.cellsignal.com/pdf/4880.pdf...

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DBC1 antibodies: Chromatin and Nuclear Signaling > Nuclear ...
DBC1 antibodies. ... DBC1 antibody. WB, ELISA. Images. Rabbit polyclonal. Reacts with: Hu. ab70239 · DBC1 antibody. IP, WB. Images. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=231662&pt=1&c=3397&ei=&mu=...

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