Monday November 23 2009 | Biotechnology feed | All feeds

DBN1

Symbol:	DBN1
Name(s):	drebrin 1
Type:	protein-coding
Organism:	Homo sapiens
Synonyms:	D0S117E, DKFZp434D064
Links:	Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications
Publication Link	Summary of findings
16780834	These data confirm the role of drebrin E2 in the formation of branching processes and further indicate that during cell migration, the protein contributes to retraction of the cell body and the tail but not to lamellipodia formation.
12009525	We found decreased levels of drebrin in frontal and temporal cortex from patients with DS and AD. Reduced drebrin could cause loss of spine plasticity in DS and may be a marker for neurodegenerative disorders.

Interacting gene products
Interaction Type	Gene 1	Gene 2	Interaction description	Complex	Publication Link
HPRD	Drebrin E	dynamin binding protein	-	-	Pubmed
HPRD	drebrin 1 isoform b	Dynamin binding protein	-	-	Pubmed
HPRD	drebrin 1 isoform b	MAP/ERK kinase kinase 3	-	-	Pubmed
HPRD	drebrin 1 isoform b	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	-	-	Pubmed
HPRD	drebrin 1 isoform b	Homer, neuronal immediate early gene, 2	-	-	Pubmed
HPRD	drebrin 1 isoform b	Homer, neuronal immediate early gene, 2	-	-	Pubmed
HPRD	drebrin 1 isoform b	receptor-interacting serine-threonine kinase 3	-	-	Pubmed

Patents:
US Patent No.	Title
7604936	Methods and compositions for diagnosis and monitoring auto immune and chronic inflammatory diseases
6936417	Gene expression in bladder tumors
6905827	Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
6841348	Methods for identifying and using maintenance genes
6753314	Protein-protein complexes and methods of using same
→View more patents.

DBN1 results (if any) from reagent suppliers

Drebrin (V-20) Antibody sc-30395 Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, DBN1, 1627, 5q35.3, NM_004395, ... http://www.scbt.com/datasheet-30395-drebrin-v-20-antibody.ht...
Drebrin siRNA (m) sc-63303 Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Dbn1, 56320, 13 B1, Q9QXS6 ... http://www.scbt.com/datasheet-63303-drebrin-sirna-m.html...
Drebrin (V-20) Antibody sc-30395 Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, DBN1, 1627, 5q35.3, NM_004395, ... http://www.scbt.com/ja/datasheet-30395-drebrin-v-20-antibody...
Drebrin (V-20) Antibody sc-30395 Spezies, Gen, Gen ID, Chromosomaler Locus, mRNA (Isoform) Accession #, Protein Accession #, OMIM™ Nummer. Human, DBN1, 1627, 5q35.3, NM_004395, NM_080881 ... http://www.scbt.com/de/datasheet-30395-drebrin-v-20-antibody...

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