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AP2B1


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Symbol:AP2B1
Name(s):adaptor-related protein complex 2, beta 1 subunit
Type:protein-coding
Organism:Homo sapiens
Synonyms:ADTB2, AP105B, AP2-BETA, CLAPB1, DKFZp781K0743
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16581796 AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization.
16903783 Clathrin, which interacts with the AP2beta-appendage, achieves ligand displacement in vivo by self-polymerisation as the coated pit matures.
14530274 the AP-2 complex is not associated with the endocytosed plasma membrane-associated clathrin
12900408 interactions of the EGF receptor with AP-2 mediated by the receptor 974YRAL and di-leucine motifs may contribute to beta2 tyrosine phosphorylation

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDadaptor-related protein complex 2, alpha 2 subunitAdaptor-related protein complex 2, beta 1 subunit--Pubmed
HPRDadaptor-related protein complex 2, alpha 2 subunitAdaptor-related protein complex 2, beta 1 subunit--Pubmed
HPRDAdaptor related protein complex 2 beta 1 subunitarrestin beta 1 isoform A--Pubmed
HPRDAdaptor related protein complex 2 beta 1 subunitadaptor-related protein complex 2, sigma 1 subunit isoform AP17--Pubmed
HPRDAdaptor related protein complex 2, beta 1 subunitadaptor-related protein complex 2, sigma 1 subunit isoform AP17--Pubmed
HPRDAdaptor related protein complex 2, beta 1 subunitadaptor-related protein complex 1, mu 2 subunit--Pubmed
HPRDAdaptor related protein complex 2, beta 1 subunitepsin 4--Pubmed
HPRDAdaptor-related protein complex 2, beta 1 subunitBeta arrestin 1--Pubmed
HPRDAdaptor-related protein complex 2, beta 1 subunitAP1M2--Pubmed
HPRDAdaptor-related protein complex 2, beta 1 subunitAP2S1--Pubmed

Recent Publications on AP2B1:

Pubmed Logo
Otitis media: a genome-wide linkage scan with evidence of susceptibility loci within the 17q12 and 10q22.3 regions.
BACKGROUND: Otitis media (OM) is a common worldwide pediatric health care...
26th September, 2009
Department of Human Genetics, Graduate School of Public Health, University BMC Med Genet. 2009 Sep 3;10:85.
DOI Direct Link

Patents:

Patents logo
US Patent No.Title
7612196 siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)
7579458 siRNA targeting synuclein, alpha (SNCA-1)
7579457 siRNA targeting carbonic anhydrase II
7576197 SiRNA targeting KRAS
7576196 siRNA targeting transducin (beta)-like 3 (TBL3)

View more patents.

AP2B1 results (if any) from reagent suppliers

Google CSE Logo
AP2B1 antibodies: Signal Transduction > Adapters > Cytoplasmic | Abcam
AP2B1 antibodies. ... Image Abreview Publication. ab75158 · AP2B1 antibody. WB, ELISA. Images. Rabbit polyclonal. Reacts with: Hu, Ms, Rat ...
http://www.abcam.com/index.html?t=272087&pt=1&c=2139&ei=&mu=...

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β-Adaptin (N-19) Antibody sc-6425
Human, AP2B1, 163, 17q12, NM_001030006, NM_001282 · P63010 · 601025. Mouse, Ap2b1, 71770, 11 C, Q9DBG3, N/A. Ordering Information ...
http://www.scbt.com/datasheet-6425-beta-adaptin-n-19-antibod...

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AP2M1 Recombinant Protein Adaptor-related protein complex 2 ...
SUBUNIT: Adaptor protein complex 2 (AP-2) is an heterotetramer composed of two large adaptins (α1A/AP2A1 or α1B/AP2A1 or α2/AP2A2 and β1/AP2B1), ...
http://www.prosci-inc.com/shop/catalog1/AP2M1-Recombinant-Pr...

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β-Adaptin (100/1) Antibody sc-58226
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, AP2B1, 163, 17q12, NM_001030006, ...
http://www.scbt.com/datasheet-58226-beta-adaptin-100-1-antib...

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Abcam antibodies and reagents product map
... AHNAK antibodies (2) · AKAP12 antibodies (5) · AKAP12 proteins and peptides (2) · AKAP13 antibodies (3) · AP1M2 antibodies (1) · AP2B1 antibodies (1) ...
http://www.abcam.com/index.html?cl=2105&pageconfig=productma...

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β-Adaptin (N-19) Antibody sc-6425
Human, AP2B1, 163, 17q12, NM_001030006, NM_001282 · P63010 · 601025. Mouse, Ap2b1, 71770, 11 C, Q9DBG3, 없음. 주문정보. 제품명, 카탈로그 번호, 단위, 가격
...
http://www.scbt.com/ko/datasheet-6425-beta-adaptin-n-19-anti...

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PhosphoSignature™
AP2B1. AP-2 complex subunit beta-1 (Beta-adaptin). P63010. 105. 276. DSDyYNMLLK. 2. 19. 2.0. 1.8-2.2. CSTB. Cystatin-B (Stefin-B) (Liver thiol proteinase ...
http://www.cellsignal.com/technologies/phosphoscan/pdfs/PSig...

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