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NQO1


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Symbol:NQO1
Name(s):NAD(P)H dehydrogenase, quinone 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:DHQU, DIA4, DTD, NMOR1, NMORI, QR1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18203021 Observational study of gene-disease association. (HuGE Navigator)
18214807 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18218609 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18225579 Observational study of gene-disease association. (HuGE Navigator)
18253865 Observational study of gene-disease association. (HuGE Navigator)
11051261 Observational study of gene-disease association. (HuGE Navigator)
11219774 Observational study of gene-disease association. (HuGE Navigator)
11319169 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
11520401 Observational study of gene-disease association. (HuGE Navigator)
11551408 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDNAD(P)H menadione oxidoreductase 1, dioxin-inducible isoform aNAD(P)H menadione oxidoreductase 1, dioxin-inducible isoform a--Pubmed
HPRDNAD(P)H menadione oxidoreductase 1, dioxin-inducible isoform aheat shock 70kDa protein 1A--Pubmed
HPRDNAD(P)H menadione oxidoreductase 1, dioxin-inducible isoform aheat shock 70kDa protein 1A--Pubmed

Recent Publications on NQO1:

Pubmed Logo
Synthesis and Biological Evaluation of Coumarin-Based Inhibitors of NAD(P)H: Quinone Oxidoreductase-1 (NQO1) (dagger).
The synthesis is reported here of two novel series of inhibitors of human...
3rd November, 2009
School of Pharmacy and Pharmaceutical Sciences. J Med Chem. 2009 Oct 30.
DOI Direct Link
Preparation of Disubstituted Phenyl Propargyl Alcohols, their Use in Oxathiolene Oxide Synthesis, and Evaluation of the Oxathiolene Oxide Products as Anticarcinogenic Enzyme Inducers.
A number of alkynols have been prepared by Sonogoshira coupling of...
30th October, 2009
Department of Chemistry, Wake Forest University, P.O. Box 7486, Lett Org Chem. 2009 Apr 1;6(3):242-251.
DOI Direct Link
Isoalantolactone from Inula helenium caused Nrf2-mediated induction of detoxifying enzymes.
Our previous study demonstrated that methanolic extract of Inula helenium...
28th October, 2009
Department of Animal Science and Biotechnology and School of Applied J Med Food. 2009 Oct;12(5):1038-45.
DOI Direct Link
Targeting CWR22Rv1 prostate cancer cell proliferation and gene expression by combinations of the phytochemicals EGCG, genistein and quercetin.
Prostate cancer (CaP) is a significant cause of death in American men....
23rd October, 2009
Department of Biochemistry and Molecular Biology, New York Medical Anticancer Res. 2009 Oct;29(10):4025-32.
Effects of quercetin and catechin on hepatic glutathione-S transferase (GST), NAD(P)H quinone oxidoreductase 1 (NQO1), and antioxidant enzyme activity levels in rats.
Cell culture data indicate that quercetin and catechin may affect the...
20th October, 2009
Christian-Albrechts-University, Kiel, Germany. Nutr Cancer. 2009;61(5):717-22.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Protection Against Benzene Toxicity

Patents:

Patents logo
US Patent No.Title
7608613 Analogs of benzoquinone-containing ansamycins and methods of use thereof
7247714 Protection against oxidative stress and inflammation by a cytoprotective response element
7141372 Universal RT-coupled PCR method for the specific amplification of mRNA
7138122 Therapeutic systems
7112668 Polypeptides and nucleic acids encoded thereby

View more patents.

NQO1 results (if any) from reagent suppliers

Google CSE Logo
NQO1 antibody (ab2346) | Abcam
Goat polyclonal to NQO1. NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase.
http://www.abcam.com/NQO1-antibody-ab2346.html...

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NQO1 (A180) Antibody sc-32793
See how others have used NQO1 (A180): sc-32793 antibody and or NQO1 (A180) ... Western blot analysis of NQO1 expression in non-transfected: sc-117752 (A) ...
http://www.scbt.com/datasheet-32793-nqo1-a180-antibody.html...

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NQO1 monoclonal antibody (M01)
Immunofluorescence of monoclonal antibody to NQO1 (AT3089a) on HepG2 cell . ... Western blot analysis of NQO1 over-expressed 293 cell line, ...
http://www.abgent.com/products/catalog_no/AT3089a_NQO1_monoc...

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NQO1 (C-19) Antibody sc-16464
See how others have used NQO1 (C-19): sc-16464 antibody and or NQO1 (C-19) ... Western blot analysis of NQO1 expression in Hep G2 whole cell lysate. ...
http://www.scbt.com/datasheet-16464-nqo1-c-19-antibody.html...

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NQO1 antibodies: Signal Transduction > Metabolism > Drug ...
NQO1 antibodies. ... NQO1 antibody [A180]. IHC-P, WB, IP. Mouse monoclonal. Reacts with: Hu, Rat. ab28947 · NQO1 antibody [A180]. IHC-P, WB, ICC/IF, sELISA,
...
http://www.abcam.com/index.html?t=5025&pt=1&c=3613&ei=&mu=ra...

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NQO1 (H-90) Antibody sc-25591
Western blot analysis of NQO1 expression in Hep G2 whole cell lysate. sc-25591. NQO1 (H-90): sc-25591. Immunofluorescence staining of normal mouse intestine ...
http://www.scbt.com/datasheet-25591-nqo1-h-90-antibody.html...

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NQO1 (A180) Mouse mAb #3187
The expression of NQO1 is increased in liver, colon and breast tumors and non- small cell lung cancer (NSCLC) compared with the normal tissues (1,2). ...
http://www.cellsignal.com/products/3187.html...

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