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DLG3

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Symbol:	DLG3
Name(s):	discs, large homolog 3 (neuroendocrine-dlg, Drosophila)
Type:	protein-coding
Organism:	Homo sapiens
Synonyms:	KIAA1232, MRX, MRX90, NE-Dlg, NEDLG, SAP102
Links:	Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications
Publication Link	Summary of findings
16482544	E6AP is extensively involved in the ubiquitin-mediated degradation of Dlg (an HPV E6-dependent substrate) as a cellular E3 ubiquitin-protein ligase.
15185169	Loss may lead to altered synaptic plasticity and may explain the intellectual impairment observed in individuals with DLG3 mutations

Interacting gene products
Interaction Type	Gene 1	Gene 2	Interaction description	Complex	Publication Link
HPRD	ATPase, Ca++ transporting, plasma membrane 4	synapse-associated protein 102	-	-	Pubmed
HPRD	ATPase, Ca++ transporting, plasma membrane 4	synapse-associated protein 102	-	-	Pubmed
BIND	plasma membrane calcium ATPase 4 isoform 4b	synapse-associated protein 102	PMCA4b interacts with SAP102. This interaction was modeled on a demonstrated interaction between human PMCA4b and SAP102 from rat and an unspecified source.	-	Pubmed
HPRD	Synapse associated protein 97	synapse-associated protein 102	-	-	Pubmed
HPRD	discs, large homolog 1	Synapse associated protein 102	-	-	Pubmed
HPRD	Synapse associated protein 102	N-methyl-D-aspartate receptor subunit 2A precursor	-	-	Pubmed
HPRD	Synapse associated protein 102	N-methyl-D-aspartate receptor subunit 2B precursor	-	-	Pubmed
HPRD	Synapse associated protein 102	N-methyl-D-aspartate receptor subunit 2C precursor	-	-	Pubmed
HPRD	Synapse associated protein 102	guanylate cyclase 1, soluble, alpha 2	-	-	Pubmed
HPRD	Synapse associated protein 102	guanine deaminase	-	-	Pubmed

Recent Publications on DLG3:
Tumor suppressor CADM1 is involved in epithelial cell structure. The tumor suppressor, CADM1, is involved in cell adhesion and...	27th October, 2009	Division of Molecular Pathology, Institute of Medical Science, The	Biochem Biophys Res Commun. 2009 Oct 23. DOI Direct Link
A novel mutation in the DLG3 gene encoding the synapse-associated protein 102 (SAP102) causes non-syndromic mental retardation. We have identified a novel splice site mutation (IVS6-1G > A) in the...	2nd October, 2009	Institut Cochin, Universite Paris Descartes, INSERM, CNRS UMR 8104, CHU	Neurogenetics. 2009 Oct 1. DOI Direct Link
DLG3/SAP102 protein expression in malformations of cortical development: a study of human epileptic cortex by tissue microarray. The human DLG3 gene encodes the synapse-associated protein 102 (SAP102),...	23rd May, 2009	Department of Neuroscience, Neurology, Uppsala University Hospital,	Epilepsy Res. 2009 Mar;84(1):33-41. Epub 2009 Jan 23. DOI Direct Link
Lamina-specific abnormalities of NMDA receptor-associated postsynaptic protein transcripts in the prefrontal cortex in schizophrenia and bipolar disorder. The hypothesis of N-methyl-D-aspartate (NMDA) receptor hypofunction in...	9th October, 2008	Department of Psychiatry and Behavioral Neurobiology, University of	Neuropsychopharmacology. 2008 Aug;33(9):2175-86. Epub 2007 Nov 21. DOI Direct Link
[Non-specific X-linked mental retardation] INTRODUCTION: Non-specific mental retardation is defined by the absence of...	18th June, 2008	Hospital Universitario	Rev Neurol. 2006 Jan 7;42 Suppl 1:S77-83.
→View more research publications.

Patents:
US Patent No.	Title
7599933	Coupled two-way clustering analysis of data
6324287	Pad encryption method and software
6563519	Information processing apparatus, information processing method, information processing program for performing output setup to device apparatus, and memory medium storing such program therein
6653102	Nucleic acid encoding a phosphatase 2C that interacts with Fe 65
6787641	Identification of sel-12 and uses thereof
→View more patents.

DLG3 results (if any) from reagent suppliers

D HPA001733, Anti-DLG3 antibody produced in rabbit, affinity isolated antibody, human ... DLG3(1741), human, IHC (p), PA, pricing ... https://www.sigmaaldrich.com/etc/controller/controller-page....
SAP 102 SAP 102 (DLG 3). A component of postsynaptic densities ... Cytohesins · D 12 · D -28k · Densin 180 · DLG 1 · DLG 2; DLG 3; DLG 4 · DLG 6 · DNPI · Dynamins ... http://www.sysy.com/products/sap102/index.php?n=DLG3...
NE-dlg (N-19) Antibody sc-6925 Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, DLG3, 1741, Xq13.1, NM_021120 ... http://www.scbt.com/datasheet-6925-ne-dlg-n-19-antibody.html...
SAP102 (G670) Antibody #3733 Synapse-associated protein 102 (SAP102, DLG3) belongs to the membrane-associated guanylate kinase (MAGUK) protein family and is a homolog of the Drosophila ... http://www.cellsignal.com/products/3733.html...
MPP3 monoclonal antibody (M01) DLG3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3). Application Data: Calculated MW: 66152 Da. MPP3 monoclonal antibody (M01) ... http://www.abgent.com/products/catalog_no/AT2895a_MPP3_monoc...
SAP102 (G670) Antibody DLG3) belongs to the membrane-associated guanylate kinase (MAGUK) protein family and is a homolog of the. Drosophila disc large (dlg) tumor suppressor ... http://www.cellsignal.com/pdf/3733.pdf...
S4687 Anti-SAP-102 antibody produced in rabbit IgG fraction of ... application(s), immunoblotting: suitable. immunohistochemistry: suitable. Gene Information, rat ... Dlg3(58948). shipped in, dry ice. storage temp. −20°C ... http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=S468...

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DLG3

Gene Information from Publications

Interacting gene products

Recent Publications on DLG3:

Patents:

DLG3 results (if any) from reagent suppliers