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AGER


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Gene DB Home
Symbol:AGER
Name(s):advanced glycosylation end product-specific receptor
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC22357, RAGE
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18279703 RAGE could also behave as a receptor for Mycobacterium tuberculosis
18279705 -374T/A RAGE polymorphism is an independent protective factor for cardiac events in nondiabetic patients with coronary artery disease
17560613 Olmesartan may play a protective role against proliferative diabetic retinopathy by attenuating the deleterious effects of AGEs via down-regulation of RAGE.
16728681 Observational study of gene-disease association. (HuGE Navigator)
17345061 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
17355942 Observational study of gene-disease association. (HuGE Navigator)
17700210 Observational study of gene-disease association. (HuGE Navigator)
18080716 HCC during the early stage of tumorigenesis with less blood supply may acquire resistance to stringent hypoxic milieu by hypoxia-induced RAGE expression.
18179750 the -374AA genotype of the RAGE gene promoter could be associated with a reduced risk of in-stent restenosis after coronary stent implantation
18046662 Plasma soluble RAGE and endogenous secretory RAGE are not associated with measures of diabetic neuropathy in type 2 diabetes patients.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDRAGEhigh-mobility group box 1--Pubmed
HPRDRAGES100 calcium-binding protein A12--Pubmed
HPRDadvanced glycosylation end product-specific receptor isoform 1 precursorHigh mobility group box 1--Pubmed
HPRDadvanced glycosylation end product-specific receptor isoform 1 precursorCalgranulin C--Pubmed
HPRDadvanced glycosylation end product-specific receptor isoform 1 precursorS100 calcium binding protein, beta--Pubmed
HPRDadvanced glycosylation end product-specific receptor isoform 1 precursorS100 alpha--Pubmed
HPRDadvanced glycosylation end product-specific receptor isoform 1 precursorS100 calcium binding protein P--Pubmed
HPRDadvanced glycosylation end product-specific receptor isoform 1 precursorS100 calcium binding protein P--Pubmed
HPRDadvanced glycosylation end product-specific receptor isoform 1 precursorelongation protein 3 homolog--Pubmed
HPRDadvanced glycosylation end product-specific receptor isoform 1 precursorelongation protein 3 homolog--Pubmed

Recent Publications on AGER:

Pubmed Logo
Reduced size-independent mechanical properties of cortical bone in high-fat diet-induced obesity.
Overweight and obesity are rapidly expanding health problems in children...
27th October, 2009
Materials Sciences Division, Lawrence Berkeley National Laboratory, Bone. 2009 Oct 21.
DOI Direct Link
Radiological and multi-element analysis of sediments from the Proserpina reservoir (Spain) dating from Roman times.
The Proserpina dam was built in Roman times to provide drinking water to...
22nd October, 2009
LARUEX, Department of Applied Physics, Faculty of Veterinary, University J Environ Radioact. 2009 Oct;100(10):866-74. Epub 2009 Jul 24.
DOI Direct Link
Noninvasive detection of lung cancer by analysis of exhaled breath.
BACKGROUND: Lung cancer is one of the leading causes of death in Europe...
1st October, 2009
Department of Operative Medicine, Innsbruck Medical University, A-6020 BMC Cancer. 2009 Sep 29;9:348.
DOI Direct Link
Changes in weather and the effects on pediatric asthma exacerbations.
BACKGROUND: Pediatric asthma exacerbations may correlate with changes in...
1st October, 2009
Division of Allergy and Immunology; Children's Hospital of Michigan, Wayne Ann Allergy Asthma Immunol. 2009 Sep;103(3):220-4.
The Role of the Complement System and the Activation Fragment C5a in the Central Nervous System.
The complement system is a pivotal component of the innate immune system...
19th September, 2009
School of Biomedical Sciences, University of Queensland, St. Lucia, Neuromolecular Med. 2009 Sep 11.
DOI Direct Link

View more research publications.

BioNews Results for AGER

: RSS Logo
BioPortfolio Logo
EDCO Presents 2009 Awards to Agere Pharmaceuticals, Others
I Stock Analyst:  Oct 29 2009 5:53PM Matching: ager
EDCO presents 2009 awards to Agere Pharmaceuticals, others
Oregonian:  Oct 29 2009 2:17PM Matching: ager
Genetic variation for resistance to ear rots and mycotoxins contamination in early European maize inbred lines
Environmental Expert:  Oct 29 2009 9:03AM Matching: ager
Helix Hearing Care Centre and RA Centre host Healthy Aging Day
News-Medical.Net:  Oct 28 2009 9:15AM Matching: ager
Healthy Aging Day: a wonderful venue for encouraging sound hearing among Ottawa's seniors
CNW Telbec:  Oct 27 2009 6:20PM Matching: ager
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Pregnancy in Polycystic Ovary Syndrome II

Patents:

Patents logo
US Patent No.Title
7465830 Method of preparing pseudonorephedrine
7511028 Use of bisphosphonates for otosclerosis
7513215 Systems and methods for the production of highly tetrahedral amorphous carbon coatings
7528137 Compounds, compositions, and methods
7531695 Therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders

View more patents.

AGER results (if any) from reagent suppliers

Google CSE Logo
RAGE (AGER) Antibody (N-term)
Advanced glycosylation end product-specific receptor [Precursor]; Receptor for advanced glycosylation end products; AGER; RAGE ...
http://www.abgent.com/products/catalog_no/AP2401a_RAGE_AGER_...

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AV41642 Anti-AGER (AB1) antibody produced in rabbit affinity ...
AV41642 Anti-AGER (AB1) antibody produced in rabbit affinity isolated antibody, lyophilized powder.
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=AV41...

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RAGE (D-5) Antibody sc-74535
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, AGER, 177, 6p21.32, NM_001136, ...
http://www.scbt.com/datasheet-74535-rage-d-5-antibody.html...

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Promega Notes 95: A Polyclonal HaloTag Antibody for Western ...
ager (GE HealthCare) using a 543nm laser and a 580/30 bandpass emission filter. Lane 1, DyLightâ„¢ molecular weight markers (Pierce). ...
http://www.promega.com/pnotes/95/14867_23/14867_23.pdf...

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IGF-II (F-20) Antibody sc-7435
Ager, EI. et al. 2008. Expression and protein localisation of IGF2 in the marsupial placenta. BMC Dev. Biol. 8: -. View PubMed Entry. Watanabe, Y. et al.
...
http://www.scbt.com/datasheet-7435-igf-ii-f-20-antibody.html...

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Human RAGE MAb (Clone 176902)
RAGE, also named AGER (Advanced Glycosylation End Product-specific. Receptor), is a member of the immunoglobulin superfamily. It binds multiple ligands ...
http://www.rndsystems.com/pdf/MAB11451.pdf...

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A Phosphorylation State-specific Antibody Recognizes Hsp27, a ...
ager. Each spot was quantitated and is tabulated such that intensity is expressed as a percentage of background phospho- rylation. ...
http://www.cellsignal.com/technologies/pdfs/A_Phosphorylatio...

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