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HBEGF
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17717322 |
HB-EGF regulated epithelial repair is enhanced by IL-13 from airway epithelial cells |
| 17928891 |
alters the phenotype of keratinocytes in a manner similar to that observed during epidermal repair |
| 17962208 |
HBEGF was present in almost all breast cancers studied. High expression is related to the biological aggressiveness of breast cancer. |
| 17637826 |
activation of PPARdelta is a major event in psoriasis, contributing to the hyperproliferative phenotype by induction of HB-EGF. |
| 17855771 |
Juxtacrine activation of EGFR by membrane-anchored HB-EGF may play an important role in the regulation of tight junction proteins and transepithelial resistance. |
| 17525275 |
HB-EGF is up-regulated in tumor cells of SCC but not BCC of the skin. HB-EGF is also overexpressed in asymptomatic epidermis adjacent to both SCC and BCC, relative to normal skin. |
| 16470170 |
HB-EGF and amphiregulin mediate retinoic-acid induced epidermal hyperplasia |
| 17548351 |
Gbetagamma mediates UVB-induced human keratinocyte apoptosis by augmenting the ectodomain shedding of HB-EGF, which sequentially activates EGFR and p38 |
| 12835543 |
HB-EGF has an important role in the early pathogenesis of psoriasis. |
| 16407398 |
A post-transcriptional mechanism induced in trophoblasts by low O(2) rapidly amplifies HBEGF signaling to inhibit apoptosis. | →View more information from publications. |
Recent Publications on HBEGF: |  |
Gene expression profiling of TGFbeta2- and/or BMP7-treated trabecular meshwork cells: Identification of Smad7 as a critical inhibitor of TGF-beta2 signaling.
A distinct structural change in the trabecular meshwork (TM) of patients... | 9th October, 2009
| Institute of Human Anatomy and Embryology, University of Regensburg,
| Exp Eye Res. 2009 Jun;88(6):1020-32. Epub 2009 Jan 18.
DOI Direct Link |
KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin.
A key initial event in hair follicle morphogenesis is the localised... | 22nd September, 2009
| School of Biological and Biomedical Sciences, University of Durham, Durham
| Development. 2009 Jul;136(13):2153-64. Epub 2009 May 27.
DOI Direct Link |
Genes that mediate breast cancer metastasis to the brain.
The molecular basis for breast cancer metastasis to the brain is largely... | 13th August, 2009
| Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer
| Nature. 2009 Jun 18;459(7249):1005-9. Epub 2009 May 6.
DOI Direct Link |
Molecular signature of cell cycle exit induced in human T lymphoblasts by IL-2 withdrawal.
BACKGROUND: The molecular mechanisms of cell cycle exit are poorly... | 25th July, 2009
| Department of Immunology, Maria Sklodowska-Curie Memorial Cancer Centre
| BMC Genomics. 2009 Jun 8;10:261.
DOI Direct Link |
Differential regulation of betacellulin and heparin-binding EGF-like growth factor in cultured zebrafish ovarian follicle cells by EGF family ligands.
Recently the roles of epidermal growth factor (EGF) family ligands in... | 18th July, 2009
| Department of Biology, The Chinese University of Hong Kong, Shatin, New
| Comp Biochem Physiol A Mol Integr Physiol. 2009 May;153(1):13-7. Epub 2008
DOI Direct Link |
→View more research publications. |
HBEGF results (if any) from reagent suppliers | 
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