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AGTR1


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Symbol:AGTR1
Name(s):angiotensin II receptor, type 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18202720 These results show that the AT(1) receptor undergoes a conformational switch that couples mechanical stress-induced activation and inverse agonist-induced inactivation.
18205094 Observational study of gene-disease association. (HuGE Navigator)
18231736 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18239157 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18239384 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18260840 Observational study of gene-disease association. (HuGE Navigator)
18261537 Clinical trial of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18328310 Observational study of gene-disease association. (HuGE Navigator)
18347611 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18006496 beta-arrestin2 supported protein kinase C-independent ERK1/2 activation by the AT1a rceptor

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDangiotensinogen preproproteinangiotensin II receptor, type 1--Pubmed
HPRDangiotensinogen preproproteinangiotensin II receptor, type 1--Pubmed
HPRDAngiotensin receptor 1bradykinin receptor B2--Pubmed
HPRDAngiotensin receptor 1RAB5A, member RAS oncogene family--Pubmed
HPRDAngiotensin receptor 1arrestin, beta 2 isoform 1--Pubmed
HPRDAngiotensin receptor 1Janus kinase 2--Pubmed
HPRDangiotensin II receptor, type 1Janus kinase 2--Pubmed
HPRDangiotensin II receptor, type 1Bradykinin receptor 2--Pubmed
HPRDangiotensin II receptor, type 1Beta arrestin 2--Pubmed
HPRDangiotensin II receptor, type 1Ras related protein Rab 5A--Pubmed

Recent Publications on AGTR1:

Pubmed Logo
Bone Marrow AT1 Augments Neointima Formation by Promoting Mobilization of Smooth Muscle Progenitors via Platelet-Derived SDF-1{alpha}
OBJECTIVE: Bone marrow (BM)-derived endothelial progenitor cells (EPCs)...
17th October, 2009
Department of Cardiovascular Medicine, Kyoto Prefectural University School Arterioscler Thromb Vasc Biol. 2009 Oct 15.
DOI Direct Link
Haplotype-based case-control study of the human agtr1 gene and essential hypertension in Han Chinese subjects.
OBJECTIVES: Essential hypertension is considered to be a multifactorial...
17th October, 2009
Human Genetics Center of Yunnan University, #2 N. Cuihu Rd. Kunming, Clin Biochem. 2009 Oct 13.
DOI Direct Link
Bone marrow angiotensin AT1 receptor regulates differentiation of monocyte lineage progenitors from hematopoietic stem cells.
BACKGROUND: The angiotensin II (Ang II) type 1 (AT(1)) receptor is...
30th September, 2009
Department of Cardiovascular Medicine, Kyoto Prefectural University School Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1529-36. Epub 2009 Jul 23.
DOI Direct Link
Multilocus analysis in candidate genes ACE, AGT, and AGTR1 and predisposition to peripheral arterial disease: Role of ACE D/-240T haplotype.
OBJECTIVE: Peripheral arterial disease (PAD) is a common manifestation of...
29th September, 2009
Department of Medical and Surgical Critical Care, Thrombosis Centre, J Vasc Surg. 2009 Sep 24.
DOI Direct Link
Analysis of polymorphism in renin angiotensin system and other related genes in South Indian chronic kidney disease patients.
BACKGROUND: Several Renin Angiotensin System (RAS) polymorphisms alter the...
24th September, 2009
Department of Biochemistry, School of Biological Sciences, Madurai Kamaraj Clin Chim Acta. 2009 Aug;406(1-2):108-12. Epub 2009 Jun 9.
DOI Direct Link

View more research publications.

BioNews Results for AGTR1

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Blood pressure drug blocks breast cancer gene
Homemakers.com:  Oct 22 2009 10:56PM Matching: agtr1
An existing drug called losartan, shrank breast cancer tumours in lab studies. Find out why researchers are ho
Homemakers.com:  Oct 21 2009 5:20PM Matching: agtr1
October health news: Blood pressure drug blocks breast cancer gene
Homemakers.com:  Oct 16 2009 5:23AM Matching: agtr1
Compendia Bioscience Announces the Release of Oncomine 4 Research Edition
U.S. Newswire:  Sep 23 2009 7:56PM Matching: agtr1

Clinical Trials:

Clinical Trials Logo
Effects of Sodium Intake on (PK/PD) Relationship of a Single Dose of a Renin Angiotensin System-Blocker

Patents:

Patents logo
US Patent No.Title
7592325 Methods and compositions for the treatment of eye disorders with increased intraocular pressure
6727063 Single nucleotide polymorphisms in genes
6969702 Compounds and methods for increasing neurogenesis
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
7291461 Methods for identifying small molecules that modulate premature translation termination and nonsense mRNA decay

View more patents.

AGTR1 results (if any) from reagent suppliers

Google CSE Logo
AGTR1 Antibody AGTR1 / AT1
AGTR1 antibody was raised against a synthetic peptide of AGTR1.,
http://www.prosci-inc.com/shop/catalog1/AGTR1-Antibody-p-262...

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Angiotensin II Type 1 Receptor antibody (ab47162) reviews | Abcam
I have given this antibody a 5* rating because I believe ALL of the major bands detected by this antibody are modified forms of AGTR1, including those ...
http://www.abcam.com/index.html?pageconfig=reviews&intAbID=4...

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Infectious Disease Antibodies :: Page 1
Aflatoxin Antibody, 35-560, Fu, E, Recognizes aflatoxins B1 and B2 of Aspergillus flavus. AGTR1 Antibody, 45-216, H, M, R, E, WB, AGTR1 / AT1 ...
http://www.prosci-inc.com/shop/catalog1/Infectious-Disease-A...

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Anti-Angiotensin Receptor 1 Polyclonal Antibody
GB-30074 detects AGTR1 in human samples. GB-30074 has been successfully used in ELISA ... AGTR1 may play role in the generation of reperfusion arrhythmias ...
http://www.bioreagents.com/products/productDetails/productDe...

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Cancer Antibodies :: Page 3
AGTR1 Antibody, 45-216, H, M, R, E, WB, AGTR1 / AT1. Ah Receptor Antibody, 48- 197, H, IHC, Ah Receptor. Ah Receptor Antibody, 48-198, H, IHC, Ah Receptor ...
http://www.prosci-inc.com/shop/catalog1/Cancer-Antibodies-p-...

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AT1 (306) Antibody sc-579
Human, AGTR1, 185, 3q24, NM_000685, NM_004835, NM_009585, NM_031850, NM_032049 · P30556 · 267430. Mouse, Agtr1a, 11607, 13 A3.2, P29754 ...
http://www.scbt.com/datasheet-579-at1-306-antibody.html...

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Anti-Angiotensin II Receptor Type-1 (extracellular)-ATTO-550
1 Aug 2007 ... Anti-Angiotensin II Receptor Type-1 (extracellular)-ATTO-550. (AT1 Receptor, AGTR1). Product #: AAR-011-AO. Current Lot #: AN-01 ...
http://www.alomone.com/system/UpLoadFiles/DGallery/Docs/AAR-...

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