|
| |
E2F6
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17908821 |
E2F6 binding sites are located within 2 kb of a transcription start site, in both normal and tumor cells |
| 17600109 |
E2F-6 inhibited Apaf-1 upregulation by competing with E2F-1 for promoter binding. It enhanced the clonogenic growth of granulocyte, erythroid, macrophage, & megakaryocyte cells.It may prevent hematopoietic progenitor cell loss during proliferation. |
| 12909625 |
results suggest that E2F6 represses transcription of the brca1, ctip, art27, hp1alpha, and the rbap48 genes and depletion of E2F6 resulted in the recruitment of E2F1 to the target promoters |
| 15536069 |
showed that E2F6, DP1, EPC1, EZH2, and Sin3B co-elute, suggesting the identification of a novel E2F6 complex that exists in vivo in both normal and transformed human cell lines |
| 15081404 |
contains nine exons distributed along 20.4kbp of genomic DNA on chromosome 2 leading to the transcription of six alternatively spliced E2F6 mRNAs that encode four different E2F6 proteins |
| 12004135 |
data suggest that E2F- and Myc-responsive genes are coregulated by E2F6 complex in quiescent cells |
| 16107498 |
the expression of the E2F6 repressor is influenced at the transcriptional level by E2F family members and suggest that interplay among these transcriptional regulators, especially E2F1, may be critical for cell cycle regulation |
| 15574595 |
functions as a repressor of E2F-dependent transcription during S phase |
| 15474455 |
E2F6 does not contain the domains required for modulation of squamous differentiation |
| 17001316 |
PHC3 and E2F6 showed nuclear colocalization in a punctate pattern which was not seen in proliferating cells suggesting that PHC3 may be part of an E2F6-polycomb complex that has been shown to occupy and silence target promoters in G(0) | →View more information from publications. |
Recent Publications on E2F6: |  |
Identification of aberrant cell cycle regulation in Epstein-Barr virus-associated nasopharyngeal carcinoma by cDNA microarray and gene set enrichment analysis.
Previous studies have revealed that Epstein-Barr virus (EBV) was closely... | 19th September, 2009
| Cancer Research Institute, Xiangya School of Medicine, Central South
| Acta Biochim Biophys Sin (Shanghai). 2009 May;41(5):414-28.
|
An essential role for DNA methyltransferase 3a in melanoma tumorigenesis.
Abnormal DNA methylation and associated silencing of tumor suppressor... | 2nd September, 2009
| Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell
| Biochem Biophys Res Commun. 2009 Sep 25;387(3):611-6. Epub 2009 Jul 24.
DOI Direct Link |
CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors.
To understand the mechanism of transcriptional down-regulation of BRCA1 by... | 26th May, 2009
| Department of Medicine, Center for Clinical Cancer Genetics, University of
| Breast Cancer Res Treat. 2009 May 23.
DOI Direct Link |
Alteration of gene expression during nasopharyngeal carcinogenesis revealed by oligonucleotide microarray after microdissection of tumor tissue and normal epithelia from nasopharynx.
BACKGROUND: Microarray and microdissection techniques were being used for... | 23rd May, 2009
| Department of Otolaryngology Head and Neck Surgery Peking University Third
| Chin Med J (Engl). 2009 Feb 20;122(4):437-43.
|
E2F6 inhibits cobalt chloride-mimetic hypoxia-induced apoptosis through E2F1.
E2F6, a potent transcriptional repressor, plays important roles in cell... | 28th February, 2009
| Laboratory of Molecular Cardiology, Institute of Health Sciences, Shanghai
| Mol Biol Cell. 2008 Sep;19(9):3691-700. Epub 2008 Jun 18.
DOI Direct Link |
→View more research publications. |
E2F6 results (if any) from reagent suppliers | 
|
E2F6 antibody [TFE61] (ab11952) | Abcam
Mouse monoclonal [TFE61] to E2F6. The E2F6 gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in
...
http://www.abcam.com/E2F6-antibody-TFE61-ab11952.html...
|
 |
Protein Modification - Methylation Antibody
AT1837aNEW, E2F6 monoclonal antibody (M01), ELISA,S-ELISA,WB-Re, H. AT1838aNEW, E2F6 monoclonal antibody (M02), ELISA,IF,S-ELISA,WB-Ce,WB-Re, H ...
http://www.abgent.com/products/category/protein_modification...
|
 |
E2F6 antibodies: Chromatin and Nuclear Signaling > Transcription ...
E2F6 antibodies. ... E2F6 antibody [TFE61]. IP, WB, ICC/IF. Images · Specific publication references. Mouse monoclonal ...
http://www.abcam.com/index.html?t=73222&pt=1&c=1050&ei=&mu=r...
|
 |
E8655 Monoclonal Anti-E6AP antibody produced in mouse clone E6AP ...
isotype, IgG1. Gene Information, human ... E2F6(1876). rat ... E2f6(313978). mouse ... E2f6(50496). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=E865...
|
 |
TFDP1 antibody, TFDP1 (transcription factor Dp-1) Antibody, Rabbit ...
Part of the E2F6.com-1 complex in G0 phase is composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 YAF2. ...
http://www.genwaybio.com/product_info.php?products_id=43022...
|
 |
T
Monoclonal Anti-E2F6 antibody produced in mouse ~1.0 mg/mL, clone TFE61, purified immunoglobulin, buffered aqueous solution, TFE61 (monoclonal) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
|
 |
Phospho-HP1γ (Ser83) Antibody #2600
In addition to contributing to heterochromatin formation and propagation, HP1 and SUV39H are also found complexed with retinoblastoma (Rb) and E2F6 proteins
...
http://www.cellsignal.com/products/2600.html...
|
 |
Search Bioportfolio and other Life Science Sites for E2F6,
or search for E2F6 on BioPortfolio's antibody search engine.
This page has been viewed 160 times
Recent Search Terms used to find this page: apaf thap | .
Resources from the NCBI used on this page, NCBI's standard disclaimer applies.
|
