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E2F6
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17908821 |
E2F6 binding sites are located within 2 kb of a transcription start site, in both normal and tumor cells |
| 17600109 |
E2F-6 inhibited Apaf-1 upregulation by competing with E2F-1 for promoter binding. It enhanced the clonogenic growth of granulocyte, erythroid, macrophage, & megakaryocyte cells.It may prevent hematopoietic progenitor cell loss during proliferation. |
| 12909625 |
results suggest that E2F6 represses transcription of the brca1, ctip, art27, hp1alpha, and the rbap48 genes and depletion of E2F6 resulted in the recruitment of E2F1 to the target promoters |
| 15536069 |
showed that E2F6, DP1, EPC1, EZH2, and Sin3B co-elute, suggesting the identification of a novel E2F6 complex that exists in vivo in both normal and transformed human cell lines |
| 15081404 |
contains nine exons distributed along 20.4kbp of genomic DNA on chromosome 2 leading to the transcription of six alternatively spliced E2F6 mRNAs that encode four different E2F6 proteins |
| 12004135 |
data suggest that E2F- and Myc-responsive genes are coregulated by E2F6 complex in quiescent cells |
| 16107498 |
the expression of the E2F6 repressor is influenced at the transcriptional level by E2F family members and suggest that interplay among these transcriptional regulators, especially E2F1, may be critical for cell cycle regulation |
| 15574595 |
functions as a repressor of E2F-dependent transcription during S phase |
| 15474455 |
E2F6 does not contain the domains required for modulation of squamous differentiation |
| 17001316 |
PHC3 and E2F6 showed nuclear colocalization in a punctate pattern which was not seen in proliferating cells suggesting that PHC3 may be part of an E2F6-polycomb complex that has been shown to occupy and silence target promoters in G(0) | →View more information from publications. |
Recent Publications on E2F6: |  |
E2f6 and Bmi1 cooperate in axial skeletal development.
Bmi1 is a Polycomb Group protein that functions as a component of Polycomb... | 15th October, 2008
| Center for Cancer Research, Massachusetts Institute of Technology,
| Dev Dyn. 2008 May;237(5):1232-42.
DOI Direct Link |
Human papillomavirus type 16 E7 oncoprotein associates with E2F6.
The papillomavirus life cycle is intimately coupled to the differentiation... | 30th September, 2008
| Department of Medicine, Infectious Diseases Division, The Channing
| J Virol. 2008 Sep;82(17):8695-705. Epub 2008 Jun 25.
DOI Direct Link |
Transcriptional regulation of an evolutionary conserved intergenic region of CDT2-INTS7.
BACKGROUND: In the mammalian genome, a substantial number of gene pairs... | 9th August, 2008
| Department of Life Sciences, Meiji University School of Agriculture,
| PLoS ONE. 2008 Jan 23;3(1):e1484.
DOI Direct Link |
A Conserved E2F6-Binding Element in Murine Meiosis-Specific Gene Promoters.
During gametogenesis, germ cells must undergo meiosis in order to become... | 1st August, 2008
| Department of Pathology, University of Florida College of Medicine,
| Biol Reprod. 2008 Nov;79(5):921-30. Epub 2008 Jul 30.
DOI Direct Link |
E2F6 inhibits cobalt chloride-mimetic hypoxia-induced apoptosis through E2F1.
E2F6, a potent transcriptional repressor, plays important roles in cell... | 20th June, 2008
| Laboratory of Molecular Cardiology, Institute of Health Sciences, Shanghai
| Mol Biol Cell. 2008 Sep;19(9):3691-700. Epub 2008 Jun 18.
DOI Direct Link |
→View more research publications. |
E2F6 results (if any) from reagent suppliers | 
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E2F6 antibody [TFE61] (ab11952) datasheet | Abcam
Mouse monoclonal [TFE61] to E2F6. The E2F6 gene encodes a member of the E2F transcription factor protein family. E2F family members play a crucial role in
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http://www.abcam.com/index.html?datasheet=11952...
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WH0001876M1 Monoclonal Anti E2F6 antibody produced in mouse clone ...
WH0001876M1 Monoclonal Anti-E2F6 antibody produced in mouse clone 2B6-G9, purified immunoglobulin, buffered aqueous solution.
http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIG...
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E2F6 antibodies | Abcam
E2F6 antibodies. ... Image Abreview Publication. ab53061 · E2F6 antibody. WB, ELISA. Images. Rabbit polyclonal. Reacts with:. Hu, Ms ...
http://www.abcam.com/index.html?t=73222&pt=1&c=3423...
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E2F6 E2F transcription factor 6
E2F6; E2F-6; MGC111545. Other Designations. E2F transcription factor 6, isoform 1 ... WH0001876M1, Monoclonal Anti-E2F6 antibody produced in mouse clone ...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...
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Antibody Products - IgG Polyclonal Antibodies - GenWay
E2F transcription factor 6 isoform 4; E2F6 splice variant f, IgG Polyclonal ... 18-003-42161, E2F6 (E2F transcription factor 6) - E2F6; E2F-6 ...
http://www.genwaybio.com/all_polyclonal_antibodies.php?fl=E...
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E2f6 E2F transcription factor 6
transcriptional repressor E2F6. Refseq ID(s). NM_033270. Accession No.(s) ... E2f6(Rat). Function(s). DNA binding; transcription factor. Replaces Gene ID(s)
...
http://www.sigmaaldrich.com/catalog/search/SIRNASearchGeneDe...
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STAG3 (D-20) Antibody sc-20341
Silencing of the Meiotic Genes SMC1{beta} and STAG3 in Somatic Cells by E2F6. J. Biol. Chem. 280: 41380-41386. View PubMed Entry ...
http://www.scbt.com/datasheet-20341-stag3-d-20-antibody.html...
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Gene Regulation and Expression
E1532, Monoclonal Anti-E2F6 antibody produced in mouse ~1.0 mg/mL, clone TFE61, purified immunoglobulin, buffered aqueous solution New ...
http://www.sigmaaldrich.com/life-science/cell-biology/cell-b...
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HP1γ Antibody #2619
In addition to contributing to heterochromatin formation and propagation, HP1 and SUV39H are also found complexed with retinoblastoma (Rb) and E2F6 proteins
...
http://www.cellsignal.com/products/2619.html...
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Antibodies to E1,E2,E3 Ligase
purified immunoglobulin, human ... E2F6(1876) mouse ... E2f6(50496) rat ... E2f6 (313978), human, monkey, rat, mouse, ARR, ELISA (i), ICC, IP, WB ...
http://www.sigmaaldrich.com/catalog/search/TablePage/1928289...
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