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E4F1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17557114 |
LANP and ATAXN1 interact in E4F-mediated transcriptional repression. |
| 14729613 |
Specific inactivation of RASSF1A by short interfering RNA disrupts binding of RASSF1A to p120(E4F) in tumor cells. |
| 15579445 |
E4F1 function involves ER alpha-mediated inhibition of VSMC proliferation and estrogen-related atheroprotection of human |
| 17110336 |
E4F1 is a key posttranslational regulator of p53, which modulates its effector functions involved in alternative cell fates: growth arrest or apoptosis. |
| 12446718 |
association of p120E4F with p14ARF enhances cell cycle inhibition |
| 16652157 |
findings show that full-length E4F1 protein but not its E1A-activated & truncated form interacts in vitro & in vivo with FHL2; this E4F1-FHL2 association occurs in the nuclear compartment & inhibits the capacity of E4F1 to block cell proliferation |
Recent Publications on E4F1: |  |
The role of LANP and ataxin 1 in E4F-mediated transcriptional repression.
The leucine-rich acidic nuclear protein (LANP) belongs to the INHAT family... | 24th October, 2007
| Davee Department of Neurology, Northwestern University Feinberg School of
| EMBO Rep. 2007 Jul;8(7):671-7. Epub 2007 Jun 8.
DOI Direct Link |
E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation.
p53 is regulated by multiple posttranslational modifications, including... | 23rd December, 2006
| Institut de Genetique Moleculaire CNRS-UMII UMR5535, IFR122, Montpellier
| Cell. 2006 Nov 17;127(4):775-88.
DOI Direct Link |
A new function for p53 ubiquitination.
The amount of p53 protein in a cell is normally limited by... | 23rd December, 2006
| Burnham Institute for Medical Research, La Jolla, CA 92130, USA.
| Cell. 2006 Nov 17;127(4):675-7.
DOI Direct Link |
The LIM-only protein FHL2 is a negative regulator of E4F1.
The E1A-targeted transcription factor E4F1 is a key player in the control... | 30th September, 2006
| Institut de Genetique Moleculaire, UMR 5535/IFR122, CNRS, Montpellier,
| Oncogene. 2006 Sep 7;25(40):5475-84. Epub 2006 May 1.
DOI Direct Link |
E4F1: a novel candidate factor for mediating BMI1 function in primitive hematopoietic cells.
The Polycomb group gene Bmi1 is essential for the proliferation of neural... | 26th September, 2006
| Laboratory of Molecular Genetics of Hematopoietic Stem Cells, Institut de
| Genes Dev. 2006 Aug 1;20(15):2110-20.
DOI Direct Link |
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