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EBF1


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Symbol:EBF1
Name(s):early B-cell factor 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:COE1, EBF, FLJ39389, FLJ41763, O/E-1, OLF1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16255771 Observational study of gene-disease association. (HuGE Navigator)
16106032 EBF-1 and PPARgamma2 induce adipocyte differentiation with comparable kinetics and efficiency.
17101802 The regulation of Ebf1 via distinct promoters allows for the generation of several feedback loops and the coordination of multiple determinants of B lymphopoiesis in a regulatory network.
16255771 Two genetic markers within the EBF1 gene have been found associated with multiple sclerosis, indicative either of their causative role or that of some other polymorphism in linkage disequilibrium with them.
11994467 Three independent binding sites for EBF in the surrogate light chain VpreB promoter are important for the full function of the promoter and its collaborative activation by EBF and E47 in a preB cell line.
15920012 data suggest that Notch signaling may affect B-versus T-lineage commitment by the targeting of both EBF and E2A

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCREBBPearly B-cell factor--Pubmed
HPRDCREB binding proteinearly B-cell factor--Pubmed
HPRDEarly B cell factorOLF-1/EBF associated zinc finger protein--Pubmed
HPRDearly B-cell factorOAZ--Pubmed
HPRDearly B-cell factorzinc finger protein 521--Pubmed
HPRDearly B-cell factorearly B-cell factor--Pubmed

Recent Publications on EBF1:

Pubmed Logo
c-Myb is required for pro-B cell differentiation.
The c-Myb transcription factor is required for normal adult hematopoiesis....
22nd October, 2009
Department of Microbiology, University of Virginia Health System, J Immunol. 2009 Nov 1;183(9):5582-92.
DOI Direct Link
Genoarchitectonic profile of developing nuclear groups in the chicken pretectum.
Earlier results on molecularly coded progenitor domains in the chicken...
1st October, 2009
Department of Human Anatomy and Psychobiology, University of Murcia, J Comp Neurol. 2009 Dec 1;517(4):405-51.
DOI Direct Link
Isomer-specific effects of CLA on gene expression in human adipose tissue depending on PPARgamma2 P12A polymorphism: a double blind, randomized, controlled cross-over study.
BACKGROUND: Peroxisome proliferator-activated receptor (PPAR)gamma is a...
20th August, 2009
Department of Physiology and Biochemistry of Nutrition, Max Lipids Health Dis. 2009 Aug 18;8:35.
DOI Direct Link
Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5.
Transcriptionally silent genes are maintained in inaccessible chromatin....
28th July, 2009
Program in Molecular Biology, University of Colorado at Denver Health Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11258-63. Epub 2009 Jun 19.
DOI Direct Link
Ventral mesencephalon-enriched genes that regulate the development of dopaminergic neurons in vivo.
Mesodiencephalic dopaminergic (mDA) neurons are critical for movement...
23rd May, 2009
Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell J Neurosci. 2009 Apr 22;29(16):5170-82.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7585632 Compositions and methods for the detection of a nucleic acid using a cleavage reaction
7534568 Methods for detection of a target nucleic acid by forming a cleavage structure with a cleavage resistant probe
7482121 Methods for detection of a target nucleic acid by capture
7468251 Compositions for detection of A target nucleic acid sequence
7460034 Method and device for code generation in the transmission of data via a communications system

View more patents.

EBF1 results (if any) from reagent suppliers

Google CSE Logo
EBF1 antibody (ab31735) | Abcam
Rabbit polyclonal to EBF1. EBF1 belongs to the COE family. It contains 1 IPT/TIG domain. EBF1 is a transcriptional activator which recognizes variations of ...
http://www.abcam.com/COE1-EBF-antibody-ab31735.html...

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EBF1 (S-22) Antibody sc-133527
rabbit polyclonal IgG, 50 µg/0.5 ml; recommended for detection of EBF1 of ... Western blot analysis of EBF1 expression in human fetal brain tissue extract.
...
http://www.scbt.com/datasheet-133527-ebf1-s-22-antibody.html...

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EBF1 antibodies: Chromatin and Nuclear Signaling > Transcription ...
EBF1 antibodies. ... EBF1 antibody. WB, ELISA. Images. Rabbit polyclonal. Reacts with: Hu, Ms, Rat, Ce, Dm. ab85689 · EBF1 antibody ...
http://www.abcam.com/index.html?t=272119&pt=1&c=3579&ei=&mu=...

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EBF1 siRNA (m) sc-143277
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: EBF1 ...
http://www.scbt.com/de/datasheet-143277-ebf1-sirna-m.html...

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EBF1 antibodies: Stem Cells > Hematopoietic Progenitors > Surface ...
EBF1 antibodies. ... EBF1 antibodies. Code. Name. Applications (see key) & Reactivity (see key). Image Abreview Publication. ab31735 · EBF1 antibody ...
http://www.abcam.com/index.html?t=272119&pt=1&c=3568&ei=&mu=...

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EBF Antibody / EBF Antibodies
EBF1 (S-22) Antibody, sc-133527, rabbit IgG, N/A, WB, IP, ELISA, m, r, h ... EBF1 shRNA (h) Lentiviral Particles: sc-106965-V. EBF1 siRNA (m): sc-143277 ...
http://www.scbt.com/table-ebf.html...

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ORDERING INFORMATION
26 Sep 2008 ... EBF-1 (Early B cell Factor 1; also OLF1 and COE1) is a 65 - 70 kDa ... studied in B cells where IL-7 acts to promote EBF-1 in pre-proB cells ...
http://www.rndsystems.com/pdf/AF5165.pdf...

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