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ECM1


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Gene DB Home
Symbol:ECM1
Name(s):extracellular matrix protein 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17927570 This article provides an update on the molecular pathology of lipoid proteinosis, including the addition of 15 new mutations in ECM1 to the mutation database [review]
17721643 We report here mutation analysis of the ECM1 gene in a Chinese family with lipoid proteinosis.
16512877 it is reported here that ECM1 interacts with MMP9 and that such interactions diminish the proteolytic activity of MMP9
16274456 Frther emphasizes the role of ECM-1 in lipoid proteinosis and highlights unresolved genotype-phenotype correlation in this disease.
14550953 These results indicate that ECM1 tends to be preferentially expressed by metastatic epithelial tumors.
12603844 Extracellular matrix protein 1 gene (ECM1) mutations in lipoid proteinosis and genotype-phenotype correlation. Seven new homozygous nonsense or frameshift mutations. Exons 6 and 7 most common sites for ECM1 mutations.

Recent Publications on ECM1:

Pubmed Logo
Genetic Analysis in A Dutch Study Sample Identifies More Ulcerative Colitis Susceptibility Loci and Shows Their Additive Role in Disease Risk.
OBJECTIVES:Genetic susceptibility is known to make a major contribution to...
29th October, 2009
[1] Department of Gastroenterology and Hepatology, University Medical Am J Gastroenterol. 2009 Oct 27.
DOI Direct Link
Genetics of inflammatory bowel disease: implications for disease pathogenesis and natural history.
Epidemiological data, detailed molecular studies and recent genome-wide...
13th October, 2009
Gastrointestinal Unit, Molecular Medicine Centre, University of Edinburgh, Expert Rev Gastroenterol Hepatol. 2009 Oct;3(5):513-34.
DOI Direct Link
Extracellular matrix 1 (ECM1) expression is a novel prognostic marker for poor long-term survival in breast cancer: a Hospital-based Cohort Study in Iowa.
INTRODUCTION: Previous work in a small, unselected series showed that up...
30th September, 2009
Department of Surgery, University of Iowa, Iowa City, IA, USA. Ann Surg Oncol. 2009 Aug;16(8):2280-7. Epub 2009 Jun 12.
DOI Direct Link
Novel human pathological mutations. Gene symbol: ECM1. Disease: Lipoid Proteinosis.
SUMMARY: Lipoid proteinosis is a rare genodermatosis characterized by...
9th September, 2009
IBGE, Institute of Biomedical and Genetic Engineering, Islamabad, Hum Genet. 2009 Aug;126(2):336.
Amygdalae and Striatum Calcification in Lipoid Proteinosis.
SUMMARY: Lipoid proteinosis is a rare genodermatosis characterized by...
22nd August, 2009
Departamento de Radiologia do Hospital Universitario da Universidade de AJNR Am J Neuroradiol. 2009 Aug 20.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
4032895 Electronic data processing computer
6610480 Treatment and diagnosis of cardiac hypertrophy
6610829 Human extracellular matrix-1
6673597 Growth stimulation of biological cells and tissue by electromagnetic fields and uses thereof
6673623 Methods and compositions that control lipid production

View more patents.

ECM1 results (if any) from reagent suppliers

Google CSE Logo
ECM Antibody / ECM Antibodies
ECM1 (E-18) Antibody, sc-65082, goat IgG, Internal (r), WB, IF, ELISA, rat ... ECM1 (N-17) Antibody, sc-65086, goat IgG, N-terminus (h), WB, IP, IF, ELISA ...
http://www.scbt.com/table-ecm.html...

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Immunohistochemistry : ECM-1 - R&D Systems
This antibody specifically recognizes human ECM-1. This antibody has not yet been tested in other species. This antibody can be used for ...
http://www.rndsystems.com/ihc_molecule_images.aspx?m=3424...

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ECM1 siRNA (m) sc-62256
Click here for details. suitable control antibody: ECM1 (M-18): sc-65085; sqRT- PCR Primer also available: ECM1 (m)-PR: sc-62256, 20 µl ...
http://www.scbt.com/ko/datasheet-62256-ecm1-sirna-m.html...

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ORDERING INFORMATION
28 May 2008 ... Mature mouse ECM-1 shares 67% and 90% aa identity with ... specific IgG was purified by mouse ECM-1 affinity chromatography. Formulation ...
http://www.rndsystems.com/pdf/AF4428.pdf...

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ECM1 siRNA (h) sc-62255
Click here for details. suitable control antibody: ECM1 (N-17) : sc-65086; sqRT- PCR Primer also available: ECM1 (h)-PR: sc-62255, 20 µl ...
http://www.scbt.com/ko/datasheet-62255-ecm1-sirna-h.html...

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IRGM Antibody (NT) gamma-interferon-induced GTP-binding protein
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat. Genet. 2008; 40:710-2. ...
http://www.prosci-inc.com/shop/catalog1/IRGM-Antibody-p-6656...

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ECM1 (E-18) Antibody sc-65082
goat polyclonal IgG, 200µg/ml; epitope mapping within an internal region of ECM1 of rat origin; recommended for detection of Extracellular Matrix Protein 1 ...
http://www.scbt.com/ko/datasheet-65082-ecm1-e-18-antibody.ht...

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