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EDA


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Gene DB Home
Symbol:EDA
Name(s):ectodysplasin A
Type:protein-coding
Organism:Homo sapiens
Synonyms:ED1, ED1-A1, ED1-A2, EDA1, EDA2, HED, XHED, XLHED
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12930312 identified ED1 mutations including three novel mutations by sequencing genomic DNAs from eight unrelated Japanese X-linked hypohidrotic ectodermal dysplasia families
12920369 The ED1 gene was identified as a responsive gene for X-LINKED HYPOHIDROTIC ECTODERMAL DYSPLASIA.
17102627 EDA signaling has a role in skin appendage development [review]
12673367 The structure of the EDA1 gene in a patient with anhidrotic ectodermal dysplasia
16423472 isoforms of EDA-A5 and A5',activated NF-kappaB through receptors EDAR and XEDAR
17256800 An amino acid substitution in ectodysplasin A is associated with X-linked dominant incisor hypodontia.
17478381 Report of a novel insertion mutation in EDA1 gene in a Pakistani family with x-linked hypohidrotic ectodermal dysplasia.
15663448 point mutation (G1149A) in exon 8 changes codon 291 from glycine to arginine causing X-linked hypohidrotic ectodermal dysplasia
12682853 Identified ED1 mutations including one novel mutation in the 5' splice site following exon 8 (IVS8+5delG) and another missense mutation (A959G; Y320C), which has been reported previously.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDectodysplasin A isoform EDA-A1Homo sapiens X-linked ectodermal dysplasia receptor long isoform mRNA, complete cds, alternatively spliced--Pubmed
HPRDectodysplasin A isoform EDA-A1Homo sapiens X-linked ectodermal dysplasia receptor long isoform mRNA, complete cds, alternatively spliced--Pubmed
HPRDectodysplasin A isoform EDA-A1ectodysplasin A receptor--Pubmed
HPRDectodysplasin A isoform EDA-A1ectodysplasin A receptor--Pubmed

Recent Publications on EDA:

Pubmed Logo
DARPin-Assisted Crystallography of the CC2-LZ Domain of NEMO Reveals a Coupling between Dimerization and Ubiquitin Binding.
NEMO is an integral part of the IkappaB kinase complex and serves as a...
27th October, 2009
Unite de Biochimie Structurale et Cellulaire, Institut Pasteur, CNRS, URA J Mol Biol. 2009 Oct 23.
DOI Direct Link
S-layer templated bioinspired synthesis of silica.
The current understanding of the molecular mechanisms involved in the...
27th October, 2009
Center for NanoBiotechnology, University of Natural Resources and Applied Colloids Surf B Biointerfaces. 2009 Oct 2.
DOI Direct Link
Effect-directed analysis of contaminated sediments with partition-based dosing using green algae cell multiplication inhibition.
Effect-directed analysis (EDA) has been frequently and successfully used...
24th October, 2009
Department of Effect-Directed Analysis, UFZ - Helmholtz Centre for Environ Sci Technol. 2009 Oct 1;43(19):7343-9.
Automatic EEG spike detection.
Since the 1970s advances in science and technology during each succeeding...
24th October, 2009
BrainVue Systems, Philadelphia, Pennsylvania, PA 19129, USA. Clin EEG Neurosci. 2009 Oct;40(4):262-70.
Brain activation patterns underlying fast habituation to painful laser stimuli.
A painful experience is modified by processes like...
17th October, 2009
Neuropsychiatric Research Laboratory, Department of Psychiatry, Int J Psychophysiol. 2009 Oct 12.
DOI Direct Link

View more research publications.

Press Releases on EDA:

BioPortfolio Logo
Oticon Tapes Out Innovative Hearing-Aid DSP Using Synopsys IC Compiler 2nd June, 2008 Synopsys, Inc.

MOUNTAIN VIEW, Calif., June 2 /PRNewswire-FirstCall/ -- Synopsys, Inc. (Nasdaq: SNPS), a world leader in software and IP for semiconductor design and manufacturing, today announced that Oticon

BioNews Results for EDA

: RSS Logo
BioPortfolio Logo
Working together to design robust silicon chips
Research & Development:  Nov 13 2009 2:53PM Matching: eda
Researchers Study Salivary Gland Development
Dentistry Today:  Nov 2 2009 9:54PM Matching: eda
AWR Receives Three U.S. Government Small Business Innovation Research Program (SBIR) Grants
Genetic Engineering News:  Oct 19 2009 1:25PM Matching: eda
Semiconductor Industry Leader Kenneth Venner Provides Guidance to Promote Adoption of High-Performance Memory Appliances in Corporate Data Centers
Research & Development:  Oct 6 2009 12:47PM Matching: eda
IMEC Launches Program to Help Companies Developing Emerging IC Process Technologies
Research & Development:  Oct 6 2009 7:53AM Matching: eda
Promote your company here: BioNewsCast - Press Release Distribution

View more news.

Clinical Trials:

Clinical Trials Logo
Acupuncture as Pain Relief and Relaxation During Childbirth

Patents:

Patents logo
US Patent No.Title
7598294 3,4-methylenedioxy-substituted chalcones as therapeutic agents
7603329 Data set modification using training algorithm that grows the data set
7603562 System and method for reducing memory requirements of firmware
7603644 Integrated circuit routing and compaction
7603656 Methods and systems for modeling concurrent behavior

View more patents.

EDA results (if any) from reagent suppliers

Google CSE Logo
EDA (T-21) Antibody sc-130746
rabbit polyclonal IgG, 100µg/ml; recommended for detection of EDA of human ... EDA (T-21): sc-130746. Western blot analysis of EDA expression in HeLa whole ...
http://www.scbt.com/datasheet-130746-eda-t-21-antibody.html...

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EDA antibodies: Developmental Biology > Lineage specification ...
EDA antibodies. ... EDA antibody [Renzo-1]. IHC-P, WB, ELISA, ICC/IF, IP. Specific publication references. Mouse monoclonal ...
http://www.abcam.com/index.html?t=224508&pt=1&c=4604&ei=&mu=...

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EDA Antibody / EDA Antibodies
EDA Antibody / EDA Antibodies. ... EDA specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-eda.html...

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ORDERING INFORMATION
14 May 2007 ... The products of the Ectodysplasin A gene (EDA, also called Tabby) are type II ... amino acids in the extracellular domain of EDA-A2. ...
http://www.rndsystems.com/pdf/MAB9222.pdf...

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EDA (4867-5) Antibody sc-73920
mouse monoclonal IgG1, 100µg/ml; raised against the extracellular domain of EDA- A2 of human origin; recommended for detection of EDA-A2, also designated ...
http://www.scbt.com/datasheet-73920-eda-4867-5-antibody.html...

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human EDA DuoSet
human Ectodysplasin (EDA). DuoSets are designed ... biotinylated mouse anti- human EDA when reconstituted ... 70 ng/mL of recombinant human EDA-A2 when ...
http://www.rndsystems.com/pdf/DY922.pdf...

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XEDAR Antibody Ectodysplatin-A2 receptor
Cells transfected with XEDAR and treated with EDA-A2 cause the assembly of a ... The EDA-A2-induced apoptosis is dependent on caspase-9 activation, ...
http://www.prosci-inc.com/shop/catalog1/XEDAR-Antibody-p-637...

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