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ABCA1

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Symbol:	ABCA1
Name(s):	ATP-binding cassette, sub-family A (ABC1), member 1
Type:	protein-coding
Organism:	Homo sapiens
Synonyms:	ABC-1, ABC1, CERP, FLJ14958, HDLDT1, MGC164864, MGC165011, TGD
Links:	Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications
Publication Link	Summary of findings
18097620	Observational study of gene-disease association. (HuGE Navigator)
18199144	Observational study of gene-disease association. (HuGE Navigator)
18215356	Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18219093	Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18239666	Observational study of gene-disease association. (HuGE Navigator)
18354102	Observational study of gene-disease association. (HuGE Navigator)
17481640	ABCA1 expression in human leukocytes and muscle is associated with physical activity and alcohol consumption, respectively
17550732	Observational study of gene-disease association. (HuGE Navigator)
17553166	Observational study of gene-disease association. (HuGE Navigator)
17608096	Observational study of gene-disease association. (HuGE Navigator)
→View more information from publications.

Interacting gene products
Interaction Type	Gene 1	Gene 2	Interaction description	Complex	Publication Link
HPRD	ABC1	basic beta 2 syntrophin	-	-	Pubmed
HPRD	ATP-binding cassette, sub-family A member 1	Syntrophin beta 2	-	-	Pubmed
HPRD	ATP-binding cassette, sub-family A member 1	Fas-associated via death domain	-	-	Pubmed
HPRD	ATP-binding cassette, sub-family A member 1	Fas-associated via death domain	-	-	Pubmed

Recent Publications on ABCA1:
Exendin-4 regulates pancreatic ABCA1 transcription via CaMKK/CaMKIV pathway. ABSTRACT OBJECTIVES: ATP-binding cassette transporter A1 (ABCA1) in...	31st October, 2009	Division of Endocrinology and Metabolism, Department of Internal Medicine,	J Cell Mol Med. 2009 Oct 29. DOI Direct Link
Alterations in cholesterol regulation contribute to the production of intratumoral androgens during progression to castration-resistant prostate cancer in a mouse xenograft model. BACKGROUND: Emerging evidence suggests that androgens and the androgen...	30th October, 2009	Faculty of Pharmaceutical Sciences, University of British Columbia,	Prostate. 2009 Oct 28. DOI Direct Link
Changes in Cholesterol Biosynthetic and Transport Pathways after Excitotoxicity. The present study was carried out to elucidate changes in the gene...	29th October, 2009	Department of Anatomy, National University of Singapore, Singapore 119260.	J Neurochem. 2009 Oct 24. DOI Direct Link
Liver X receptor agonist inhibits proliferation of ovarian carcinoma cells stimulated by oxidized low density lipoprotein. OBJECTIVES: We previously observed an association between ovarian cancer...	27th October, 2009	Women's Cancer Research Institute and Division of Gynecologic Oncology,	Gynecol Oncol. 2009 Oct 23. DOI Direct Link
4-(3-Aryloxyaryl)quinoline alcohols are liver X receptor agonists. A series of 4-(3-aryloxyaryl)quinolines with alcohol substituents on the...	27th October, 2009	Chemical Sciences, Wyeth Pharmaceuticals, 500 Arcola Road, Collegeville,	Bioorg Med Chem. 2009 Oct 4. DOI Direct Link
→View more research publications.

Press Releases on ABCA1:
RVX-208 Data Demonstrates Increase in Functional HDL Particles	10th November, 2008	Resverlogix Corp.	Prebeta-HDL generation and improved HDL functionality are distinguishing factors TSX Exchange Symbol: RVX NEW ORLEANS, LA, Nov. 10 /PRNewswire-FirstCall/ -

BioNews Results for ABCA1 :
Statins may have different brain effects	The Money Times: Nov 3 2009 9:18AM Matching: abca1
Statins May Have Different Brain Effects	Post Chronicle: Nov 2 2009 7:25PM Matching: abca1
Medical News: Statins Show Dramatic Drug And Cell Dependent Effects In The Brain	Medical News Today: Oct 29 2009 3:47PM Matching: abca1
Long-term effects of statin therapy could lead to transient or permanent cognitive impairment	News-Medical.Net: Oct 29 2009 8:52AM Matching: abca1
Statins show dramatic drug and cell dependent effects in the brain	Genetic Engineering News: Oct 28 2009 3:55PM Matching: abca1
Promote your company here: BioNewsCast - Press Release Distribution	→View more news.

Clinical Trials:
The Effect of Alcohol on ABCA1 Expression and Lipid Metabolism

Patents:
US Patent No.	Title
7285395	Stearoyl-CoA desaturase 4 gene
7375191	Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
7378396	Therapeutic agents and methods for cardiovascular disease
7387895	Monoclonal antibody specific for PPAR gamma, hydridoma cell line producing the same, and method for detecting regulator related to diseases, including inflammation, cancer and metabolic diseases, using the same
7393826	Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
→View more patents.

ABCA1 results (if any) from reagent suppliers

ABCA1 antibody [AB.H10] (ab18180) \| Abcam H10] to ABCA1. This membrane-associated protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various ... http://www.abcam.com/ABCA1-antibody-AB-H10-ab18180.html...
ABCA1 antibody, ABCA1 Antibody, Mouse Monoclonal Antibody Buy quality mouse ABCA1 antibody (interacts with human mouse and chicken), ... Mouse Anti ABCA1; ATP-binding cassette transporter 1; ATP-binding cassette 1 ... http://www.genwaybio.com/product_info.php?products_id=80098...
ABCA1 antibody (ab14146) \| Abcam Rabbit polyclonal to ABCA1. This membrane-associated protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. http://www.abcam.com/ABCA1-antibody-ab14146.html...
Anti-ABCA1 Monoclonal Antibody Monoclonal Antibody against ABCA1 for use in Western Blot. http://www.bioreagents.com/products/productDetails/productDe...
ABCA1 Monoclonal Antibody ATP-Binding Cassette, Sub-Family A ABCA1 monoclonal antibody can be used for detection of ABCA1 by WB, ELISA, IHC- parafin (minimum working concentration: 10 μg/ml maximum working ... http://www.prosci-inc.com/shop/catalog1/ABCA1-Monoclonal-Ant...
Anti-ABCA1 Monoclonal Antibody Monoclonal Antibody against ABCA1 for use in Flow Cytometry. http://www.bioreagents.com/products/productDetails/productDe...
ABC Antibody / ABC Antibodies ABCA1 shRNA Plasmid (h): sc-61901-SH. ABCA1 shRNA (h) Lentiviral Particles: sc- 61901-V. ABCA1 ... ABCA1 shRNA Plasmid (m): sc-61902-SH. ABCA1 shRNA (m) ... http://www.scbt.com/table-abc.html...

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Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

ABCA1

Gene Information from Publications

Interacting gene products

Recent Publications on ABCA1:

Press Releases on ABCA1:

BioNews Results for ABCA1

Clinical Trials:

Patents:

ABCA1 results (if any) from reagent suppliers