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EDN1


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Gene DB Home
Symbol:EDN1
Name(s):endothelin 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:ET1, HDLCQ7
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18288492 Observational study of gene-disease association. (HuGE Navigator)
17960156 Polymorphisms in EDN1 are associated with asthma in two populations.
18023202 IL-8 induces imbalances between nitric oxide and endothelin-1, and also between plasminogen activator inhibitor-1 and tissue-type plasminogen activator in cultured endothelial cells
18005077 Concentric contraction is associated with ET-1 production and a greater increase in blood pressure compared with eccentric contraction.
18025413 ET-1 is released from human adipose tissue and links fat accumulation to insulin resistance
18260253 endothelin-1 could be involved in the pathogenesis of seasonal allergic rhinitis.
15198485 Observational study of gene-disease association. (HuGE Navigator)
15240857 Observational study of gene-disease association. (HuGE Navigator)
15369130 Observational study of gene-disease association. (HuGE Navigator)
15505112 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDadrenomedullinendothelin 1--Pubmed
HPRDadrenomedullinendothelin 1--Pubmed
HPRDendothelin 1endothelin receptor type B isoform 1 precursor--Pubmed
HPRDendothelin 1endothelin receptor type B isoform 1 precursor--Pubmed
HPRDendothelin 1endothelin receptor type A--Pubmed
HPRDendothelin 1endothelin receptor type A--Pubmed
HPRDendothelin 1natriuretic peptide precursor C--Pubmed
HPRDendothelin 1natriuretic peptide precursor C--Pubmed

Recent Publications on EDN1:

Pubmed Logo
Association study between keratinocyte-derived growth factor gene polymorphisms and susceptibility to vitiligo vulgaris in a Taiwanese population: potential involvement of stem cell factor.
BACKGROUND: Vitiligo vulgaris is a depigmentary disorder resulting from...
3rd November, 2009
Department of Dermatology, Kaohsiung Medical University Hospital, Br J Dermatol. 2009 Jun;160(6):1180-7. Epub 2009 Mar 13.
DOI Direct Link
Amphetamine and environmentally induced hyperthermia differentially alter the expression of genes regulating vascular tone and angiogenesis in the meninges and associated vasculature.
An amphetamine (AMPH) regimen that does not produce a prominent...
27th October, 2009
US Food and Drug Administration, National Center for Toxicological Synapse. 2009 Oct;63(10):881-94.
DOI Direct Link
Endothelin-1, endothelin converting enzyme-1 and endothelin receptors in the porcine corpus luteum.
Porcine corpora lutea (CL) fail to show a luteolytic response to...
29th September, 2009
Department of Molecular Biomedical Sciences, College of Veterinary Domest Anim Endocrinol. 2009 Sep 18.
DOI Direct Link
Maternal EDN1 G5665T polymorphism influences circulating endothelin-1 levels and plays a role in determination of preeclampsia phenotype.
OBJECTIVE: Preeclampsia, a pregnancy-specific syndrome characterized by...
5th September, 2009
aDepartment of Nephrology, India bDepartment of Obstetrics & Gynaecology, J Hypertens. 2009 Aug 28.
DOI Direct Link
Progesterone Receptor-Induced Gene Expression in Primary Mouse Granulosa Cell Cultures.
The progesterone receptor (PGR) is induced by LH in granulosa cells of...
4th September, 2009
Biol Reprod. 2009 Sep 2.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
The Effects of Diesel Exhaust Inhalation on Vascular Function - the Role of Endothelin

Patents:

Patents logo
US Patent No.Title
7611841 Method for detecting methylation of promoter using restriction enzyme and DNA chip
6964850 Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
6960439 Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles
6936417 Gene expression in bladder tumors
6905827 Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases

View more patents.

EDN1 results (if any) from reagent suppliers

Google CSE Logo
Endothelin 1 antibody, Endothelin 1 [1.B.759] Antibody, Mouse ...
B.759] to Endothelin 1; 1906; EDN1; 131240; P05305; ET1;; Endothelin-1, EDN1_HUMAN. [ N/A NP_001946.3 P05305 ]. ( GenWay 20-272-191636 online datasheet
)
http://www.genwaybio.com/product_info.php?products_id=191636...

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Antibodies to Neuropeptides
human ... EDN1(1906), pig, human, rat, ELISA (i), RIA, pricing ... rat ... Edn1( 24323), human, pig, rat, ARR, DB, ELISA (i), IHC (f), RIA, pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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HIV1 tat antibody (ab14029) | Abcam
Upon stimulation with EDN1, it is exported from the nucleus to the perinuclear region. Research areas. Microbiology >> Organism >> Virus >> RNA Virus ...
http://www.abcam.com/HIV1-tat-antibody-ab14029.html...

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E0771 Monoclonal Anti-Endothelin antibody produced in mouse clone ...
radioimmunoassay: 1:20000. isotype, IgG2a. Gene Information, human ... EDN1(1906 ). rat ... Edn1(24323). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=E077...

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ET-1 (1C10) Antibody sc-57116
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, EDN1, 1906, 6p24.1, NM_001955 ...
http://www.scbt.com/datasheet-57116-et-1-1c10-antibody.html...

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E166 Monoclonal Anti-Endothelin-1 antibody produced in mouse clone ...
immunoprecipitation: suitable. radioimmunoassay: 1:25000. isotype, IgG1. Gene Information, human ... EDN1(1906). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=E166...

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Endothelin Antibody / Endothelin Antibodies
제품명, 카탈로그 번호, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. ET-1 (1C10) Antibody, sc-57116, mouse IgG1, N/A, ELISA, human ...
http://www.scbt.com/ko/table-endothelin.html...

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