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EDN2


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Gene DB Home
Symbol:EDN2
Name(s):endothelin 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:ET2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18037749 Observational study of gene-disease association. (HuGE Navigator)
18037749 The EDN2 A985 allele, which is considered to be protective in cardiovascular disease, may be a risk factor for atrial fibrillation in patients with hypertrophic cardiomyopathy.
12516960 Endothelin-2 is a hypoxia-induced autocrine survival factor for breast tumor cells
12207323 Endothelin-2 is a macrophage chemoattractant. ET-2 expression by tumors may modulate the behavior of macrophages such that activated cells accumulate in areas of hypoxia.

Recent Publications on EDN2:

Pubmed Logo
Endogenous leukemia inhibitory factor protects photoreceptor cells against light-induced degeneration.
PURPOSE: Expression of leukemia inhibitory factor (LIF) by a subset of...
29th October, 2009
Department of Ophthalmology, Laboratory for Retinal Cell Biology, Zurich Mol Vis. 2009 Aug 18;15:1631-7.
Frequent loss of endothelin-3 (EDN3) expression due to epigenetic inactivation in human breast cancer.
INTRODUCTION: Endothelin (EDN) signalling plays a crucial role in cell...
17th June, 2009
Molecular Oncology Group, Institute of Pathology, University Hospital of Breast Cancer Res. 2009;11(3):R34. Epub 2009 Jun 15.
DOI Direct Link
A whole genome association analysis identifies loci associated with Mycobacterium avium subsp. paratuberculosis infection status in US holstein cattle.
The purpose of this study was to identify loci associated with...
9th May, 2009
Department of Animal Sciences, Washington State University, Pullman, WA Anim Genet. 2009 Oct;40(5):655-62. Epub 2009 Apr 24.
DOI Direct Link
The endothelin system: evolution of vertebrate-specific ligand-receptor interactions by three rounds of genome duplication.
Morphological innovations like the acquisition of the neural crest as well...
14th April, 2009
University of Wurzburg, Biozentrum, Physiological Chemistry I, Germany. Mol Biol Evol. 2009 Apr;26(4):783-99. Epub 2009 Jan 27.
DOI Direct Link
Leukemia inhibitory factor extends the lifespan of injured photoreceptors in vivo.
Survival and death of photoreceptors in degenerative diseases of the...
13th January, 2009
Laboratory for Retinal Cell Biology, Department of Ophthalmology, Center J Neurosci. 2008 Dec 17;28(51):13765-74.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7588767 Microorganisms for therapy
7482124 Method of identifying a PPARgamma-agonist compound having a decreased likelihood of inducing dose-dependent peripheral edema
7259997 Flash memory device with reduced access time
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector

View more patents.

EDN2 results (if any) from reagent suppliers

Google CSE Logo
ET-2 (C-8) Antibody sc-21627
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, EDN2, 1907, 1p34.2, NM_001956 ...
http://www.scbt.com/datasheet-21627-et-2-c-8-antibody.html...

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Group II introns as controllable gene targeting vectors for ...
world, Edn. 2. (eds Gesteland, R.F., Cech, T.R. & Atkins, J.F.) 451–484 (Cold .... Edn. 2. (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY; ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/General_...

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Endothelin Antibody / Endothelin Antibodies
제품명, 카탈로그 번호, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. ET-1 (1C10) Antibody, sc-57116, mouse IgG1, N/A, ELISA, human ...
http://www.scbt.com/ko/table-endothelin.html...

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ET-2 siRNA (m) sc-144951
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Mouse, Edn2, 13615, 4 D2.2, P22389 ...
http://www.scbt.com/ko/datasheet-144951-et-2-sirna-m.html...

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ET-2 (C-8) Antibody sc-21627
Spezies, Gen, Gen ID, Chromosomaler Locus, mRNA (Isoform) Accession #, Protein Accession #, OMIM™ Nummer. Human, EDN2, 1907, 1p34.2, NM_001956 · P20800 ...
http://www.scbt.com/de/datasheet-21627-et-2-c-8-antibody.htm...

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