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EDN3


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Symbol:EDN3
Name(s):endothelin 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:ET3, MGC15067, MGC61498
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17009072 Observational study of genotype prevalence. (HuGE Navigator)
17554617 neither polymorphism nor mutation was observed in EDN3 in Chinese Hirschprung disease patients
14669347 Mutations are found in Hirschsprung's disease in a Chinese population.
16423827 KEL6 red blood cells have endothelin-3-converting enzyme activity

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDEndothelin 3endothelin receptor type A--Pubmed
HPRDendothelin 3 isoform 1 preproproteinEndothelin receptor, type A--Pubmed
HPRDendothelin 3 isoform 1 preproproteinEndothelin receptor, type A--Pubmed
HPRDendothelin 3 isoform 1 preproproteinendothelin receptor type B isoform 1 precursor--Pubmed
HPRDendothelin 3 isoform 1 preproproteinendothelin receptor type B isoform 1 precursor--Pubmed

Recent Publications on EDN3:

Pubmed Logo
Contribution of RET, NTRK3 and EDN3 to the expression of Hirschsprung disease in a multiplex family.
Hirschsprung disease (HSCR) is a developmental disorder due to a defect of...
27th June, 2009
Hospital Universitario Virgen del Rocio, Seville, Spain. J Med Genet. 2009 Jun 25.
DOI Direct Link
Gene expression profiling provides insights into the pathways involved in solid pseudopapillary neoplasm of the pancreas.
Solid-pseudopapillary neoplasms (SPNs) are rare human pancreatic neoplasms...
25th June, 2009
Institut Cochin, Universite Paris Descartes, CNRS (UMR 8104), Paris, J Pathol. 2009 Jun;218(2):201-9.
DOI Direct Link
Frequent loss of endothelin-3 (EDN3) expression due to epigenetic inactivation in human breast cancer.
INTRODUCTION: Endothelin (EDN) signalling plays a crucial role in cell...
17th June, 2009
Molecular Oncology Group, Institute of Pathology, University Hospital of Breast Cancer Res. 2009;11(3):R34. Epub 2009 Jun 15.
DOI Direct Link
The endothelin system: evolution of vertebrate-specific ligand-receptor interactions by three rounds of genome duplication.
Morphological innovations like the acquisition of the neural crest as well...
14th April, 2009
University of Wurzburg, Biozentrum, Physiological Chemistry I, Germany. Mol Biol Evol. 2009 Apr;26(4):783-99. Epub 2009 Jan 27.
DOI Direct Link
Analysis of RET, ZEB2, EDN3 and GDNF genomic rearrangements in 80 patients with Hirschsprung disease (using multiplex ligation-dependent probe amplification).
Hirschsprung disease (HSCR) is transmitted in a complex pattern of...
19th March, 2009
Departments of Pediatric Surgery and Surgical Research, Technische Ann Hum Genet. 2009 Mar;73(2):147-51. Epub 2009 Jan 14.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7592319 Uses of DNA-PK
6399298 Ku70--related methods
6673908 Tumor necrosis factor receptor 2
6808887 Uses of Ku70
7008768 Method for detecting radiation exposure

View more patents.

EDN3 results (if any) from reagent suppliers

Google CSE Logo
EDN3 monoclonal antibody (M01)
EDN3 (AAH08876, 1 a.a. ~ 239 a.a) full length recombinant protein with GST tag. ... Detection limit for recombinant GST tagged EDN3 is approximately ...
http://www.abgent.com/products/catalog_no/AT1852a_EDN3_monoc...

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ET-3 (5E8) Antibody sc-81944
... Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, EDN3, 1908, 20q13.32, NM_000114, NM_207032, NM_207033, NM_207034 · P14138 ...
http://www.scbt.com/datasheet-81944-et-3-5e8-antibody.html...

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Abgent - Neurosciences Antibodies
AT1852aNEW, EDN3 monoclonal antibody (M01), ELISA,S-ELISA,WB-Ce,WB-Re, H. AT1858aNEW, EFHD1 monoclonal antibody (M05), ELISA,WB-Ce,WB-Re, H ...
http://www.abgent.com/products/category/neurosciences...

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pan ET (3G10) Antibody sc-57396
Human, EDN3, 1908, 20q13.32, NM_000114, NM_207032, NM_207033, NM_207034 · P14138 · 277580. Ordering Information. Product Name, Catalog #, Unit, Price, Qty ...
http://www.scbt.com/datasheet-57396-pan-et-3g10-antibody.htm...

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pan ET (3G10) Antibody sc-57396
Human, EDN3, 1908, 20q13.32, NM_000114, NM_207032, NM_207033, NM_207034 · P14138 · 277580. 주문정보. 제품명, 카탈로그 번호, 단위, 가격, 수량, 관심상품 ...
http://www.scbt.com/ko/datasheet-57396-pan-et-3g10-antibody....

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Endothelin Antibody / Endothelin Antibodies
제품명, 카탈로그 번호, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. ET-1 (1C10) Antibody, sc-57116, mouse IgG1, N/A, ELISA, human ...
http://www.scbt.com/ko/table-endothelin.html...

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ET-3 (C-6) Antibody sc-21628
Human, EDN3, 1908, 20q13.32, NM_000114, NM_207032, NM_207033, NM_207034 · P14138 · 277580. Mouse, Edn3, 13616, 2 H4, P48299 ...
http://www.scbt.com/ko/datasheet-21628-et-3-c-6-antibody.htm...

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