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EEF1A1
| Symbol: | EEF1A1 | | Name(s): | eukaryotic translation elongation factor 1 alpha 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CCS-3, CCS3, EEF-1, EEF1A, EF-Tu, EF1A, FLJ25721, GRAF-1EF, HNGC:16303, LENG7, MGC102687, MGC131894, MGC16224, PTI1, eEF1A-1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18079119 |
both eEF1A and MYPT1 have roles in EGCG signaling for cancer prevention through 67LR |
| 17998013 |
Up-regulation of muscle EEF1A1 relates to proteolysis rate, suggesting an involvement of this gene in muscle catabolic response in hypercatabolic traumatized patients. |
| 15695360 |
analysis of the relationships between EF-Ts and EF-Tu from both yeasts and humans through functional complementation and coexpression experiments |
| 14623968 |
TCTP preferentially stabilized the GDP form of eEF1A, and, furthermore, impaired the GDP exchange reaction promoted by eEF1Bbeta. |
| 17373842 |
Endogenous HDM2- EF1alpha complex was detected in cancer cells overexpressing HDM2, suggesting a possible role of this interaction in HDM2-mediated oncogenesis. |
| 16354621 |
Our results indicate that neither EEF1A1 nor IMPG1 could be responsible for RP25 in the studied families due to absence of any pathogenic variants. |
| 17595531 |
identified the multifunctional eukaryotic translation elongation factor eEF1A1 as a novel interaction partner of PASKIN in the nuclei of testis germ cells and in the midpiece of sperm tails |
| 12594214 |
The fragile X mental retardation protein FMRP binds elongation factor 1A mRNA and negatively regulates its translation in vivo. |
| 12426393 |
Eukaryotic elongation factor 1A (eEF1A) and tRNA are RanGTP-dependent binding partners of exportin-5 (Exp5). Exp5 stimulates nuclear export of eEF1A and tRNA. |
| 16689924 |
The cytotoxicity of G-rich GT oligomers was shown to be tightly related to their binding affinity for eEF1A protein. | →View more information from publications. |
Recent Publications on EEF1A1: |  |
Region of elongation factor 1A1 involved in substrate recognition by Legionella pneumophila glucosyltransferase Lgt1: identification of Lgt1 as a retaining glucosyltransferase.
Lgt1 is one of the glucosyltransferases produced by the Gram-negative... | 29th September, 2009
| Gamaleya Research Institute, Moscow 123098, Russia.
| J Biol Chem. 2009 Jul 24;284(30):20167-74. Epub 2009 May 28.
DOI Direct Link |
Changes in global gene expression during in vitro decidualization of rat endometrial stromal cells.
During the preimplantation phase of pregnancy the endometrial stroma... | 26th September, 2009
| Instituto de Biologia y Medicina Experimental, Consejo Nacional de
| J Cell Physiol. 2009 Sep 24;222(1):127-137.
DOI Direct Link |
Networking of differentially expressed genes in human cancer cells resistant to methotrexate.
ABSTRACT : BACKGROUND : The need for an integrated view of data obtained... | 8th September, 2009
| Department of Biochemistry and Molecular Biology, School of Pharmacy,
| Genome Med. 2009 Sep 4;1(9):83.
DOI Direct Link |
The role of translation elongation factor eEF1A in intracellular alkalinization-induced tumor cell growth.
The formation of a pH gradient, which is characterized by intracellular... | 28th August, 2009
| Department of Pharmacology and Brain Korea 21 Project for Medical Science,
| Lab Invest. 2009 Aug;89(8):867-74. Epub 2009 Jun 8.
DOI Direct Link |
An axon regeneration signature in a Charcot-Marie-Tooth disease type 2 patient.
Charcot-Marie-Tooth disease (CMT) is one of the most common inherited... | 7th August, 2009
| Institute of Neurological Sciences, National Research Council, Mangone,
| J Neurogenet. 2009;23(3):324-8.
DOI Direct Link |
→View more research publications. |
EEF1A1 results (if any) from reagent suppliers | 
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eEF1A1 antibody (ab37969) | Abcam
Rabbit polyclonal to eEF1A1. eEF1A1 is an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery ...
http://www.abcam.com/eEF1A1-antibody-ab37969.html...
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EEF1A1 Antibody (N-term)
Western blot analysis of EEF1A1 antibody (N-term) (Cat. #AP6592a) in T47D cell line lysates (35ug/lane). EEF1A1 (arrow) was detected using the purified Pab.
...
http://www.abgent.com/products/catalog_no/AP6592a_EEF1A1_Ant...
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eEF1A1 antibodies: Chromatin and Nuclear Signaling > DNA / RNA ...
eEF1A1 antibodies. ... eEF1A1 antibody. WB, ICC/IF. Images · Customer Abreviews: 4 stars (out of 5) · Specific publication references. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=160952&pt=1&c=895&ei=&mu=r...
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EEF1A1 Antibody (C-term)
Western blot analysis of EEF1A1 Antibody (C-term) (Cat. #AP6592b) in MCF-7 cell line lysates ... EEF1A1 (arrow) was detected using the purified Pab. ...
http://www.abgent.com/products/catalog_no/AP6592b_EEF1A1_Ant...
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All Ribosome | Abcam
eEF1A1 antibody. WB, ICC/IF. Images · Customer Abreviews: 4 stars (out of 5) ... eEF1A1 protein (Tagged). FuncS. ab57876 · eEF1A2 binding protein antibody ...
http://www.abcam.com/index.html?c=895...
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Abgent - Translation and Regulation Antibodies ...
AT1813aNEW, DPH2 monoclonal antibody (M02), ELISA,IF,S-ELISA,WB-Ce,WB-Re, H. AP6592bNEW, EEF1A1 Antibody (C-term), WB, E, H ...
http://www.abgent.com/products/category/nuclear_signaling/tr...
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Panorama® Antibody Array - Signal Transduction
EEF1A1. eukaryotic translation elongation factor 1 alpha 1. 1915 · EFS. embryonal Fyn-associated substrate. 10278 · EGR2. early growth response 2 (Krox-
20 ...
http://www.sigmaaldrich.com/life-science/cell-biology/protei...
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