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EEF1A2
| Symbol: | EEF1A2 | | Name(s): | eukaryotic translation elongation factor 1 alpha 2 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | EEF1AL, EF-1-alpha-2, EF1A, HS1, STN | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17908984 |
EEF1A2 is highly homologous and functionally similar to the EEF1A1 oncogene, and was found to be restricted only to the normal tissues of the heart, brain, and skeletal muscle |
| 12053177 |
This is a putative oncogene in ovarian cancer. |
| 16156888 |
eEF1A2 may have a role in cytoskeletal remodelling or apoptosis in breast neoplasms |
| 17437010 |
The oncogenicity of eEF1A2 may be related either to its role in protein synthesis or to potential non-canonical functions. |
| 17088255 |
there is a physical and functional relationship between eEF1A2 and PI4KIIIbeta |
| 15893736 |
These results indicate that the use of cellular promoters such as those for EF-1alpha and ubiquitin C might direct prolonged gene expression in hematopoietic and mesenchymal progenitor cells. |
| 14588074 |
Review. EEF1A2 is an important ovarian oncogene. The protein elongation network can activate tumorigenesis and inhibit apoptosis. |
| 17130842 |
Regulates oncogenesis through Akt-dependent cytoskeletal remodeling. |
| 16369491 |
Overexpression of EEF1A2 and KCIP-1 is associated with lung adenocarcinoma |
Recent Publications on EEF1A2: |  |
The utrophin A 5'-UTR drives cap-independent translation exclusively in skeletal muscles of transgenic mice and interacts with eEF1A2.
The molecular mechanisms regulating expression of utrophin A are of... | 8th January, 2010
| Department of Cellular & Molecular Medicine and Center for Neuromuscular
| Hum Mol Genet. 2010 Jan 19.
DOI Direct Link |
eEF1A2 and neuronal degeneration.
Translation elongation factor eEF1A (eukaryotic elongation factor 1A)... | 6th January, 2010
| Medical Genetics Section, Molecular Medicine Centre, Institute of Genetics
| Biochem Soc Trans. 2009 Dec;37(Pt 6):1293-7.
DOI Direct Link |
Structural models of human eEF1A1 and eEF1A2 reveal two distinct surface clusters of sequence variation and potential differences in phosphorylation.
BACKGROUND: Despite sharing 92% sequence identity, paralogous human... | 11th November, 2009
| Medical Genetics Section, Molecular Medicine Centre, Institute of Genetics
| PLoS One. 2009 Jul 28;4(7):e6315.
DOI Direct Link |
Resveratrol suppresses growth of human ovarian cancer cells in culture and in a murine xenograft model: eukaryotic elongation factor 1A2 as a potential target.
The eukaryotic elongation factor 1A2 (eEF1A2) is known to retain oncogenic... | 8th October, 2009
| Department of Pharmacy, College of Pharmacy, and Cancer Research
| Cancer Res. 2009 Sep 15;69(18):7449-58. Epub 2009 Sep 8.
DOI Direct Link |
eEF1A2 as a putative oncogene.
The first evidence for the role of the protein elongation factor eEF1A2 in... | 24th September, 2009
| National Research Laboratory of Molecular Carcinogenesis and
| Ann N Y Acad Sci. 2009 Aug;1171:87-93.
DOI Direct Link |
→View more research publications. |
EEF1A2 results from Abnova |  | Sponsored Results: |
| EEF1A2 polyclonal antibody (A01)
Mouse polyclonal antibody raised against a partial recombinant EEF1A2. Symbol: EEF1A2 Alias: EEF1AL, EF1alpha2, EF1A, HS1, STN
http://www.abnova.com/products/products_detail.asp?catalog_id=H00001917-A01 |  |
| EEF1A2 Recombinant Protein (Q01)
EEF1A2( NP_001949, 364 a.a. - 462 a.a.) partial recombinant protein with GST tag. Symbol: EEF1A2 Alias: EEF1AL, EF1alpha2, EF1A, HS1, STN
http://www.abnova.com/products/products_detail.asp?catalog_id=H00001917-Q01 |  |
| EEF1A2 Recombinant Protein (P01)
EEF1A2( NP_001949.1, 1 a.a. - 463 a.a.) full-length recombinant protein with GST tag. Symbol: EEF1A2 Alias: EEF1AL, EF-1-alpha-2, EF1A, HS1, STN
http://www.abnova.com/products/products_detail.asp?catalog_id=H00001917-P01 |  |
| DKFZp434B1231 Pre-design Chimera RNAi
Homo sapiens eEF1A2 binding protein (DKFZp434B1231), mRNA. Symbol: DKFZp434B1231
http://www.abnova.com/products/products_detail.asp?catalog_id=H00091156-R01 |  |
| EEF1A2 Pre-design Chimera RNAi
Homo sapiens eukaryotic translation elongation factor 1 alpha 2 (EEF1A2), mRNA. Symbol: EEF1A2 Alias: EEF1AL, EF1alpha2, EF1A, HS1, STN
http://www.abnova.com/products/products_detail.asp?catalog_id=H00001917-R01 |  |
→Search for EEF1A2 products at Abnova. |
EEF1A2 results (if any) from reagent suppliers |
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EEF1A2 antibodies: Cancer > Oncoproteins/suppressors ...
EEF1A2 antibodies. ... Image Abreview Publication. ab82912 · EEF1A2 antibody. WB , ELISA. Images. Rabbit polyclonal. Reacts with: Hu, Ms, Rat ...
http://www.abcam.com/index.html?t=161715&pt=1&c=4332&ei=&mu=...
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EF-1α1 (H-300) Antibody sc-28578
Human, EEF1A2, 1917, 20q13.33, NM_001958 · Q05639 · 602959. Mouse, Eef1a1, 13627 , 9 E1, P10126, N/A. Mouse, Eef1a2, 13628, 2 H4, P62631 ...
http://www.scbt.com/datasheet-28578-ef-1alpha1-h-300-antibod...
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EEF1A2 proteins and peptides: Chromatin and Nuclear Signaling ...
EEF1A2 proteins and peptides. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab40317 · EEF1A2 protein (T7 Tag). SDS-PAGE, MS ...
http://www.abcam.com/index.html?t=161715&pt=2&c=894&ei=&mu=r...
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E-EI
SAB2100650, Anti-EEF1A2 antibody produced in rabbit New, polyclonal, affinity isolated antibody, human ... EEF1A2(1917) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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All tRNAs | Abcam
EEF1A2 antibody. WB, ELISA. Images. Rabbit polyclonal. Reacts with: Hu, Ms, Rat. ab40317 · EEF1A2 protein (T7 Tag). SDS-PAGE, MS ...
http://www.abcam.com/index.html?c=894...
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EF-1 α2 (D-15) Antibody sc-68481
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, EEF1A2, 1917, 20q13.33, Q05639 ...
http://www.scbt.com/datasheet-68481-ef-1-alpha2-d-15-antibod...
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Primary antibodies | Abcam
EEF1A2 antibody. WB, ELISA. Images. Rabbit polyclonal. Reacts with: Hu, Ms, Rat. ab57876 · eEF1A2 binding protein antibody ...
http://www.abcam.com/index.html?pageconfig=catalog_byproduct...
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